MX173596B - TIOL-ESTERS AND PROCEDURES FOR ITS PREPARATION - Google Patents

TIOL-ESTERS AND PROCEDURES FOR ITS PREPARATION

Info

Publication number
MX173596B
MX173596B MX1063288A MX1063288A MX173596B MX 173596 B MX173596 B MX 173596B MX 1063288 A MX1063288 A MX 1063288A MX 1063288 A MX1063288 A MX 1063288A MX 173596 B MX173596 B MX 173596B
Authority
MX
Mexico
Prior art keywords
alkyl
hydrogen
optionally substituted
nr6r7
alkoxy
Prior art date
Application number
MX1063288A
Other languages
Spanish (es)
Other versions
MX10632A (en
Inventor
Roger Edward Markwell
Stephen Allan Smith
Ian Hughes
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Priority to MX1063288A priority Critical patent/MX173596B/en
Publication of MX10632A publication Critical patent/MX10632A/en
Publication of MX173596B publication Critical patent/MX173596B/en

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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

La presente invención se refiere a un compuesto de la fórmula (I) o una sal, solvato o hidrato del mismo caracterizado porque R1 es -OH, alcoxi; aralquiloxi; -NR6R7, en donde daca uno de R6 y R7 es hidrógeno o alquilo; ó R6 y R7 juntos con el átomo e hidrógeno al que se encuntran ligados, forman un anillo con 5-, 6- ó 7- miembros con un oxígeno opcional, azufre o átomo de nitrógeno opcionalmente sustituido en el anillo; o un grupo donde R8 es hidrógeno; alquilo obsionalmente esustituido por -OH, alcoxi, -NR6R7, guanidina, -CO2H, CONH2, SH ó S-alquilo; ó -CH2-Ar, en donde Ar es arilo opcionalmente sustituido;y R9 es alcoxi; , ó -NR6R7; R2 es hidrógeno; -C-alquilo; ó - C - Z, en donde Z es arilo opcionalmente sustituido; R3 es alquilo con de 3 a 6 átomos de carbono; R4 es hidrógeno; alquilo; -CH2-R10, en donde R10 es fenilo opcidonalemnte sustituido; o heteroarilo; o un grupo en donde R11 en hidrógeno; alquilo ó -CH2-Ph en donde Ph es fenilo opcionalemnte sistituido; y R12 es hidrógeno ó alquilo; y R5 es hidrógeno o alquilo; o un grupo en donde R13 es hidrógeno o alquilo; y R14es hidroxi; alcosi; ó -NR6R7.The present invention relates to a compound of formula (I) or a salt, solvate or hydrate thereof characterized in that R1 is -OH, alkoxy; aralkyloxy; -NR6R7, where one of R6 and R7 is hydrogen or alkyl; or R6 and R7 together with the attached atom and hydrogen, form a ring with 5-, 6- or 7- members with an optional oxygen, sulfur or nitrogen atom optionally substituted on the ring; or a group where R8 is hydrogen; alkyl obsessively substituted by -OH, alkoxy, -NR6R7, guanidine, -CO2H, CONH2, SH or S-alkyl; or -CH2-Ar, where Ar is optionally substituted aryl, and R9 is alkoxy; , or -NR6R7; R2 is hydrogen; -C-alkyl; or -C-Z, where Z is optionally substituted aryl; R3 is alkyl with 3 to 6 carbon atoms; R4 is hydrogen; I rent; -CH2-R10, wherein R10 is optionally substituted phenyl; or heteroaryl; or a group where R11 in hydrogen; alkyl or -CH2-Ph where Ph is optionally substituted phenyl; and R12 is hydrogen or alkyl; and R5 is hydrogen or alkyl; or a group where R13 is hydrogen or alkyl; and R14 is hydroxy; alcosi; or -NR6R7.

MX1063288A 1988-03-03 1988-03-03 TIOL-ESTERS AND PROCEDURES FOR ITS PREPARATION MX173596B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MX1063288A MX173596B (en) 1988-03-03 1988-03-03 TIOL-ESTERS AND PROCEDURES FOR ITS PREPARATION

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX1063288A MX173596B (en) 1988-03-03 1988-03-03 TIOL-ESTERS AND PROCEDURES FOR ITS PREPARATION

Publications (2)

Publication Number Publication Date
MX10632A MX10632A (en) 1993-09-01
MX173596B true MX173596B (en) 1994-03-17

Family

ID=19741933

Family Applications (1)

Application Number Title Priority Date Filing Date
MX1063288A MX173596B (en) 1988-03-03 1988-03-03 TIOL-ESTERS AND PROCEDURES FOR ITS PREPARATION

Country Status (1)

Country Link
MX (1) MX173596B (en)

Also Published As

Publication number Publication date
MX10632A (en) 1993-09-01

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