MA40255A - Production d'acide lysergique par modification génétique d'un champignon - Google Patents
Production d'acide lysergique par modification génétique d'un champignonInfo
- Publication number
- MA40255A MA40255A MA040255A MA40255A MA40255A MA 40255 A MA40255 A MA 40255A MA 040255 A MA040255 A MA 040255A MA 40255 A MA40255 A MA 40255A MA 40255 A MA40255 A MA 40255A
- Authority
- MA
- Morocco
- Prior art keywords
- fungus
- genetic modification
- production
- lysergic acid
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Botany (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La présente invention concerne un procédé de production d'acide lysergique et d'autres alcaloïdes de l'ergot de seigle par modification génétique d'un champignon. L'invention concerne une souche de champignon correspondant, par exemple, à
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462012658P | 2014-06-16 | 2014-06-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA40255A true MA40255A (fr) | 2017-04-19 |
Family
ID=54835653
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA040255A MA40255A (fr) | 2014-06-16 | 2015-06-15 | Production d'acide lysergique par modification génétique d'un champignon |
Country Status (4)
Country | Link |
---|---|
US (2) | US9790528B2 (fr) |
EP (1) | EP3155093A4 (fr) |
MA (1) | MA40255A (fr) |
WO (1) | WO2015195535A2 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA40255A (fr) * | 2014-06-16 | 2017-04-19 | Univ West Virginia | Production d'acide lysergique par modification génétique d'un champignon |
US20230135464A1 (en) * | 2019-09-12 | 2023-05-04 | The Trustees Of Dartmouth College | Compositions and methods related to fungal hypoxia responsive morphology factor a (hrma) and biofilm architecture factor (baf) proteins |
CN113652443B (zh) * | 2021-08-05 | 2023-06-06 | 中国科学院微生物研究所 | 菌株及其发酵生产麦角生物碱的应用 |
WO2023096577A2 (fr) * | 2021-11-26 | 2023-06-01 | National University Of Singapore | Production d'acide d-lysergique |
CN115125260B (zh) * | 2022-05-27 | 2023-05-26 | 北京大学现代农业研究院 | 一种匍柄霉聚酮合成酶基因pks1及应用 |
CN116024107B (zh) * | 2022-08-04 | 2023-10-03 | 中国科学院青岛生物能源与过程研究所 | 一种产麦角酸的工程菌及其构建方法与应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1067513A (en) | 1963-08-29 | 1967-05-03 | Sandoz Ltd | Derivatives of ergolene |
JP2015530879A (ja) * | 2012-08-22 | 2015-10-29 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | クラビン類アルカロイドを製造するための遺伝子およびプロセス |
MA40255A (fr) * | 2014-06-16 | 2017-04-19 | Univ West Virginia | Production d'acide lysergique par modification génétique d'un champignon |
-
2015
- 2015-06-15 MA MA040255A patent/MA40255A/fr unknown
- 2015-06-15 US US14/739,382 patent/US9790528B2/en not_active Expired - Fee Related
- 2015-06-15 EP EP15810268.1A patent/EP3155093A4/fr not_active Withdrawn
- 2015-06-15 WO PCT/US2015/035784 patent/WO2015195535A2/fr active Application Filing
-
2017
- 2017-09-11 US US15/700,598 patent/US10370689B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP3155093A4 (fr) | 2018-02-21 |
US9790528B2 (en) | 2017-10-17 |
WO2015195535A2 (fr) | 2015-12-23 |
US20150361471A1 (en) | 2015-12-17 |
US10370689B2 (en) | 2019-08-06 |
WO2015195535A3 (fr) | 2016-02-18 |
US20170369915A1 (en) | 2017-12-28 |
EP3155093A2 (fr) | 2017-04-19 |
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