MD88C2 - The process for obtaining the the N-(2-(4-fluorphenyl)-1 methyl)-ethyl-N-propynylamine in kind of racemate or his L-isomer, and his salts. - Google Patents

The process for obtaining the the N-(2-(4-fluorphenyl)-1 methyl)-ethyl-N-propynylamine in kind of racemate or his L-isomer, and his salts.

Info

Publication number
MD88C2
MD88C2 MD94-0137A MD940137A MD88C2 MD 88 C2 MD88 C2 MD 88C2 MD 940137 A MD940137 A MD 940137A MD 88 C2 MD88 C2 MD 88C2
Authority
MD
Moldova
Prior art keywords
obtaining
propynylamine
fluorphenyl
ethyl
methyl
Prior art date
Application number
MD94-0137A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD88B1 (en
Inventor
Zoltan Ecsery
Jozsef Knoll
Eva Somfai
Torok Zoltan
Eva Szinnyei
Karoly Moszolits
Original Assignee
Chinoin Gyogyszer -Es Vegyeszeti Termekek Gyara Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU842124A external-priority patent/HU207282B/en
Application filed by Chinoin Gyogyszer -Es Vegyeszeti Termekek Gyara Rt. filed Critical Chinoin Gyogyszer -Es Vegyeszeti Termekek Gyara Rt.
Publication of MD88B1 publication Critical patent/MD88B1/en
Publication of MD88C2 publication Critical patent/MD88C2/en

Links

Abstract

The invention relates to the amines, in particular to obtaining theN-[2-(4-fluorphenyl)-1 methyl]-ethyl-N-propynylamine which has the antidepresive action, that could be used in medicine. The purpose of the invention consists in the creation of the new more active compound of this group. The synthesis was happening in the chemical compounds condensation: 4-F-C6H4-CH2-CH(CH3)-NH-CH3 and B-R, in which B-is haloid R=CH2-C=CH; CH2-CBr=CH2.If the R=CH2 CBr=CH2, the obtaining product is exposed to dehydrogaloidiration and the special product is envolved in racement form, L-isomer free or in his salt necessary form. The new compounds was lesser toxic, more active and selective than the inhibiting MAO-B type.
MD94-0137A 1984-05-31 1994-04-21 The process for obtaining the the N-(2-(4-fluorphenyl)-1 methyl)-ethyl-N-propynylamine in kind of racemate or his L-isomer, and his salts. MD88C2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HU842124A HU207282B (en) 1984-05-31 1984-05-31 Process for producing phenyl-alkyl-amine derivatives and pharmaceutical compositions containing them
PCT/HU1985/000035 WO1985005617A1 (en) 1984-05-31 1985-05-31 Phenylisopropylamine derivative and its preparation
SU864015073A SU1487810A3 (en) 1984-05-31 1986-01-30 Method of producing n-/2-(4-fluorophenyl))-1-methyl/-ethyl-n-methyl-n-propylniamine
SU864027653A SU1609443A3 (en) 1984-05-31 1986-06-16 Method of producing n-/2-(4-fluorophenyl)-1methyl/-ethyl-n-methyl-n-propylamine as racemate or l-isomer, or their salts

Publications (2)

Publication Number Publication Date
MD88B1 MD88B1 (en) 1994-11-30
MD88C2 true MD88C2 (en) 1995-03-31

Family

ID=27269987

Family Applications (1)

Application Number Title Priority Date Filing Date
MD94-0137A MD88C2 (en) 1984-05-31 1994-04-21 The process for obtaining the the N-(2-(4-fluorphenyl)-1 methyl)-ethyl-N-propynylamine in kind of racemate or his L-isomer, and his salts.

Country Status (1)

Country Link
MD (1) MD88C2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH52468A (en) * 1910-07-19 1911-11-16 Elektrometall Ab Equipment on electric ovens for blowing gas into the same to cool the electrodes and the masonry
US3485874A (en) * 1966-05-04 1969-12-23 Chinoin Gyogyszer Es Vegyeszet Ortho and para bromophenyl isopropyl methylamines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH52468A (en) * 1910-07-19 1911-11-16 Elektrometall Ab Equipment on electric ovens for blowing gas into the same to cool the electrodes and the masonry
US3485874A (en) * 1966-05-04 1969-12-23 Chinoin Gyogyszer Es Vegyeszet Ortho and para bromophenyl isopropyl methylamines

Also Published As

Publication number Publication date
MD88B1 (en) 1994-11-30

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20050530