MA48461A - Excipients pour réduire la viscosité de formulations d'anticorps et compositions de formulation - Google Patents
Excipients pour réduire la viscosité de formulations d'anticorps et compositions de formulationInfo
- Publication number
- MA48461A MA48461A MA048461A MA48461A MA48461A MA 48461 A MA48461 A MA 48461A MA 048461 A MA048461 A MA 048461A MA 48461 A MA48461 A MA 48461A MA 48461 A MA48461 A MA 48461A
- Authority
- MA
- Morocco
- Prior art keywords
- excipients
- viscosity
- reduce
- antibody formulations
- formulation compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762492049P | 2017-04-28 | 2017-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA48461A true MA48461A (fr) | 2020-03-04 |
Family
ID=62148500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA048461A MA48461A (fr) | 2017-04-28 | 2018-04-24 | Excipients pour réduire la viscosité de formulations d'anticorps et compositions de formulation |
Country Status (4)
Country | Link |
---|---|
US (1) | US20200352857A1 (fr) |
EP (1) | EP3615065A1 (fr) |
MA (1) | MA48461A (fr) |
WO (1) | WO2018200533A1 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109439536A (zh) * | 2017-08-18 | 2019-03-08 | 黄国仁 | 饮用水细菌快速培养装置及菌落总数快速检测系统 |
US20220275073A1 (en) * | 2019-08-12 | 2022-09-01 | Amgen Inc. | Anti-Sclerostin Antibody Formulations |
BR112022016456A2 (pt) * | 2020-02-18 | 2022-10-04 | Amgen Inc | Formulações de anticorpos anti-tslp humanos e métodos de uso dos mesmos |
CA3187322A1 (fr) * | 2020-07-13 | 2022-01-20 | Merck Patent Gmbh | Excipients reducteurs de viscosite et leurs combinaisons pour formulations de proteines hautement concentrees |
WO2023140807A1 (fr) * | 2022-01-19 | 2023-07-27 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Compositions pharmaceutiques de trastuzumab |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
EP0173494A3 (fr) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Récepteurs chimériques par liaison et expression de l'ADN |
GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
CA2050918A1 (fr) | 1990-01-12 | 1991-07-13 | Raju Kucherlapati | Production d'anticorps xenogeniques |
WO2004039337A2 (fr) | 2002-10-31 | 2004-05-13 | Protein Design Labs, Inc. | Formulations pharmaceutiques liquides stables d'anticorps ayant tendance a l'isomerisation |
EA012801B1 (ru) | 2005-06-14 | 2009-12-30 | Эмджен Инк. | Самобуферирующиеся композиции белков |
AR080428A1 (es) * | 2010-01-20 | 2012-04-11 | Chugai Pharmaceutical Co Ltd | Formulaciones liquidas estabilizadas contentivas de anticuerpos |
CN102958538A (zh) * | 2010-05-03 | 2013-03-06 | 弗·哈夫曼-拉罗切有限公司 | 用于降低含有蛋白质的制剂的粘度的组合物和方法 |
KR101673654B1 (ko) * | 2011-04-20 | 2016-11-07 | 산도즈 아게 | 융합 단백질 TNFR:Fc의 안정한 제약 액체 제제 |
BR112014010186A2 (pt) | 2011-10-28 | 2017-05-02 | Integritybio Inc | formulação farmacêutica estável, kit, composição farmacêutica, método para preparar uma formulação farmacêutica, e, método para tratar um humano ou animal |
SG10201806539XA (en) * | 2013-09-11 | 2018-08-30 | Eagle Biologics Inc | Liquid protein formulations containing ionic liquids |
US20160074515A1 (en) * | 2014-06-20 | 2016-03-17 | Reform Biologics, Llc | Viscosity-reducing excipient compounds for protein formulations |
EP3169710A1 (fr) * | 2014-07-14 | 2017-05-24 | Amgen Inc. | Formulations d'anticorps cristallins |
MX2017005243A (es) | 2014-10-23 | 2017-08-18 | Amgen Inc | Reducción de la viscosidad de formulaciones farmacéuticas. |
-
2018
- 2018-04-24 US US16/609,448 patent/US20200352857A1/en active Pending
- 2018-04-24 MA MA048461A patent/MA48461A/fr unknown
- 2018-04-24 WO PCT/US2018/029156 patent/WO2018200533A1/fr active Application Filing
- 2018-04-24 EP EP18724055.1A patent/EP3615065A1/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
US20200352857A1 (en) | 2020-11-12 |
EP3615065A1 (fr) | 2020-03-04 |
WO2018200533A1 (fr) | 2018-11-01 |
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