MD462Z - Метод прогнозирования эволюции ювенильного идеопатического артрита - Google Patents
Метод прогнозирования эволюции ювенильного идеопатического артрита Download PDFInfo
- Publication number
- MD462Z MD462Z MDS20110123A MDS20110123A MD462Z MD 462 Z MD462 Z MD 462Z MD S20110123 A MDS20110123 A MD S20110123A MD S20110123 A MDS20110123 A MD S20110123A MD 462 Z MD462 Z MD 462Z
- Authority
- MD
- Moldova
- Prior art keywords
- disease
- evolution
- idiopathic arthritis
- juvenile idiopathic
- nad
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 15
- 208000003456 Juvenile Arthritis Diseases 0.000 title claims description 21
- 206010059176 Juvenile idiopathic arthritis Diseases 0.000 title claims description 21
- 201000002215 juvenile rheumatoid arthritis Diseases 0.000 title claims description 21
- 201000010099 disease Diseases 0.000 claims abstract description 32
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 32
- 208000006820 Arthralgia Diseases 0.000 claims abstract description 9
- BAWFJGJZGIEFAR-NNYOXOHSSA-O NAD(+) Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-O 0.000 claims description 2
- 206010003246 arthritis Diseases 0.000 abstract description 3
- 239000003814 drug Substances 0.000 abstract description 3
- 230000000366 juvenile effect Effects 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 238000004393 prognosis Methods 0.000 description 4
- 230000009885 systemic effect Effects 0.000 description 4
- 238000001514 detection method Methods 0.000 description 3
- 230000002349 favourable effect Effects 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 102000011767 Acute-Phase Proteins Human genes 0.000 description 1
- 108010062271 Acute-Phase Proteins Proteins 0.000 description 1
- 208000008822 Ankylosis Diseases 0.000 description 1
- 206010023198 Joint ankylosis Diseases 0.000 description 1
- 206010023204 Joint dislocation Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 230000009760 functional impairment Effects 0.000 description 1
- 208000037824 growth disorder Diseases 0.000 description 1
- LELAOEBVZLPXAZ-UHFFFAOYSA-N iberin Chemical compound CS(=O)CCCN=C=S LELAOEBVZLPXAZ-UHFFFAOYSA-N 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000008774 maternal effect Effects 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 238000002601 radiography Methods 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 210000005065 subchondral bone plate Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретение относится к медицине, в частности к детской ревматологии.Метод, согласно изобретению, включает клиническое и параклиническое обследования, которые выявляют следующие параметры: возраст пациента (VD) в начале заболевания, длительность заболевания (DM), число болезненных суставов (NAD) в начале заболевания, рентгенологическую стадию по Штеинброкеру (SR), затем вычисляют дискриминантную функцию по формуле:F= -1,5506+0,1559·NAD+1,0802·SR-0,0208·VD+0,0163·DM,и в случае, когда F>0, прогнозируют негативную эволюцию ювенильного идеопатического артрита, а когда F<0 - позитивную эволюцию ювенильного идеопатического артрита.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20110123A MD462Z (ru) | 2011-06-30 | 2011-06-30 | Метод прогнозирования эволюции ювенильного идеопатического артрита |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20110123A MD462Z (ru) | 2011-06-30 | 2011-06-30 | Метод прогнозирования эволюции ювенильного идеопатического артрита |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD462Y MD462Y (en) | 2012-01-31 |
| MD462Z true MD462Z (ru) | 2012-08-31 |
Family
ID=45815356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20110123A MD462Z (ru) | 2011-06-30 | 2011-06-30 | Метод прогнозирования эволюции ювенильного идеопатического артрита |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD462Z (ru) |
-
2011
- 2011-06-30 MD MDS20110123A patent/MD462Z/ru not_active IP Right Cessation
Non-Patent Citations (4)
| Title |
|---|
| Minden K., Niewerth M., Listing J., Biedermann T., Bollow M., Schontube M., Zink A. Long-term outcome in patients with juvenile idiopathic artritis. Artritis and Rheum 2002, v.46, p.2392-2401 * |
| Steibrocker O., Traeger CH, Battma RG. Therapeutic criteria in rheumatoid artritis. J Am Med Assoc 1949; nr.140 659-662. * |
| Zak M., Pedersen F.K. Juvenile chronic artritis into adulthood: a long-term follow-up stady. Rheumatology, 2000, v.39, p.198-204 * |
| Новик Г.А., Абакумова Л.Н., Летенкова Н.В., Слизовский Н.В., Слизовская Н.Н. Ювенильные артриты - опыт диагностики и лечения www.lvrach.ru/2008/04/5001010 <http://www.lvrach.ru/2008/04/5001010/> * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD462Y (en) | 2012-01-31 |
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| Date | Code | Title | Description |
|---|---|---|---|
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) |