ME00154B - Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament - Google Patents
Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicamentInfo
- Publication number
- ME00154B ME00154B MEP-2008-26A MEP2608A ME00154B ME 00154 B ME00154 B ME 00154B ME P2608 A MEP2608 A ME P2608A ME 00154 B ME00154 B ME 00154B
- Authority
- ME
- Montenegro
- Prior art keywords
- phenylindan
- trimethylpiperazine
- chloro
- succinate
- trans
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazin vodoniksukcinat ili vodonikmalonat, farmaceutski sastavi koji sadrže ove soli, i njihova medicinska upotreba, uključujući lečenje šizofrenije i drugih psihotičkih poremećaja . Takođe su opisani postupci pripremanja 4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazina i njihove upotrebe u medicini. 4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazin vodoniksukcinat ili vodonikmalonat, farmaceutski sastavi koji sadrže ove soli, i njihova medicinska upotreba, uključujući lečenje šizofrenije i drugih psihotičkih poremećaja . Takođe su opisani postupci pripremanja 4-((1R,3S)-6-hloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazina i njihove upotrebe u medicini.4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine hydrogen succinate or hydrogenmalonate, pharmaceutical compositions containing these salts, and their medical uses, including treatment for schizophrenia and others psychotic disorders. Methods for the preparation of 4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine and their use in medicine are also described. 4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine hydrogen succinate or hydrogenmalonate, pharmaceutical compositions containing these salts, and their medical uses, including treatment for schizophrenia and others psychotic disorders. Methods for the preparation of 4 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -1,2,2-trimethylpiperazine and their use in medicine are also described.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49605803P | 2003-08-18 | 2003-08-18 | |
DKPA200301180 | 2003-08-18 | ||
US52024603P | 2003-11-14 | 2003-11-14 | |
PCT/DK2004/000545 WO2005016900A1 (en) | 2003-08-18 | 2004-08-18 | Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
MEP2608A MEP2608A (en) | 2010-06-10 |
ME00154B true ME00154B (en) | 2010-10-10 |
Family
ID=36701685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2008-26A ME00154B (en) | 2003-08-18 | 2004-08-18 | Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament |
Country Status (4)
Country | Link |
---|---|
CN (2) | CN1835938A (en) |
ME (1) | ME00154B (en) |
UA (2) | UA89617C2 (en) |
ZA (2) | ZA200601421B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102365265A (en) * | 2009-04-09 | 2012-02-29 | 欧加农股份有限公司 | Indane derivatives |
JP5941410B2 (en) * | 2010-11-09 | 2016-06-29 | 株式会社カネカ | Halogenated indenones and methods for producing optically active indanones or optically active indanols using the same |
EP2661427A1 (en) * | 2011-01-07 | 2013-11-13 | H. Lundbeck A/S | Method for resolution of 4-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1r,3s)-6-chloro-3-phenyl-indan, 1-yl)-3,3-dimethyl-piperazine |
CN112359078A (en) * | 2021-01-12 | 2021-02-12 | 凯莱英生命科学技术(天津)有限公司 | Chiral resolution method of isobutyrate compound |
-
2004
- 2004-08-18 ME MEP-2008-26A patent/ME00154B/en unknown
- 2004-08-18 UA UAA200602709A patent/UA89617C2/en unknown
- 2004-08-18 ZA ZA200601421A patent/ZA200601421B/en unknown
- 2004-08-18 ZA ZA200601173A patent/ZA200601173B/en unknown
- 2004-08-18 UA UAA200909651A patent/UA108342C2/en unknown
- 2004-08-18 CN CNA2004800236381A patent/CN1835938A/en active Pending
- 2004-08-18 CN CN2004800237257A patent/CN1839124B/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ZA200601173B (en) | 2007-04-25 |
ZA200601421B (en) | 2007-05-30 |
MEP2608A (en) | 2010-06-10 |
UA89617C2 (en) | 2010-02-25 |
CN1839124A (en) | 2006-09-27 |
UA108342C2 (en) | 2015-04-27 |
CN1839124B (en) | 2010-06-16 |
CN1835938A (en) | 2006-09-20 |
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