ME00154B - Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament - Google Patents

Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament

Info

Publication number
ME00154B
ME00154B MEP-2008-26A MEP2608A ME00154B ME 00154 B ME00154 B ME 00154B ME P2608 A MEP2608 A ME P2608A ME 00154 B ME00154 B ME 00154B
Authority
ME
Montenegro
Prior art keywords
phenylindan
trimethylpiperazine
chloro
succinate
trans
Prior art date
Application number
MEP-2008-26A
Other languages
French (fr)
Unknown language (me)
Inventor
De Diego Heidi Lopez
Ole Nielsen
Lone Munch Ringgard
Henrik Svane
Allan Carsten Dahl
Mark Howells
Andersen Benny Bang
Lars Ole Lyngsø
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Priority claimed from PCT/DK2004/000545 external-priority patent/WO2005016900A1/en
Publication of MEP2608A publication Critical patent/MEP2608A/en
Publication of ME00154B publication Critical patent/ME00154B/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazin vodoniksukcinat ili vodonikmalonat, farmaceutski sastavi koji sadrže ove soli, i njihova medicinska upotreba, uključujući lečenje šizofrenije i drugih psihotičkih poremećaja . Takođe su opisani postupci pripremanja 4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazina i njihove upotrebe u medicini. 4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazin vodoniksukcinat ili vodonikmalonat, farmaceutski sastavi koji sadrže ove soli, i njihova medicinska upotreba, uključujući lečenje šizofrenije i drugih psihotičkih poremećaja . Takođe su opisani postupci pripremanja 4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazina i njihove upotrebe u medicini.4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine hydrogen succinate or hydrogenmalonate, pharmaceutical compositions containing these salts, and their medical uses, including treatment for schizophrenia and others psychotic disorders. Methods for the preparation of 4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine and their use in medicine are also described. 4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine hydrogen succinate or hydrogenmalonate, pharmaceutical compositions containing these salts, and their medical uses, including treatment for schizophrenia and others psychotic disorders. Methods for the preparation of 4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine and their use in medicine are also described.

MEP-2008-26A 2003-08-18 2004-08-18 Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament ME00154B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49605803P 2003-08-18 2003-08-18
DKPA200301180 2003-08-18
US52024603P 2003-11-14 2003-11-14
PCT/DK2004/000545 WO2005016900A1 (en) 2003-08-18 2004-08-18 Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament

Publications (2)

Publication Number Publication Date
MEP2608A MEP2608A (en) 2010-06-10
ME00154B true ME00154B (en) 2010-10-10

Family

ID=36701685

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2008-26A ME00154B (en) 2003-08-18 2004-08-18 Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament

Country Status (4)

Country Link
CN (2) CN1835938A (en)
ME (1) ME00154B (en)
UA (2) UA108342C2 (en)
ZA (2) ZA200601173B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010115952A1 (en) * 2009-04-09 2010-10-14 N.V. Organon Indane derivatives
EP2639216B1 (en) * 2010-11-09 2018-07-11 Kaneka Corporation Halogenated indenones and method for producing optically active indanones or optically active indanols by using same
CN103429577A (en) * 2011-01-07 2013-12-04 H.隆德贝克有限公司 Method for resolution of 4-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1R,3S)-6-chloro-3-phenyl-indan, 1-yl)-3,3-dimethyl-piperazine
CN112359078A (en) * 2021-01-12 2021-02-12 凯莱英生命科学技术(天津)有限公司 Chiral resolution method of isobutyrate compound

Also Published As

Publication number Publication date
UA89617C2 (en) 2010-02-25
ZA200601173B (en) 2007-04-25
CN1839124B (en) 2010-06-16
CN1835938A (en) 2006-09-20
UA108342C2 (en) 2015-04-27
CN1839124A (en) 2006-09-27
ZA200601421B (en) 2007-05-30
MEP2608A (en) 2010-06-10

Similar Documents

Publication Publication Date Title
MXPA06001838A (en) Succinate and malonate salt of trans-4-(ir, 3s)-6 -chloro- 3-phenylindan- 1-yl)-1, 2, 2- trimethylpiperazine and the use as a medicament.
NO20065904L (en) Therapeutic compounds
SE0401971D0 (en) Piperidne derivatives
ATE269846T1 (en) N-SUBSTITUTED AMINOTETRALINES AS NEUROPEPTIDE Y Y5 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF OBESITY AND OTHER DISEASES
MY145590A (en) Phenylacetamides and their use as glucokinase modulators
CY1118179T1 (en) PHARMACEUTICAL COMPOSITION
HK1140377A1 (en) Pharmaceutical use of substituted amides
CY1112376T1 (en) 2,3,4,9-tetrahydro-1H-carvasol derivative as CRTH2 receptor antagonists
BRPI0418251B8 (en) phosphonates, monophosphonamidates, bisphosphonamidates, and pharmaceutical composition comprising them
CY1108932T1 (en) Compounds 4- (heterocyclyl) -benzenesulfoximine for the therapeutic treatment of inflammatory diseases
ATE508114T1 (en) ISOINDOLYL COMPOUNDS SUBSTITUTED WITH N-ALKYLHYDROXAMIC ACIDS AND THEIR PHARMACEUTICAL USE
WO2005037798A3 (en) Amide or thiomide derivatives and their use in the treatment of pain
SG155181A1 (en) Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
SE0401970D0 (en) Novel compounds
DE602005010744D1 (en) PIPERAZINYLPYRIDINE DERIVATIVES AS AGENTS AGAINST ADIPOSITAS
SE0402762D0 (en) Indazole sulphonamide derivatives
ATE541567T1 (en) PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF METABOLIC BONE DISEASES USING ALPHA-ARYL METHOXYACRYLATE DERIVATIVES
SE0102147D0 (en) New methods
SE0300105D0 (en) Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
ME00154B (en) Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament
CY1111361T1 (en) NEW DESIGNS RAR RECEPTORS ASSOCIATES, USE IN HUMAN MEDICAL AND IN COSMETOLOGY
DE60135390D1 (en) USE OF NEFIRACETAM FOR THE TREATMENT OF POSTIC MIXER NEURODEGENERATION
DE60322110D1 (en) SUBSTITUTED 4- (4-PIPERIDIN-YL-PIPERAZIN-1-YL) -AZNTAGONISTS
MY149089A (en) Succinate and malonate salt of trans-4-((1r,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament
SE0301445D0 (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof