MA44144B1 - Heterocyclic compounds used as immunomodulators - Google Patents
Heterocyclic compounds used as immunomodulatorsInfo
- Publication number
- MA44144B1 MA44144B1 MA44144A MA44144A MA44144B1 MA 44144 B1 MA44144 B1 MA 44144B1 MA 44144 A MA44144 A MA 44144A MA 44144 A MA44144 A MA 44144A MA 44144 B1 MA44144 B1 MA 44144B1
- Authority
- MA
- Morocco
- Prior art keywords
- immunomodulators
- compounds used
- heterocyclic compounds
- compounds
- alleviation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des composés de formule (i'), des méthodes d'utilisation de ces composés comme immunomodulateurs, et des compositions pharmaceutiques comprenant de tels composés. Lesdits composés sont utiles dans le traitement, la prévention ou l'atténuation des symptômes de maladies ou de troubles tels que le cancer ou les infections.The invention relates to compounds of formula (i '), methods of using such compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. Said compounds are useful in the treatment, prevention or alleviation of symptoms of diseases or disorders such as cancer or infections.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562270931P | 2015-12-22 | 2015-12-22 | |
US201662385341P | 2016-09-09 | 2016-09-09 | |
PCT/US2016/067925 WO2017112730A1 (en) | 2015-12-22 | 2016-12-21 | Heterocyclic compounds as immunomodulators |
Publications (2)
Publication Number | Publication Date |
---|---|
MA44144A MA44144A (en) | 2018-10-31 |
MA44144B1 true MA44144B1 (en) | 2021-03-31 |
Family
ID=75265335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA44144A MA44144B1 (en) | 2015-12-22 | 2016-12-21 | Heterocyclic compounds used as immunomodulators |
Country Status (1)
Country | Link |
---|---|
MA (1) | MA44144B1 (en) |
-
2016
- 2016-12-21 MA MA44144A patent/MA44144B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA44144A (en) | 2018-10-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA47043A1 (en) | Indole carboxamide compounds useful as kinase inhibitors | |
MA39783A (en) | USEFUL QUINOXALINE DERIVATIVES AS FGFR KINASE MODULATORS | |
MA40290A1 (en) | Immune-regulating agents | |
EA201992878A1 (en) | COMPOUNDS FOR TREATMENT OF HUNTINGTON'S DISEASE | |
MA40955B1 (en) | 2-amino-6- (difluoromethyl) -5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as bace1 inhibitors | |
MA38483A1 (en) | Inhibitors of ido | |
MA40111B1 (en) | Derivatives of tetrahydronaphthalene inhibiting mcl-1 protein | |
MA45020A (en) | AROMATIC SULPHONAMIDE DERIVATIVES | |
MA40123A1 (en) | Pyrimidines used as factor xia inhibitors | |
MA41562A1 (en) | 4-hydroxy-3- (heteroaryl) pyridine-2-one agonists for use in the treatment of cardiovascular disorders | |
MA37762B1 (en) | N-aryltriazole compounds used as antagonists of lpar | |
MA37764A1 (en) | N-alkyltriazole compounds used as antagonists of lpar | |
MA41179A (en) | PARG INHIBITOR COMPOUNDS | |
MA38810A1 (en) | Inhibitors of rorc2 related methods of use | |
MA37765A1 (en) | Substituted pyrazole compounds used as lpar antagonists | |
MA46229B1 (en) | Heteroaryl carboxamide compounds as inhibitors of ripk2 | |
MA38425B1 (en) | Bicyclic compounds for use as selective agonists for the s1p1 receptor | |
MA39447A1 (en) | (s) -pirlindole or its pharmaceutically acceptable salts for use in medicine | |
MA39253A1 (en) | Substituted bicyclic heteroaryl compounds used as rxr agonists | |
MA44144A (en) | HETEROCYCLIC COMPOUNDS USED AS IMMUNOMODULATORS | |
MA45392B1 (en) | Heterocyclic compounds used as immunomodulators | |
MA43263B1 (en) | Heterocyclic compounds used as immunomodulators | |
MA39533A1 (en) | Compounds, pharmaceutical composition and their use in the treatment of neurodegenerative diseases | |
MA52220B1 (en) | Heterocyclic compounds used as immunomodulators | |
MA52565B1 (en) | Tetrahydro-imidazo[4,5-c]pyridine derivatives as pd-11 immunomodulators |