MA38279A1 - Therapeutically active pyrazolo-pyrimidine derivatives - Google Patents

Therapeutically active pyrazolo-pyrimidine derivatives

Info

Publication number
MA38279A1
MA38279A1 MA38279A MA38279A MA38279A1 MA 38279 A1 MA38279 A1 MA 38279A1 MA 38279 A MA38279 A MA 38279A MA 38279 A MA38279 A MA 38279A MA 38279 A1 MA38279 A1 MA 38279A1
Authority
MA
Morocco
Prior art keywords
pyrimidine derivatives
therapeutically active
pyrazolo
active pyrazolo
spirocyclic
Prior art date
Application number
MA38279A
Other languages
French (fr)
Other versions
MA38279B1 (en
Inventor
Daniel James Ford
Richard Jeremy Franklin
Anant Ramrao Ghawalkar
Helen Tracey Horsley
Qiuya Huang
James Thomas Reuberson
Bart Vanderhoydonck
Original Assignee
Ucb Biopharma Sprl
Katholieke Universiteit Leuven K U Leuven R&D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Biopharma Sprl, Katholieke Universiteit Leuven K U Leuven R&D filed Critical Ucb Biopharma Sprl
Priority claimed from PCT/EP2013/077846 external-priority patent/WO2014096423A1/en
Publication of MA38279A1 publication Critical patent/MA38279A1/en
Publication of MA38279B1 publication Critical patent/MA38279B1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Cette invention concerne une série de dérivés de pyrazolo[3,4-d]pyrimidine qui sont substitués à la position 4 par un fragment monocyclique, bicyclique ponté ou spirocyclique de type diaza, qui sont bénéfiques pour traiter et/ou prévenir diverses maladies humaines, comprenant les troubles inflammatoires, autoimmuns et oncologiques ; les maladies virales et le paludisme ; et le rejet de greffes d'organes et de cellules.This invention relates to a series of pyrazolo [3,4-d] pyrimidine derivatives which are substituted at the 4-position by a monocyclic, bridged bicyclic or spirocyclic diaza moiety, which are beneficial for treating and / or preventing various human diseases, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and rejection of organ and cell transplants.

MA38279A 2012-12-20 2013-12-20 Therapeutically active pyrazolo-pyrimidine derivatives MA38279B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1223021.5A GB201223021D0 (en) 2012-12-20 2012-12-20 Therapeutic agents
PCT/EP2013/077846 WO2014096423A1 (en) 2012-12-20 2013-12-20 Therapeutically active pyrazolo-pyrimidine derivatives

Publications (2)

Publication Number Publication Date
MA38279A1 true MA38279A1 (en) 2018-02-28
MA38279B1 MA38279B1 (en) 2018-10-31

Family

ID=47682284

Family Applications (1)

Application Number Title Priority Date Filing Date
MA38279A MA38279B1 (en) 2012-12-20 2013-12-20 Therapeutically active pyrazolo-pyrimidine derivatives

Country Status (4)

Country Link
EC (1) ECSP15031293A (en)
GB (1) GB201223021D0 (en)
GT (1) GT201500169A (en)
MA (1) MA38279B1 (en)

Also Published As

Publication number Publication date
GT201500169A (en) 2019-08-30
GB201223021D0 (en) 2013-02-06
MA38279B1 (en) 2018-10-31
ECSP15031293A (en) 2018-07-31

Similar Documents

Publication Publication Date Title
EA201500654A1 (en) THERAPEUTICALLY ACTIVE DERIVATIVES OF PYRAZOLOPYRIMIDINE
CY1121512T1 (en) METHODS AND INTERMEDIATIONS FOR THE PREPARATION OF JAK SUSPENDER
MA40770B1 (en) FUSED PENTACYCLIC IMIDAZOLE DERIVATIVES
EA201990048A1 (en) [1,2,4] TRIAZOLO [1,5-a] PYRIDINYL-SUBSTITUTED INDOL COMPOUNDS
EA201171454A1 (en) N- (GETERO) ARYLPYRROLIDINE DERIVATIVES PYRAZOL-4-ILPYRROLO [2,3-d] PYRIMIDINES AND PYRROL-3-ILPYRROLO [2,3-d] PYRIMIDINES AS AN INITIATORS YANUS-I-I-I-I-I-I-I-I-I-I-I-IU-ZY-3-d)
EA201990657A1 (en) COMPOUNDS AND COMPOSITIONS AS ENDOSOMAL TOLL-LIKE RECEPTOR INHIBITORS
EA201301353A1 (en) COMPOSITIONS AND METHODS OF OBTAINING PYRIMIDINE AND PYRIDINE COMPOUNDS WITH VTK INHIBITING ACTIVITY
BR112015009942A2 (en) tricyclic fused thiophene derivatives as jak inhibitors
MA38183A1 (en) Pyrrolopyrimidine compounds as kinase inhibitors
EA201492176A1 (en) SELECTIVE PI3K DELTA INHIBITORS
EA201270480A1 (en) NEW CONNECTIONS
MA52856B1 (en) Heteroaryl or fused aryl bicyclic compounds and their use as irak4 inhibitors
BR112018006135A2 (en) fused pyrazole derivatives as kinase inhibitors
EA201590930A1 (en) DOSAGE FORMS OF RUXOLITINIB WITH Slow Release.
MX370814B (en) Substituted pyrazolo[3,4-d]pyrimidines and uses thereof.
NO20075560L (en) Purine and imidazopyridine derivatives for immunosuppression
EA201591689A1 (en) NEW N-ACYL- (3-substituted) - (8-substituted USE IN DISORDERS MEDIATED BY NK-3 RECEPTOR
EA201001518A1 (en) DERIVATIVES 1-HETEROCYCLIL-1,5-DIHYDROPYRAZOLO [3,4-D] Pyrimidine-4-SHE AND THEIR APPLICATION AS PDE9A MODULATORS
TW200631583A (en) Substituted pteridines for the treatment of inflammatory diseases
MA37946A1 (en) Treatment of rheumatoid arthritis
MA34844B1 (en) (1,2,4) TRIAZOLO [4,3-A] QUINOXALINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES
CA2903737C (en) Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor
IN2015DN03751A (en)
TR201901338T4 (en) Pyrazolo-Pyridine Derivatives as Kinase Inhibitors
EA202190323A1 (en) IMIDAZO [1,2-b] PYRIDAZINES AS TRK INHIBITORS