MD655Z - Метод гемостаза ран после некрэктомии у пациентов с тяжелыми коагулопатиями на фоне декомпенсированного цирроза печени - Google Patents
Метод гемостаза ран после некрэктомии у пациентов с тяжелыми коагулопатиями на фоне декомпенсированного цирроза печениInfo
- Publication number
- MD655Z MD655Z MDS20120156A MDS20120156A MD655Z MD 655 Z MD655 Z MD 655Z MD S20120156 A MDS20120156 A MD S20120156A MD S20120156 A MDS20120156 A MD S20120156A MD 655 Z MD655 Z MD 655Z
- Authority
- MD
- Moldova
- Prior art keywords
- necrectomy
- patients
- thrombin
- cryoprecipitate
- dose
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 17
- 230000023597 hemostasis Effects 0.000 title claims abstract description 12
- 206010053567 Coagulopathies Diseases 0.000 title claims abstract description 9
- 208000019425 cirrhosis of liver Diseases 0.000 title claims abstract description 9
- 108090000190 Thrombin Proteins 0.000 claims abstract description 16
- 229960004072 thrombin Drugs 0.000 claims abstract description 16
- 108010049003 Fibrinogen Proteins 0.000 claims abstract description 8
- 102000008946 Fibrinogen Human genes 0.000 claims abstract description 8
- 229940012952 fibrinogen Drugs 0.000 claims abstract description 8
- 108010054218 Factor VIII Proteins 0.000 claims abstract description 6
- 102000001690 Factor VIII Human genes 0.000 claims abstract description 6
- 229940105778 coagulation factor viii Drugs 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims abstract description 6
- 206010052428 Wound Diseases 0.000 claims description 20
- 208000027418 Wounds and injury Diseases 0.000 claims description 20
- 208000015294 blood coagulation disease Diseases 0.000 claims description 4
- 239000003814 drug Substances 0.000 abstract description 2
- 230000001338 necrotic effect Effects 0.000 description 8
- 210000001519 tissue Anatomy 0.000 description 7
- 208000032843 Hemorrhage Diseases 0.000 description 5
- 230000000740 bleeding effect Effects 0.000 description 4
- 230000001788 irregular Effects 0.000 description 4
- 238000011477 surgical intervention Methods 0.000 description 4
- 238000001356 surgical procedure Methods 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 108010094028 Prothrombin Proteins 0.000 description 2
- 102100027378 Prothrombin Human genes 0.000 description 2
- 206010041660 Splenomegaly Diseases 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 230000009852 coagulant defect Effects 0.000 description 2
- 239000000306 component Substances 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- 201000004108 hypersplenism Diseases 0.000 description 2
- 210000003141 lower extremity Anatomy 0.000 description 2
- 208000007232 portal hypertension Diseases 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000011321 prophylaxis Methods 0.000 description 2
- 229940039716 prothrombin Drugs 0.000 description 2
- 230000001172 regenerating effect Effects 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 206010051814 Eschar Diseases 0.000 description 1
- 206010060840 Ischaemic cerebral infarction Diseases 0.000 description 1
- 206010033892 Paraplegia Diseases 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 208000014306 Trophic disease Diseases 0.000 description 1
- 206010048038 Wound infection Diseases 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000003831 deregulation Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 231100000333 eschar Toxicity 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 210000000954 sacrococcygeal region Anatomy 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 201000005060 thrombophlebitis Diseases 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Изобретение относится к медицине, в частности к методам гемостаза ран после некрэктомии у пациентов с тяжелыми коагулопатиями на фоне декомпенсированного цирроза печени.Согласно изобретению, заявленный метод состоит в том, что на рану накладывают марлевую повязку площадью 100 см2, в два слоя, пропитанную смесью, содержащей криопреципитат и тромбин, взятые в соотношение 2:4 дозы соответственно, где одна доза криопреципитата содержит свертывающий фактор VIII в количестве 100 МЕ и 250 мг фибриногена, а одна доза тромбина содержит 125 МЕ.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20120156A MD655Z (ru) | 2012-11-08 | 2012-11-08 | Метод гемостаза ран после некрэктомии у пациентов с тяжелыми коагулопатиями на фоне декомпенсированного цирроза печени |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20120156A MD655Z (ru) | 2012-11-08 | 2012-11-08 | Метод гемостаза ран после некрэктомии у пациентов с тяжелыми коагулопатиями на фоне декомпенсированного цирроза печени |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD655Y MD655Y (en) | 2013-07-31 |
| MD655Z true MD655Z (ru) | 2014-03-31 |
Family
ID=48875338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20120156A MD655Z (ru) | 2012-11-08 | 2012-11-08 | Метод гемостаза ран после некрэктомии у пациентов с тяжелыми коагулопатиями на фоне декомпенсированного цирроза печени |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD655Z (ru) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD2328G2 (ru) * | 2003-07-14 | 2004-07-31 | Константин ЦЫБЫРНЭ | Фибринный клей и его использование для эндоскопического гемостаза варикозных кровотечений при циррозе печени |
| MD372Z (ru) * | 2010-11-30 | 2011-12-31 | Георге АНГЕЛИЧ | Эндоскопический метод гемостаза кровоточащей язвы при декомпенсированном циррозе печени |
-
2012
- 2012-11-08 MD MDS20120156A patent/MD655Z/ru not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD2328G2 (ru) * | 2003-07-14 | 2004-07-31 | Константин ЦЫБЫРНЭ | Фибринный клей и его использование для эндоскопического гемостаза варикозных кровотечений при циррозе печени |
| MD372Z (ru) * | 2010-11-30 | 2011-12-31 | Георге АНГЕЛИЧ | Эндоскопический метод гемостаза кровоточащей язвы при декомпенсированном циррозе печени |
Non-Patent Citations (2)
| Title |
|---|
| Апарцин К. Хирургия тяжелых гнойных процесcов. Под ред. Григорьева Б. Г. Новосибирск, 2003, p. 346 * |
| Кузин М., Костиченюк Б. Раны и раневая инфекция. Москва, 1990, p. 591 * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD655Y (en) | 2013-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Moore et al. | Fibrin sealant reduces the duration and amount of fluid1 drainage after axillary dissection: A randomized prospective clinical trial | |
| Dowsett et al. | Wound bed preparation: TIME in practice | |
| Panuncialman et al. | The science of wound bed preparation | |
| Caputo et al. | A prospective randomised controlled clinical trial comparing hydrosurgery debridement with conventional surgical debridement in lower extremity ulcers | |
| Pabinger et al. | Tranexamic acid for treatment and prophylaxis of bleeding and hyperfibrinolysis | |
| Cipolla et al. | Does the use of fibrin glue prevent seroma formation after axillary lymphadenectomy for breast cancer? A prospective randomized trial in 159 patients | |
| Sterling et al. | Hemostasis in burn surgery—a review | |
| Menke et al. | Biologic therapeutics and molecular profiling to optimize wound healing | |
| KR20010071577A (ko) | 혈소판이 풍부한 개선된 상처 치유제 | |
| Krejner et al. | Modulation of matrix metalloproteinases MMP-2 and MMP-9 activity by hydrofiber-foam hybrid dressing–relevant support in the treatment of chronic wounds | |
| Huber et al. | A case series of platelet rich plasma in chronic venous ulcers | |
| US20020049471A1 (en) | Method and hemostatic patch for effecting local hemostasis | |
| Tanaka et al. | Treatment of massive bleeding with prothrombin complex concentrate: argument for | |
| Rani et al. | A comparative evaluation of topical application versus perilesional injection of platelet-rich plasma in diabetic foot ulcer | |
| JP3993981B2 (ja) | 改良された濃縮血小板創傷治癒剤に対する特許の適用 | |
| AU2019394837B2 (en) | Wound treatment gel obtainable by combining platelet rich plasma with autologously derived thrombin | |
| WO2019040185A1 (en) | SARRASIN HONEY AND HEALING WELDING FOR IODIZED POVIDONE WOUND | |
| WO2019078931A1 (en) | SARRASIN HONEY AND HEALING WELDING FOR BACITRACIN-BASED WAFER | |
| MD655Z (ru) | Метод гемостаза ран после некрэктомии у пациентов с тяжелыми коагулопатиями на фоне декомпенсированного цирроза печени | |
| Jurasz et al. | Matrix metalloproteinase-2 contributes to increased platelet reactivity in patients with metastatic prostate cancer: a preliminary study | |
| Madhu et al. | Effect of topical hemocoagulase therapy in wound healing | |
| Lozner et al. | The so-called “coagulation defect” in menstrual blood | |
| Wound Bed Advisory Board et al. | Principles of wound bed preparation and their application to the treatment of chronic wounds | |
| Teitelman et al. | Enzymatic debridement of necrotic surfaces | |
| CN119661696B (zh) | 一种多肽pm7及其在防治血栓中的应用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG9Y | Short term patent issued | ||
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) | ||
| MM4Y | Short-term patent definitely lapsed due to non-payment of fees |