MD840Z - Метод прогнозирования риска смертности в постинфарктном периоде острого инфаркта миокарда - Google Patents
Метод прогнозирования риска смертности в постинфарктном периоде острого инфаркта миокарда Download PDFInfo
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- MD840Z MD840Z MDS20140067A MDS20140067A MD840Z MD 840 Z MD840 Z MD 840Z MD S20140067 A MDS20140067 A MD S20140067A MD S20140067 A MDS20140067 A MD S20140067A MD 840 Z MD840 Z MD 840Z
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- risk
- death
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- 238000000034 method Methods 0.000 title claims abstract description 10
- 206010000891 acute myocardial infarction Diseases 0.000 title abstract description 14
- 206010061216 Infarction Diseases 0.000 title abstract description 8
- 239000008280 blood Substances 0.000 claims abstract description 21
- 210000004369 blood Anatomy 0.000 claims abstract description 21
- 102100032752 C-reactive protein Human genes 0.000 claims abstract description 17
- WSMYVTOQOOLQHP-UHFFFAOYSA-N Malondialdehyde Chemical compound O=CCC=O WSMYVTOQOOLQHP-UHFFFAOYSA-N 0.000 claims abstract description 16
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 13
- 239000008103 glucose Substances 0.000 claims abstract description 13
- 108010074051 C-Reactive Protein Proteins 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 4
- 208000010125 myocardial infarction Diseases 0.000 claims description 5
- 230000001154 acute effect Effects 0.000 claims 1
- 229940118019 malondialdehyde Drugs 0.000 abstract description 9
- 239000003814 drug Substances 0.000 abstract description 2
- 238000004393 prognosis Methods 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 3
- 206010002383 Angina Pectoris Diseases 0.000 description 2
- 206010018429 Glucose tolerance impaired Diseases 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 238000007410 oral glucose tolerance test Methods 0.000 description 2
- 238000013517 stratification Methods 0.000 description 2
- 208000002705 Glucose Intolerance Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000009785 Inferior Wall Myocardial Infarction Diseases 0.000 description 1
- 238000002399 angioplasty Methods 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 230000002641 glycemic effect Effects 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 201000009526 inferior myocardial infarction Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000000491 multivariate analysis Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000002537 thrombolytic effect Effects 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
Изобретение относится к медицине, в частности к кардиологии, и может быть использовано для прогнозирования риска смертности в постинфарктном периоде острого инфаркта миокарда.Согласно изобретению, заявленный метод состоит в том, что у пациента, на 10-й день госпитализации, забирают пробу крови, в которой определяют концентрацию С реактивного белка и малонового диальдегида, затем, per os, вводят раствор содержащий 75 г глюкозы и 250 мл воды, после чего, через 120 мин, забирают другую пробу крови, в которой определяют гликемию и в случае когда гликемия выше 8,7 ммол/л, концентрация С реактивного белка выше 9,8 мг/л и малонового диальдегида выше 3,51 µМ/л прогнозируют повышенный риск смертности, в случае когда гликемия соответствует величинам 7,7…8,7 ммол/л, концентрация С реактивного белка 3,0…9,8 мг/л и малонового диальдегида 1,9…3,51 µМ/л - средний риск смертности, а когда гликемия ниже 7,7 ммол/л, концентрация С реактивного белка ниже 3,0 мг/л и малонового диальдегида ниже 1,9 µМ/л - минимальный риск смертности.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20140067A MD840Z (ru) | 2014-05-15 | 2014-05-15 | Метод прогнозирования риска смертности в постинфарктном периоде острого инфаркта миокарда |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20140067A MD840Z (ru) | 2014-05-15 | 2014-05-15 | Метод прогнозирования риска смертности в постинфарктном периоде острого инфаркта миокарда |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD840Y MD840Y (ru) | 2014-11-30 |
| MD840Z true MD840Z (ru) | 2015-06-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| MDS20140067A MD840Z (ru) | 2014-05-15 | 2014-05-15 | Метод прогнозирования риска смертности в постинфарктном периоде острого инфаркта миокарда |
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| MD (1) | MD840Z (ru) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD530Y (ru) * | 2011-11-07 | 2012-07-31 | Ina Palii | Метод прогнозирования эволюции врожденной сердечной недостаточности у детей, осложненной легочной гипертензией |
| MD547Y (ru) * | 2011-11-07 | 2012-10-31 | Инна ПАЛИЙ | Метод прогнозирования эволюции врожденной сердечной недостаточности у детей, осложненной легочной гипертензией |
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2014
- 2014-05-15 MD MDS20140067A patent/MD840Z/ru not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD530Y (ru) * | 2011-11-07 | 2012-07-31 | Ina Palii | Метод прогнозирования эволюции врожденной сердечной недостаточности у детей, осложненной легочной гипертензией |
| MD547Y (ru) * | 2011-11-07 | 2012-10-31 | Инна ПАЛИЙ | Метод прогнозирования эволюции врожденной сердечной недостаточности у детей, осложненной легочной гипертензией |
Non-Patent Citations (1)
| Title |
|---|
| Tamita K., Katayama M., Takagi T., et al. Newly diagnosed glucose intolerance and prognosis after acute myocardial infarction: comparison of post-challenge versus fasting glucose concentrations. 2012, p. 98, 848-854 * |
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| Publication number | Publication date |
|---|---|
| MD840Y (ru) | 2014-11-30 |
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| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) | ||
| MM4Y | Short-term patent definitely lapsed due to non-payment of fees |