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Application filed by Omeros Corp, Univ LeicesterfiledCriticalOmeros Corp
Priority claimed from PCT/US2016/061113external-prioritypatent/WO2017083371A1/en
Publication of MA42711A1publicationCriticalpatent/MA42711A1/en
Publication of MA42711B1publicationCriticalpatent/MA42711B1/en
Medicines Containing Material From Animals Or Micro-Organisms
(AREA)
Abstract
Selon un aspect, l'invention concerne des méthodes d'inhibition des effets de l'activation du complément dépendant de masp-2 chez un sujet humain souffrant de tma associée à une greffe de cellules souches hématopoïétiques. Les méthodes comprennent l'étape d'administration, à un sujet qui en a besoin, d'une quantité d'un agent inhibiteur de masp-2 efficace pour inhiber l'activation du complément dépendant de masp-2.In one aspect, the invention relates to methods of inhibiting the effects of activation of masp-2 dependent complement in a human subject with tma associated with hematopoietic stem cell transplantation. The methods include the step of administering, to a subject in need thereof, an amount of a masp-2 inhibitory agent effective to inhibit activation of masp-2 dependent complement.
MA42711A2015-11-092016-11-09
Methods of treating pathological conditions associated with activation of masp-2-dependent complement
MA42711B1
(en)
VICINAL PRIMARY DIAMINS ASSOCIATED WITH CHELATING MOTIFS OF METALS AND / OR FREE RADICALS, ACTIVE AGAINST CARBONYL AND OXIDIZING STRESSES AND THEIR USE