MEP2608A - Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament - Google Patents

Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament

Info

Publication number
MEP2608A
MEP2608A MEP-26/08A MEP2608A MEP2608A ME P2608 A MEP2608 A ME P2608A ME P2608 A MEP2608 A ME P2608A ME P2608 A MEP2608 A ME P2608A
Authority
ME
Montenegro
Prior art keywords
phenylindan
trimethylpiperazine
chloro
succinate
trans
Prior art date
Application number
MEP-26/08A
Other languages
Bosnian (bs)
Inventor
De Diego Heidi Lopez
Ole Nielsen
Lone Munch Ringgard
Henrik Svane
Allan Carsten Dahl
Mark Howells
Benny Bang-Andersen
Lars Ole Lyngsoe
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Priority claimed from PCT/DK2004/000545 external-priority patent/WO2005016900A1/en
Publication of MEP2608A publication Critical patent/MEP2608A/en
Publication of ME00154B publication Critical patent/ME00154B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazin vodoniksukcinat ili vodonikmalonat, farmaceutski sastavi koji sadrže ove soli, i njihova medicinska upotreba, uklučujući liječenje šizofrenije i drugih psihotičkih poremećaja. Takođe su opisani postupci pripremanja 4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazina i njihove upotrebe u medicini.4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine hydrogen succinate or hydrogenmalonate, pharmaceutical compositions containing these salts, and their medical uses, including the treatment of schizophrenia and others psychotic disorders. Methods for the preparation of 4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine and their use in medicine are also described.

MEP-2008-26A 2003-08-18 2004-08-18 Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament ME00154B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49605803P 2003-08-18 2003-08-18
DKPA200301180 2003-08-18
US52024603P 2003-11-14 2003-11-14
PCT/DK2004/000545 WO2005016900A1 (en) 2003-08-18 2004-08-18 Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament

Publications (2)

Publication Number Publication Date
MEP2608A true MEP2608A (en) 2010-06-10
ME00154B ME00154B (en) 2010-10-10

Family

ID=36701685

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2008-26A ME00154B (en) 2003-08-18 2004-08-18 Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament

Country Status (4)

Country Link
CN (2) CN1835938A (en)
ME (1) ME00154B (en)
UA (2) UA108342C2 (en)
ZA (2) ZA200601173B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012523393A (en) * 2009-04-09 2012-10-04 エム・エス・ディー・オス・ベー・フェー Indane derivatives
CN103209949B (en) * 2010-11-09 2016-08-10 株式会社钟化 Halogenation indone class and use its optical activity indane ketone or the manufacture method of optical activity indane alcohols
CA2823103A1 (en) * 2011-01-07 2012-07-12 H. Lundbeck A/S Method for resolution of 4-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-3,3-dimethyl-piperazine
CN112359078A (en) * 2021-01-12 2021-02-12 凯莱英生命科学技术(天津)有限公司 Chiral resolution method of isobutyrate compound

Also Published As

Publication number Publication date
ZA200601421B (en) 2007-05-30
UA108342C2 (en) 2015-04-27
ZA200601173B (en) 2007-04-25
UA89617C2 (en) 2010-02-25
CN1839124A (en) 2006-09-27
ME00154B (en) 2010-10-10
CN1839124B (en) 2010-06-16
CN1835938A (en) 2006-09-20

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