MD3843715T2 - Terapia infecțiilor cu papilomavirus uman de risc înalt - Google Patents
Terapia infecțiilor cu papilomavirus uman de risc înaltInfo
- Publication number
- MD3843715T2 MD3843715T2 MDE20210608T MDE20210608T MD3843715T2 MD 3843715 T2 MD3843715 T2 MD 3843715T2 MD E20210608 T MDE20210608 T MD E20210608T MD E20210608 T MDE20210608 T MD E20210608T MD 3843715 T2 MD3843715 T2 MD 3843715T2
- Authority
- MD
- Moldova
- Prior art keywords
- acid
- human papillomavirus
- therapy
- composition
- risk human
- Prior art date
Links
- 208000009608 Papillomavirus Infections Diseases 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 241000701806 Human papillomavirus Species 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 abstract 1
- 241000341655 Human papillomavirus type 16 Species 0.000 abstract 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 abstract 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000001630 malic acid Substances 0.000 abstract 1
- 235000011090 malic acid Nutrition 0.000 abstract 1
- 229910017604 nitric acid Inorganic materials 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001850 reproductive effect Effects 0.000 abstract 1
- 229910052711 selenium Inorganic materials 0.000 abstract 1
- 239000011669 selenium Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Reproductive Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Prezenta invenţie se referă la o compoziţie farmaceutică care conţine un compus cu conţinut de seleniu şi un acid acceptabil din punct de vedere farmaceutic, ales dintre acid citric, acid acetic, acid malic, acid carbonic, acid sulfuric, acid azotic, acid clorhidric, acizi din fructe şi amestecuri ale acestora. Această compoziţie este pentru utilizare în prevenirea sau tratamentul unei infecţii a unui organ de reproducere intern al unui pacient de sex feminin cu cel puţin un papilomavirus uman (HPV) ales dintre HPV16, HPV18, HPV31, HPV33 şi HPV58. Compoziţia este aplicată intravaginal.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18191289.0A EP3616693A1 (en) | 2018-08-28 | 2018-08-28 | Therapy of high-risk human papillomavirus infections |
| PCT/EP2019/072926 WO2020043762A1 (en) | 2018-08-28 | 2019-08-28 | Therapy of high-risk human papillomavirus infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD3843715T2 true MD3843715T2 (ro) | 2023-12-31 |
Family
ID=63442535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDE20210608T MD3843715T2 (ro) | 2018-08-28 | 2019-08-28 | Terapia infecțiilor cu papilomavirus uman de risc înalt |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20210299163A1 (ro) |
| EP (2) | EP3616693A1 (ro) |
| JP (1) | JP7420791B2 (ro) |
| CN (1) | CN112584828A (ro) |
| AR (1) | AR116027A1 (ro) |
| AU (1) | AU2019332079A1 (ro) |
| BR (1) | BR112021003360A2 (ro) |
| CA (1) | CA3107691A1 (ro) |
| CL (1) | CL2021000197A1 (ro) |
| EA (1) | EA202190441A1 (ro) |
| ES (1) | ES2958808T3 (ro) |
| GE (1) | GEP20227432B (ro) |
| HR (1) | HRP20231470T1 (ro) |
| HU (1) | HUE064691T2 (ro) |
| IL (1) | IL281080A (ro) |
| MA (1) | MA53482B1 (ro) |
| MD (1) | MD3843715T2 (ro) |
| MX (1) | MX2021002310A (ro) |
| PL (1) | PL3843715T3 (ro) |
| RS (1) | RS64916B1 (ro) |
| TW (1) | TWI827652B (ro) |
| UA (1) | UA127632C2 (ro) |
| WO (1) | WO2020043762A1 (ro) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3875083A1 (en) * | 2020-03-03 | 2021-09-08 | Selo Medical GmbH | Composition for use in a treatment of cervical cell abnormalities comprising selenite compound and acid |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2406377C (en) | 2000-05-10 | 2010-07-06 | Okopharm Forschungs-Und Entwicklungs-Gmbh | Method for reducing the surface area of silicon dioxide |
| AT412758B (de) | 2000-06-05 | 2005-07-25 | Vis Vitalis Lizenz & Handels | Verwendung einer selenithältigen lösung zur behandlung viraler erkrankungen |
| AT412448B (de) | 2001-02-13 | 2005-03-25 | Vis Vitalis Lizenz & Handels | Verwendung von selenhältigen präparaten |
| AT412703B (de) | 2001-12-04 | 2005-06-27 | Vis Vitalis Lizenz & Handels | Verwendung von selenithältigen präparaten zur topischen oder bukkalen anwendung |
| AT511159A1 (de) * | 2011-02-16 | 2012-09-15 | Selo Medical Gmbh | Pharmazeutische zusammensetzungen enthaltend selenit- oder selenathältige verbindungen |
-
2018
- 2018-08-28 EP EP18191289.0A patent/EP3616693A1/en not_active Withdrawn
-
2019
- 2019-08-20 TW TW108129683A patent/TWI827652B/zh active
- 2019-08-28 HR HRP20231470TT patent/HRP20231470T1/hr unknown
- 2019-08-28 PL PL19765421.3T patent/PL3843715T3/pl unknown
- 2019-08-28 AU AU2019332079A patent/AU2019332079A1/en active Pending
- 2019-08-28 CN CN201980055480.2A patent/CN112584828A/zh active Pending
- 2019-08-28 ES ES19765421T patent/ES2958808T3/es active Active
- 2019-08-28 MA MA53482A patent/MA53482B1/fr unknown
- 2019-08-28 MX MX2021002310A patent/MX2021002310A/es unknown
- 2019-08-28 RS RS20231165A patent/RS64916B1/sr unknown
- 2019-08-28 UA UAA202101331A patent/UA127632C2/uk unknown
- 2019-08-28 CA CA3107691A patent/CA3107691A1/en active Pending
- 2019-08-28 MD MDE20210608T patent/MD3843715T2/ro unknown
- 2019-08-28 JP JP2021510859A patent/JP7420791B2/ja active Active
- 2019-08-28 WO PCT/EP2019/072926 patent/WO2020043762A1/en active Application Filing
- 2019-08-28 US US17/264,210 patent/US20210299163A1/en active Pending
- 2019-08-28 GE GEAP201915586A patent/GEP20227432B/en unknown
- 2019-08-28 AR ARP190102447A patent/AR116027A1/es unknown
- 2019-08-28 HU HUE19765421A patent/HUE064691T2/hu unknown
- 2019-08-28 EP EP19765421.3A patent/EP3843715B1/en active Active
- 2019-08-28 BR BR112021003360-2A patent/BR112021003360A2/pt unknown
- 2019-08-28 EA EA202190441A patent/EA202190441A1/ru unknown
-
2021
- 2021-01-25 CL CL2021000197A patent/CL2021000197A1/es unknown
- 2021-02-24 IL IL281080A patent/IL281080A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW202023534A (zh) | 2020-07-01 |
| HRP20231470T1 (hr) | 2024-03-01 |
| MA53482A (fr) | 2021-07-07 |
| IL281080A (en) | 2021-04-29 |
| BR112021003360A2 (pt) | 2021-05-11 |
| JP7420791B2 (ja) | 2024-01-23 |
| UA127632C2 (uk) | 2023-11-08 |
| EP3843715A1 (en) | 2021-07-07 |
| US20210299163A1 (en) | 2021-09-30 |
| MX2021002310A (es) | 2021-04-28 |
| CN112584828A (zh) | 2021-03-30 |
| RS64916B1 (sr) | 2023-12-29 |
| EP3843715C0 (en) | 2023-09-13 |
| HUE064691T2 (hu) | 2024-04-28 |
| TWI827652B (zh) | 2024-01-01 |
| EP3616693A1 (en) | 2020-03-04 |
| CL2021000197A1 (es) | 2021-09-20 |
| EA202190441A1 (ru) | 2021-06-15 |
| ES2958808T3 (es) | 2024-02-15 |
| EP3843715B1 (en) | 2023-09-13 |
| AR116027A1 (es) | 2021-03-25 |
| JP2021536454A (ja) | 2021-12-27 |
| AU2019332079A1 (en) | 2021-02-11 |
| CA3107691A1 (en) | 2020-03-05 |
| WO2020043762A1 (en) | 2020-03-05 |
| GEP20227432B (en) | 2022-10-25 |
| MA53482B1 (fr) | 2023-11-30 |
| PL3843715T3 (pl) | 2024-02-19 |
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