MA42264A - Procédé de préparation d'oltipraz - Google Patents
Procédé de préparation d'oltiprazInfo
- Publication number
- MA42264A MA42264A MA042264A MA42264A MA42264A MA 42264 A MA42264 A MA 42264A MA 042264 A MA042264 A MA 042264A MA 42264 A MA42264 A MA 42264A MA 42264 A MA42264 A MA 42264A
- Authority
- MA
- Morocco
- Prior art keywords
- oltipraz
- preparation process
- preparation
- oltipraz preparation
- Prior art date
Links
- CKNAQFVBEHDJQV-UHFFFAOYSA-N oltipraz Chemical compound S1SC(=S)C(C)=C1C1=CN=CC=N1 CKNAQFVBEHDJQV-UHFFFAOYSA-N 0.000 title 1
- 229950008687 oltipraz Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1891DE2015 | 2015-06-25 | ||
| US14/823,256 US20160376259A1 (en) | 2015-06-25 | 2015-08-11 | Methods for Preparing Oltipraz |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA42264A true MA42264A (fr) | 2018-05-02 |
Family
ID=57601888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA042264A MA42264A (fr) | 2015-06-25 | 2016-06-24 | Procédé de préparation d'oltipraz |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20160376259A1 (fr) |
| EP (1) | EP3313835A4 (fr) |
| JP (1) | JP6773693B2 (fr) |
| KR (1) | KR20180022838A (fr) |
| AU (1) | AU2016283082B2 (fr) |
| CA (1) | CA2989228A1 (fr) |
| MA (1) | MA42264A (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160376259A1 (en) | 2015-06-25 | 2016-12-29 | St Ip Holding Ag | Methods for Preparing Oltipraz |
| CN109996563A (zh) * | 2016-09-12 | 2019-07-09 | St知识产权控股公司 | 4-甲基-5-(吡嗪-2-基)-3h-1,2-二硫杂环戊烯-3-硫酮的制剂、味道改良的制剂及其制备和使用方法 |
| JP2019531344A (ja) * | 2016-09-12 | 2019-10-31 | エスティー アイピー ホールディング エージー | ４−メチル−５−（ピラジン−２−イル）−３ｈ−１，２−ジチオール−３−チオンの処方物、ならびにそれらの製造方法及び使用方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL171985C (nl) * | 1976-02-10 | 1983-06-16 | Rhone Poulenc Ind | Werkwijze voor het bereiden van preparaten met werking tegen schistosomiasis, de aldus verkregen gevormde preparaten en werkwijze voor het bereiden van 1,2-dithioolverbindingen. |
| WO2001009118A2 (fr) * | 1999-07-29 | 2001-02-08 | Patrick T Prendergast | Composes dithiolthione pour le traitement de troubles neurologiques et pour renforcer la memoire |
| CA2404915A1 (fr) | 2000-04-07 | 2001-10-18 | Sang Geon Kim | Utilisation prophylactique et therapeutique d'oltipraz en tant qu'agent anti-fibrotique et anti-cirrhotique dans le foie et composition pharmaceutique contenant de l'oltipraz |
| ATE540586T1 (de) * | 2000-11-20 | 2012-01-15 | Applied Food Sciences Inc | Verfahren zur erhöhung des gehalts an zuträglichen verbindungen nach der verarbeitung in getränken, in denen diese verbindungen natürlich vorkommen |
| KR100491318B1 (ko) * | 2002-11-26 | 2005-05-24 | 씨제이 주식회사 | 올티프라즈(Ｏｌｔｉｐｒａｚ) 제조방법 |
| KR100629771B1 (ko) | 2004-01-27 | 2006-09-28 | 씨제이 주식회사 | 결정성이 감소되거나 무정형화된 올티프라즈의 제조방법 |
| US20160376259A1 (en) | 2015-06-25 | 2016-12-29 | St Ip Holding Ag | Methods for Preparing Oltipraz |
-
2015
- 2015-08-11 US US14/823,256 patent/US20160376259A1/en not_active Abandoned
-
2016
- 2016-06-24 AU AU2016283082A patent/AU2016283082B2/en not_active Ceased
- 2016-06-24 CA CA2989228A patent/CA2989228A1/fr not_active Abandoned
- 2016-06-24 JP JP2017565999A patent/JP6773693B2/ja not_active Expired - Fee Related
- 2016-06-24 KR KR1020187002139A patent/KR20180022838A/ko not_active Ceased
- 2016-06-24 EP EP16813869.1A patent/EP3313835A4/fr not_active Withdrawn
- 2016-06-24 MA MA042264A patent/MA42264A/fr unknown
-
2018
- 2018-07-20 US US16/041,282 patent/US20190084971A1/en not_active Abandoned
-
2020
- 2020-02-07 US US16/784,915 patent/US20200172522A1/en not_active Abandoned
- 2020-04-21 US US16/854,480 patent/US10968207B2/en active Active
-
2021
- 2021-03-23 US US17/210,049 patent/US20210206752A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20210206752A1 (en) | 2021-07-08 |
| US20200247791A1 (en) | 2020-08-06 |
| US20160376259A1 (en) | 2016-12-29 |
| US20200172522A1 (en) | 2020-06-04 |
| EP3313835A2 (fr) | 2018-05-02 |
| AU2016283082A1 (en) | 2018-01-18 |
| CA2989228A1 (fr) | 2016-12-29 |
| AU2016283082B2 (en) | 2020-11-26 |
| KR20180022838A (ko) | 2018-03-06 |
| JP6773693B2 (ja) | 2020-10-21 |
| JP2018520134A (ja) | 2018-07-26 |
| US20190084971A1 (en) | 2019-03-21 |
| US10968207B2 (en) | 2021-04-06 |
| EP3313835A4 (fr) | 2019-01-09 |
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