MA54223A - 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDIN-1-ONE DERIVATIVES USED AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER - Google Patents

2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDIN-1-ONE DERIVATIVES USED AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER

Info

Publication number
MA54223A
MA54223A MA054223A MA54223A MA54223A MA 54223 A MA54223 A MA 54223A MA 054223 A MA054223 A MA 054223A MA 54223 A MA54223 A MA 54223A MA 54223 A MA54223 A MA 54223A
Authority
MA
Morocco
Prior art keywords
pyrrolo
pyridin
dihydro
cancer
treatment
Prior art date
Application number
MA054223A
Other languages
French (fr)
Other versions
MA54223B1 (en
Inventor
Omar Khaled Ahmad
Bel Matthew L Del
Rebecca Anne Gallego
Mingying He
Mehran Jalaie
Ted William Johnson
Robert Steven Kania
Michele Ann Mctigue
Sajiv Krishnan Nair
Anne-Marie Dechert Schmitt
Jamison Bryce Tuttle
Dahui Zhou
Ru Zhou
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority claimed from PCT/IB2019/059702 external-priority patent/WO2020100027A1/en
Publication of MA54223A publication Critical patent/MA54223A/en
Publication of MA54223B1 publication Critical patent/MA54223B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA54223A 2018-11-15 2019-11-12 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDIN-1-ONE DERIVATIVES AS HPK1 INHIBITORS FOR CANCER TREATMENT MA54223B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862767602P 2018-11-15 2018-11-15
PCT/IB2019/059702 WO2020100027A1 (en) 2018-11-15 2019-11-12 2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-one derivatives as hpk1 inhibitors for the treatment of cancer

Publications (2)

Publication Number Publication Date
MA54223A true MA54223A (en) 2022-02-23
MA54223B1 MA54223B1 (en) 2023-10-31

Family

ID=77369712

Family Applications (1)

Application Number Title Priority Date Filing Date
MA54223A MA54223B1 (en) 2018-11-15 2019-11-12 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDIN-1-ONE DERIVATIVES AS HPK1 INHIBITORS FOR CANCER TREATMENT

Country Status (2)

Country Link
AR (1) AR117073A1 (en)
MA (1) MA54223B1 (en)

Also Published As

Publication number Publication date
AR117073A1 (en) 2021-07-07
MA54223B1 (en) 2023-10-31

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