MA38473B1 - (2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (substituted benzyl-cyano-methyl) -amides used as inhibitors of - Google Patents
(2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (substituted benzyl-cyano-methyl) -amides used as inhibitors ofInfo
- Publication number
- MA38473B1 MA38473B1 MA38473A MA38473A MA38473B1 MA 38473 B1 MA38473 B1 MA 38473B1 MA 38473 A MA38473 A MA 38473A MA 38473 A MA38473 A MA 38473A MA 38473 B1 MA38473 B1 MA 38473B1
- Authority
- MA
- Morocco
- Prior art keywords
- aza
- bicyclo
- heptane
- cyano
- inhibitors
- Prior art date
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La présente invention concerne des (benzyl-cyano-méthyl)-amides de l'acide 2-aza-bicyclo[2.2.1]heptane-3-carboxylique de formule (1) et leur utilisation comme inhibiteurs de la cathépsine c, des compositions pharmaceutiques contenant ceux-ci, et des méthodes d'utilisation de ceux-ci comme agents pour le traitement et/ou la prévention de maladies associées à l'activité de la dipeptidyl peptidase i, par exemple des maladies respiratoires.The present invention relates to (benzyl-cyano-methyl) -amides of 2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid of formula (1) and their use as cathepsin-c inhibitors, compositions pharmaceutical compositions containing these, and methods of use thereof as agents for the treatment and / or prevention of diseases associated with the activity of dipeptidyl peptidase i, for example respiratory diseases.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13159240 | 2013-03-14 | ||
PCT/EP2014/054794 WO2014140075A1 (en) | 2013-03-14 | 2014-03-12 | Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c |
Publications (2)
Publication Number | Publication Date |
---|---|
MA38473A1 MA38473A1 (en) | 2016-04-29 |
MA38473B1 true MA38473B1 (en) | 2016-11-30 |
Family
ID=47845866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA38473A MA38473B1 (en) | 2013-03-14 | 2015-10-09 | (2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (substituted benzyl-cyano-methyl) -amides used as inhibitors of |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR095376A1 (en) |
MA (1) | MA38473B1 (en) |
-
2014
- 2014-03-12 AR ARP140100916A patent/AR095376A1/en unknown
-
2015
- 2015-10-09 MA MA38473A patent/MA38473B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
AR095376A1 (en) | 2015-10-14 |
MA38473A1 (en) | 2016-04-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH12015501964A1 (en) | Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c | |
MA38483A1 (en) | Inhibitors of ido | |
MA38380A1 (en) | Quinazoline inhibitors of activation of mutant forms of epidermal growth receptor (EGFR) | |
MA37762A1 (en) | N-aryltriazole compounds used as antagonists of lpar | |
MA44948A1 (en) | Bace 1 inhibitors | |
MA35459B1 (en) | Compounds and compositions that can be used as c-kit kinase inhibitors | |
MA37764A1 (en) | N-alkyltriazole compounds used as antagonists of lpar | |
TR201904614T4 (en) | Novel pyrazole derivative. | |
MA41179A (en) | PARG INHIBITOR COMPOUNDS | |
MA39219B1 (en) | New lrrk2 Kinase Inhibitor Compounds Used to Treat Parkinson's, Alzheimer's and Amyotrophic Lateral Sclerosis | |
MA35638B1 (en) | 2-thiopyrimidinones | |
MA38810B1 (en) | Inhibitors of rorc2 related methods of use | |
MA37691B1 (en) | 5-amino [1,4] thiazines as bace1 inhibitors | |
MA37763B1 (en) | Difluoro-hexahydro-cyclopentaoxazinyl and difluoro-hexahydro-benzooxazinyls as bace1 inhibitors | |
MA37765A1 (en) | Substituted pyrazole compounds used as lpar antagonists | |
MA43052B1 (en) | Human Plasma Kallikrein Inhibitors | |
MA38473B1 (en) | (2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (substituted benzyl-cyano-methyl) -amides used as inhibitors of | |
MA35010B1 (en) | INHIBITORS OF PEPTIDE DEFORMYLASE | |
MA39260A1 (en) | (2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (substituted benzyl-cyano-methyl) -amides used as inhibitors of | |
MA39533B1 (en) | Compounds, pharmaceutical composition and their use in the treatment of neurodegenerative diseases | |
MA56098B1 (en) | HETEROCYCLIC IMMUNOMODULATORS AS WELL AS PDL1 INHIBITORS | |
MA43263B1 (en) | Heterocyclic compounds used as immunomodulators | |
MA45867B1 (en) | Estrogen receptor modulators | |
MA44144B1 (en) | Heterocyclic compounds used as immunomodulators | |
MA43103B1 (en) | Macrocyclic peptides against acetinobacter baumannii |