MD266C2 - Process for preparation of 5-haloid thienoisothiazole-3(2H)-on-1,1-dioxides derivatives - Google Patents

Process for preparation of 5-haloid thienoisothiazole-3(2H)-on-1,1-dioxides derivatives

Info

Publication number
MD266C2
MD266C2 MD94-0300A MD940300A MD266C2 MD 266 C2 MD266 C2 MD 266C2 MD 940300 A MD940300 A MD 940300A MD 266 C2 MD266 C2 MD 266C2
Authority
MD
Moldova
Prior art keywords
haloid
dioxides
derivatives
preparation
formulawhere
Prior art date
Application number
MD94-0300A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD266B1 (en
Inventor
Dieter Binder
Frantz Rovenszky
Original Assignee
Chemisch Pharmazeutische Forschungsgesellschaft M.B.H.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT88390A external-priority patent/ATA39088A/en
Application filed by Chemisch Pharmazeutische Forschungsgesellschaft M.B.H. filed Critical Chemisch Pharmazeutische Forschungsgesellschaft M.B.H.
Publication of MD266B1 publication Critical patent/MD266B1/en
Publication of MD266C2 publication Critical patent/MD266C2/en

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

The invention relates to the heterocyclic materials and, particularly, to the preparation of the 5-haloid theienoisothiazoles-3-(2H)-on-1,1-dioxides derivatives or pharmaceutically supportable acidic additive salts of formulawhere R is haloid, possessing the anxiolytic activity, which may be used in the medicine.The aim of the invention - cleation of new more active substances of the indicated class. the syntehesis is conductes by the reaction of 1-(2-pyrimidinylpiperazine with the compound of formulawhere X - haloid in the absolute dimetilhylformamide medium at 60°C during 45 min at further desired product isolation in the free form or in the form of the required salt. The new materials are low-toxic (more then 2000 mg/kg) and possesse a high antxiolytic activity.
MD94-0300A 1988-02-18 1994-09-14 Process for preparation of 5-haloid thienoisothiazole-3(2H)-on-1,1-dioxides derivatives MD266C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT88390A ATA39088A (en) 1988-02-18 1988-02-18 BASICALLY SUBSTITUTED THIENOISOTHIAZOL-3 (2H) -ON-1,1-DIOXIDES AND THEIR PHARMACEUTICALLY COMPATIBLE SALTS, METHOD FOR THE PRODUCTION AND THEIR USE
SU894613473A SU1729293A3 (en) 1988-02-18 1989-02-17 Method for preparation derivatives of 5-haloid tienoisothiazole-3 (2 h)-oh-1,1 dioxides

Publications (2)

Publication Number Publication Date
MD266B1 MD266B1 (en) 1995-08-31
MD266C2 true MD266C2 (en) 1995-12-31

Family

ID=25592550

Family Applications (1)

Application Number Title Priority Date Filing Date
MD94-0300A MD266C2 (en) 1988-02-18 1994-09-14 Process for preparation of 5-haloid thienoisothiazole-3(2H)-on-1,1-dioxides derivatives

Country Status (2)

Country Link
LV (1) LV5521A3 (en)
MD (1) MD266C2 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Brevet nr. 0220051, EP, Int. cl. C 07 D 417/14, 1987. *

Also Published As

Publication number Publication date
LV5521A3 (en) 1994-03-10
MD266B1 (en) 1995-08-31

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