MD88C2 - The process for obtaining the the N-(2-(4-fluorphenyl)-1 methyl)-ethyl-N-propynylamine in kind of racemate or his L-isomer, and his salts. - Google Patents
The process for obtaining the the N-(2-(4-fluorphenyl)-1 methyl)-ethyl-N-propynylamine in kind of racemate or his L-isomer, and his salts.Info
- Publication number
- MD88C2 MD88C2 MD94-0137A MD940137A MD88C2 MD 88 C2 MD88 C2 MD 88C2 MD 940137 A MD940137 A MD 940137A MD 88 C2 MD88 C2 MD 88C2
- Authority
- MD
- Moldova
- Prior art keywords
- obtaining
- propynylamine
- fluorphenyl
- ethyl
- methyl
- Prior art date
Links
Abstract
The invention relates to the amines, in particular to obtaining theN-[2-(4-fluorphenyl)-1 methyl]-ethyl-N-propynylamine which has the antidepresive action, that could be used in medicine. The purpose of the invention consists in the creation of the new more active compound of this group. The synthesis was happening in the chemical compounds condensation: 4-F-C6H4-CH2-CH(CH3)-NH-CH3 and B-R, in which B-is haloid R=CH2-C=CH; CH2-CBr=CH2.If the R=CH2 CBr=CH2, the obtaining product is exposed to dehydrogaloidiration and the special product is envolved in racement form, L-isomer free or in his salt necessary form. The new compounds was lesser toxic, more active and selective than the inhibiting MAO-B type.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU842124A HU207282B (en) | 1984-05-31 | 1984-05-31 | Process for producing phenyl-alkyl-amine derivatives and pharmaceutical compositions containing them |
PCT/HU1985/000035 WO1985005617A1 (en) | 1984-05-31 | 1985-05-31 | Phenylisopropylamine derivative and its preparation |
SU864015073A SU1487810A3 (en) | 1984-05-31 | 1986-01-30 | Method of producing n-/2-(4-fluorophenyl))-1-methyl/-ethyl-n-methyl-n-propylniamine |
SU864027653A SU1609443A3 (en) | 1984-05-31 | 1986-06-16 | Method of producing n-/2-(4-fluorophenyl)-1methyl/-ethyl-n-methyl-n-propylamine as racemate or l-isomer, or their salts |
Publications (2)
Publication Number | Publication Date |
---|---|
MD88B1 MD88B1 (en) | 1994-11-30 |
MD88C2 true MD88C2 (en) | 1995-03-31 |
Family
ID=27269987
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MD94-0137A MD88C2 (en) | 1984-05-31 | 1994-04-21 | The process for obtaining the the N-(2-(4-fluorphenyl)-1 methyl)-ethyl-N-propynylamine in kind of racemate or his L-isomer, and his salts. |
Country Status (1)
Country | Link |
---|---|
MD (1) | MD88C2 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH52468A (en) * | 1910-07-19 | 1911-11-16 | Elektrometall Ab | Equipment on electric ovens for blowing gas into the same to cool the electrodes and the masonry |
US3485874A (en) * | 1966-05-04 | 1969-12-23 | Chinoin Gyogyszer Es Vegyeszet | Ortho and para bromophenyl isopropyl methylamines |
-
1994
- 1994-04-21 MD MD94-0137A patent/MD88C2/en active IP Right Grant
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH52468A (en) * | 1910-07-19 | 1911-11-16 | Elektrometall Ab | Equipment on electric ovens for blowing gas into the same to cool the electrodes and the masonry |
US3485874A (en) * | 1966-05-04 | 1969-12-23 | Chinoin Gyogyszer Es Vegyeszet | Ortho and para bromophenyl isopropyl methylamines |
Also Published As
Publication number | Publication date |
---|---|
MD88B1 (en) | 1994-11-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG4A | Patent for invention issued | ||
IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20050530 |