MA53129A - Inhibiteurs de l'histone désacétylase - Google Patents
Inhibiteurs de l'histone désacétylaseInfo
- Publication number
- MA53129A MA53129A MA053129A MA53129A MA53129A MA 53129 A MA53129 A MA 53129A MA 053129 A MA053129 A MA 053129A MA 53129 A MA53129 A MA 53129A MA 53129 A MA53129 A MA 53129A
- Authority
- MA
- Morocco
- Prior art keywords
- histone deacetylase
- deacetylase inhibitors
- inhibitors
- histone
- deacetylase
- Prior art date
Links
- 229940121372 histone deacetylase inhibitor Drugs 0.000 title 1
- 239000003276 histone deacetylase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862697498P | 2018-07-13 | 2018-07-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA53129A true MA53129A (fr) | 2021-05-19 |
Family
ID=67480370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA053129A MA53129A (fr) | 2018-07-13 | 2019-07-12 | Inhibiteurs de l'histone désacétylase |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20210276978A1 (fr) |
| EP (1) | EP3820859B1 (fr) |
| JP (2) | JP7414820B2 (fr) |
| KR (1) | KR20210031704A (fr) |
| CN (1) | CN112424184A (fr) |
| AR (1) | AR115768A1 (fr) |
| AU (1) | AU2019300036A1 (fr) |
| CA (1) | CA3106355A1 (fr) |
| EA (1) | EA202190077A1 (fr) |
| IL (2) | IL279940B2 (fr) |
| MA (1) | MA53129A (fr) |
| MX (1) | MX2021000468A (fr) |
| SG (1) | SG11202012916WA (fr) |
| TW (1) | TWI809146B (fr) |
| WO (1) | WO2020014605A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS62639B1 (sr) | 2015-07-06 | 2021-12-31 | Alkermes Inc | Hetero-halo inhibitori histonskih deacetilaza |
| RS62959B1 (sr) | 2017-01-11 | 2022-03-31 | Alkermes Inc | Biciklični inhibitori histon-deacetilaze |
| MD3664802T2 (ro) | 2017-08-07 | 2022-07-31 | Alkermes Inc | Inhibitori biciclici ai deacetilazei histonei |
| CA3240229A1 (fr) | 2021-12-03 | 2023-06-08 | Tango Therapeutics, Inc. | Nouveaux inhibiteurs de hdac et leur utilisation therapeutique |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008271170A1 (en) * | 2007-06-27 | 2009-01-08 | Merck Sharp & Dohme Corp. | Pyridyl and pyrimidinyl derivatives as histone deacetylase inhibitors |
| JP6240063B2 (ja) * | 2011-04-28 | 2017-11-29 | ザ ブロード インスティテュート， インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
| WO2016018795A1 (fr) * | 2014-07-28 | 2016-02-04 | The General Hospital Corporation | Inhibiteurs d'histone désacétylase |
| RS62639B1 (sr) * | 2015-07-06 | 2021-12-31 | Alkermes Inc | Hetero-halo inhibitori histonskih deacetilaza |
| TWI794171B (zh) * | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| CA3043618A1 (fr) * | 2016-11-23 | 2018-05-31 | Regenacy Pharmaceuticals, Llc | Derives piperazine en tant qu'inhibiteurs selectifs de hdac1,2 |
-
2019
- 2019-07-12 MA MA053129A patent/MA53129A/fr unknown
- 2019-07-12 EP EP19746301.1A patent/EP3820859B1/fr active Active
- 2019-07-12 IL IL279940A patent/IL279940B2/en unknown
- 2019-07-12 US US17/260,193 patent/US20210276978A1/en not_active Abandoned
- 2019-07-12 MX MX2021000468A patent/MX2021000468A/es unknown
- 2019-07-12 KR KR1020217002884A patent/KR20210031704A/ko not_active Application Discontinuation
- 2019-07-12 CN CN201980046820.5A patent/CN112424184A/zh active Pending
- 2019-07-12 AR ARP190101972A patent/AR115768A1/es unknown
- 2019-07-12 TW TW108124686A patent/TWI809146B/zh active
- 2019-07-12 IL IL309951A patent/IL309951A/en unknown
- 2019-07-12 EA EA202190077A patent/EA202190077A1/ru unknown
- 2019-07-12 JP JP2021523578A patent/JP7414820B2/ja active Active
- 2019-07-12 CA CA3106355A patent/CA3106355A1/fr active Pending
- 2019-07-12 SG SG11202012916WA patent/SG11202012916WA/en unknown
- 2019-07-12 WO PCT/US2019/041592 patent/WO2020014605A1/fr unknown
- 2019-07-12 AU AU2019300036A patent/AU2019300036A1/en active Pending
-
2023
- 2023-12-28 JP JP2023222406A patent/JP2024038202A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP7414820B2 (ja) | 2024-01-16 |
| AU2019300036A1 (en) | 2021-01-14 |
| IL279940B2 (en) | 2024-06-01 |
| IL279940B1 (en) | 2024-02-01 |
| JP2021531336A (ja) | 2021-11-18 |
| SG11202012916WA (en) | 2021-01-28 |
| MX2021000468A (es) | 2021-06-23 |
| KR20210031704A (ko) | 2021-03-22 |
| TW202019903A (zh) | 2020-06-01 |
| CA3106355A1 (fr) | 2020-01-16 |
| CN112424184A (zh) | 2021-02-26 |
| AR115768A1 (es) | 2021-02-24 |
| IL309951A (en) | 2024-03-01 |
| WO2020014605A1 (fr) | 2020-01-16 |
| EA202190077A1 (ru) | 2021-08-30 |
| TWI809146B (zh) | 2023-07-21 |
| EP3820859C0 (fr) | 2024-03-20 |
| EP3820859A1 (fr) | 2021-05-19 |
| IL279940A (en) | 2021-03-01 |
| US20210276978A1 (en) | 2021-09-09 |
| EP3820859B1 (fr) | 2024-03-20 |
| JP2024038202A (ja) | 2024-03-19 |
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