MA38685A1 - Providing a pharmacokinetic drug dosing regimen - Google Patents

Providing a pharmacokinetic drug dosing regimen

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Publication number
MA38685A1
MA38685A1 MA38685A MA38685A MA38685A1 MA 38685 A1 MA38685 A1 MA 38685A1 MA 38685 A MA38685 A MA 38685A MA 38685 A MA38685 A MA 38685A MA 38685 A1 MA38685 A1 MA 38685A1
Authority
MA
Morocco
Prior art keywords
dosing regimen
providing
plasma protein
therapeutic plasma
dosing
Prior art date
Application number
MA38685A
Other languages
French (fr)
Other versions
MA38685B2 (en
Inventor
Alexandra Loew-Baselli
Gerald Dickey Spotts
Myungshin Oh
Original Assignee
Baxalta Inc
Baxalta GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta Inc, Baxalta GmbH filed Critical Baxalta Inc
Priority claimed from PCT/US2014/043517 external-priority patent/WO2015006033A1/en
Publication of MA38685A1 publication Critical patent/MA38685A1/en
Publication of MA38685B2 publication Critical patent/MA38685B2/en

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Abstract

L'invention porte sur un système et un procédé permettant d'assurer un régime de dosage de protéines plasmatiques thérapeutiques, comprenant la détermination d'un profil pharmacocinétique d'un patient à l'aide d'un modèle bayesien de profils pharmacocinétiques de patients prélevés. Le système et le procédé pour exemple comprennent également la détermination d'un premier régime de dosage pour un premier intervalle de dosage spécifié comprenant (i) un premier dosage et (ii) un premier taux de protéines plasmatiques thérapeutiques chez le patient sur une période de temps sur la base au moins du profil pharmacocinétique et la détermination d'un second régime de dosage pour un second intervalle de dosage spécifié comprenant (i) un second dosage et (ii) un second taux de protéines plasmatiques thérapeutiques chez le patient sur la période de temps sur la base au moins du profil pharmacocinétique. Le système et le procédé pour exemple comprennent en outre l'affichage du premier régime de dosage et du second régime de dosage sur un dispositif client de façon à ce que le premier régime de dosage soit affiché conjointement avec le second régime de dosage.A system and method for providing a therapeutic plasma protein assay regime, comprising determining a pharmacokinetic profile of a patient using a Bayesian model of pharmacokinetic profiles of patients sampled . The exemplary system and method also includes determining a first dosing regimen for a first specified dosing interval comprising (i) a first dosage and (ii) a first therapeutic plasma protein level in the patient over a period of time. at least on the basis of the pharmacokinetic profile and the determination of a second dosing regimen for a second specified dosing interval comprising (i) a second assay and (ii) a second therapeutic plasma protein level in the patient over the period time based on at least the pharmacokinetic profile. The exemplary system and method further includes displaying the first dosing regimen and the second dosing regimen on a client device so that the first dosing regimen is displayed together with the second dosing regimen.

MA38685A 2013-06-20 2014-06-20 Provision of a pharmacokinetic drug dosing regimen MA38685B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361837421P 2013-06-20 2013-06-20
PCT/US2014/043517 WO2015006033A1 (en) 2013-06-20 2014-06-20 Providing a pharmacokinetic drug dosing regime

Publications (2)

Publication Number Publication Date
MA38685A1 true MA38685A1 (en) 2017-10-31
MA38685B2 MA38685B2 (en) 2020-05-29

Family

ID=60765491

Family Applications (1)

Application Number Title Priority Date Filing Date
MA38685A MA38685B2 (en) 2013-06-20 2014-06-20 Provision of a pharmacokinetic drug dosing regimen

Country Status (1)

Country Link
MA (1) MA38685B2 (en)

Also Published As

Publication number Publication date
MA38685B2 (en) 2020-05-29

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