MA52220B1 - Composés hétérocycliques utilisés comme immunomodulateurs - Google Patents

Composés hétérocycliques utilisés comme immunomodulateurs

Info

Publication number
MA52220B1
MA52220B1 MA52220A MA52220A MA52220B1 MA 52220 B1 MA52220 B1 MA 52220B1 MA 52220 A MA52220 A MA 52220A MA 52220 A MA52220 A MA 52220A MA 52220 B1 MA52220 B1 MA 52220B1
Authority
MA
Morocco
Prior art keywords
immunomodulators
compounds used
heterocyclic compounds
compounds
alleviation
Prior art date
Application number
MA52220A
Other languages
English (en)
Other versions
MA52220A (fr
Inventor
Liangxing Wu
Wenqing Yao
Jingwei Li
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Priority claimed from PCT/US2019/025036 external-priority patent/WO2019191707A1/fr
Publication of MA52220A publication Critical patent/MA52220A/fr
Publication of MA52220B1 publication Critical patent/MA52220B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne des composés de formule (i'), des procédés d'utilisation de ces composés en tant qu'immunomodulateurs, et des compositions pharmaceutiques comprenant de tels composés. Lesdits composés sont utiles dans le traitement, la prévention ou l'atténuation de maladies ou de troubles tels que le cancer ou les infections.
MA52220A 2018-03-30 2019-03-29 Composés hétérocycliques utilisés comme immunomodulateurs MA52220B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862650821P 2018-03-30 2018-03-30
PCT/US2019/025036 WO2019191707A1 (fr) 2018-03-30 2019-03-29 Composés hétérocycliques utilisés comme immunomodulateurs

Publications (2)

Publication Number Publication Date
MA52220A MA52220A (fr) 2021-02-17
MA52220B1 true MA52220B1 (fr) 2022-12-30

Family

ID=74446255

Family Applications (1)

Application Number Title Priority Date Filing Date
MA52220A MA52220B1 (fr) 2018-03-30 2019-03-29 Composés hétérocycliques utilisés comme immunomodulateurs

Country Status (2)

Country Link
AR (1) AR115314A1 (fr)
MA (1) MA52220B1 (fr)

Also Published As

Publication number Publication date
AR115314A1 (es) 2020-12-23
MA52220A (fr) 2021-02-17

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