MA33351B1 - Formes stables du n-(2,6-diméthyl-4-morpholin-4-ylphényl)-3,3-diméthylbutyramide - Google Patents
Formes stables du n-(2,6-diméthyl-4-morpholin-4-ylphényl)-3,3-diméthylbutyramideInfo
- Publication number
- MA33351B1 MA33351B1 MA34435A MA34435A MA33351B1 MA 33351 B1 MA33351 B1 MA 33351B1 MA 34435 A MA34435 A MA 34435A MA 34435 A MA34435 A MA 34435A MA 33351 B1 MA33351 B1 MA 33351B1
- Authority
- MA
- Morocco
- Prior art keywords
- dimethyl
- morpholine
- phenyl
- stable form
- dimethylbutyramide
- Prior art date
Links
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- OVEJXWFUXCATFY-UHFFFAOYSA-N n-(2,6-dimethyl-4-morpholin-4-ylphenyl)-3,3-dimethylbutanamide Chemical compound CC1=C(NC(=O)CC(C)(C)C)C(C)=CC(N2CCOCC2)=C1 OVEJXWFUXCATFY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200900597 | 2009-05-11 | ||
| PCT/DK2010/050101 WO2010130260A2 (en) | 2009-05-11 | 2010-05-11 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33351B1 true MA33351B1 (fr) | 2012-06-01 |
Family
ID=42237259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34435A MA33351B1 (fr) | 2009-05-11 | 2010-05-11 | Formes stables du n-(2,6-diméthyl-4-morpholin-4-ylphényl)-3,3-diméthylbutyramide |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP2430008A2 (de) |
| JP (1) | JP2012526152A (de) |
| KR (1) | KR20120022934A (de) |
| CN (1) | CN102459208A (de) |
| AR (1) | AR076556A1 (de) |
| AU (1) | AU2010246724B2 (de) |
| BR (1) | BRPI1013930A2 (de) |
| CA (1) | CA2761383A1 (de) |
| CL (1) | CL2011002814A1 (de) |
| CO (1) | CO6460741A2 (de) |
| CR (1) | CR20110590A (de) |
| DO (1) | DOP2011000351A (de) |
| EA (1) | EA201171381A1 (de) |
| GE (1) | GEP20146006B (de) |
| IL (1) | IL216148A0 (de) |
| MA (1) | MA33351B1 (de) |
| MX (1) | MX2011011885A (de) |
| NZ (1) | NZ596738A (de) |
| SG (1) | SG175968A1 (de) |
| TN (1) | TN2011000557A1 (de) |
| TW (1) | TW201041857A (de) |
| WO (1) | WO2010130260A2 (de) |
| ZA (1) | ZA201108112B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119490430A (zh) | 2019-08-02 | 2025-02-21 | H.隆德贝克有限公司 | 用于在癫痫或癫痫发作中使用的作为Kv7钾通道开放剂的醇衍生物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI349666B (en) * | 2004-03-12 | 2011-10-01 | Lundbeck & Co As H | Substituted morpholine and thiomorpholine derivatives |
| BRPI0716715B1 (pt) * | 2006-08-23 | 2021-07-06 | Xenon Pharmaceuticals, Inc | Derivados de 4-(n-azacicloalquil) anilidas como moduladores de canal de potássio, seus usos, produto, composição, comprimido e cápsula |
| EP2185149A1 (de) * | 2007-08-01 | 2010-05-19 | H. Lundbeck A/S | Verwendung von kncq-kaliumkanal-öffnern zur verringerung von symptomen oder zur behandlung von erkrankungen oder störungen mit unterbrechung des dopaminergen systems |
-
2010
- 2010-05-06 TW TW099114459A patent/TW201041857A/zh unknown
- 2010-05-10 AR ARP100101588A patent/AR076556A1/es unknown
- 2010-05-11 KR KR1020117026958A patent/KR20120022934A/ko not_active Withdrawn
- 2010-05-11 JP JP2012510116A patent/JP2012526152A/ja active Pending
- 2010-05-11 MX MX2011011885A patent/MX2011011885A/es not_active Application Discontinuation
- 2010-05-11 BR BRPI1013930A patent/BRPI1013930A2/pt not_active IP Right Cessation
- 2010-05-11 WO PCT/DK2010/050101 patent/WO2010130260A2/en not_active Ceased
- 2010-05-11 CA CA2761383A patent/CA2761383A1/en not_active Abandoned
- 2010-05-11 SG SG2011082492A patent/SG175968A1/en unknown
- 2010-05-11 GE GEAP201012498A patent/GEP20146006B/en unknown
- 2010-05-11 CN CN2010800321765A patent/CN102459208A/zh active Pending
- 2010-05-11 AU AU2010246724A patent/AU2010246724B2/en not_active Ceased
- 2010-05-11 EA EA201171381A patent/EA201171381A1/ru unknown
- 2010-05-11 EP EP10719726A patent/EP2430008A2/de not_active Withdrawn
- 2010-05-11 NZ NZ596738A patent/NZ596738A/xx not_active IP Right Cessation
- 2010-05-11 MA MA34435A patent/MA33351B1/fr unknown
-
2011
- 2011-11-03 IL IL216148A patent/IL216148A0/en unknown
- 2011-11-04 TN TNP2011000557A patent/TN2011000557A1/en unknown
- 2011-11-04 ZA ZA2011/08112A patent/ZA201108112B/en unknown
- 2011-11-10 CL CL2011002814A patent/CL2011002814A1/es unknown
- 2011-11-11 CR CR20110590A patent/CR20110590A/es unknown
- 2011-11-11 DO DO2011000351A patent/DOP2011000351A/es unknown
- 2011-11-11 CO CO11153611A patent/CO6460741A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SG175968A1 (en) | 2011-12-29 |
| IL216148A0 (en) | 2012-01-31 |
| TW201041857A (en) | 2010-12-01 |
| BRPI1013930A2 (pt) | 2019-09-24 |
| CA2761383A1 (en) | 2010-11-18 |
| NZ596738A (en) | 2013-04-26 |
| CN102459208A (zh) | 2012-05-16 |
| EP2430008A2 (de) | 2012-03-21 |
| WO2010130260A2 (en) | 2010-11-18 |
| JP2012526152A (ja) | 2012-10-25 |
| MX2011011885A (es) | 2011-12-06 |
| TN2011000557A1 (en) | 2013-05-24 |
| CO6460741A2 (es) | 2012-06-15 |
| AR076556A1 (es) | 2011-06-22 |
| KR20120022934A (ko) | 2012-03-12 |
| CL2011002814A1 (es) | 2012-04-13 |
| WO2010130260A3 (en) | 2011-06-16 |
| GEP20146006B (en) | 2014-01-10 |
| AU2010246724A1 (en) | 2011-12-08 |
| EA201171381A1 (ru) | 2012-05-30 |
| CR20110590A (es) | 2012-02-22 |
| WO2010130260A9 (en) | 2012-10-18 |
| ZA201108112B (en) | 2013-01-30 |
| DOP2011000351A (es) | 2012-01-31 |
| AU2010246724B2 (en) | 2013-03-21 |
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