MA32174B1 - Solid orodispersible preparation - Google Patents

Solid orodispersible preparation

Info

Publication number
MA32174B1
MA32174B1 MA33210A MA33210A MA32174B1 MA 32174 B1 MA32174 B1 MA 32174B1 MA 33210 A MA33210 A MA 33210A MA 33210 A MA33210 A MA 33210A MA 32174 B1 MA32174 B1 MA 32174B1
Authority
MA
Morocco
Prior art keywords
fine granules
solid
orodispersible
preparation
pharmaceutically acceptable
Prior art date
Application number
MA33210A
Other languages
Arabic (ar)
French (fr)
Inventor
Takashi Kurasawa
Yasuko Watanabe
Yoshihiro Omachi
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40791576&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32174(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of MA32174B1 publication Critical patent/MA32174B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne une préparation solide orodispersible de type comprimé obtenu par compression de fines granules à capacité de libération contrôlée d'un principe actif acceptable sur le plan pharmaceutique et d'un additif, et analogues; ladite préparation solide orodispersible contenant de fines granules enrobées d'une couche d'enrobage qui contient un polymère permettant d'obtenir une coulée de film présentant un allongement à la rupture compris entre environ 100 et environ 700 %. Au moyen de ladite préparation, la rupture des fines granules pendant la compression peut être éliminée lors de la production d'une préparation solide orodispersible contenant de fines granules à capacité de libération contrôlée d'un principe actif acceptable sur le plan pharmaceutique.The present invention relates to a tablet-type orodispersible solid preparation obtained by compressing fine granules with controlled release capacity of a pharmaceutically acceptable active ingredient and an additive, and the like; said solid orodispersible solid preparation containing fine granules coated with a coating layer which contains a polymer for obtaining a film cast having an elongation at break of from about 100 to about 700%. By means of said preparation, the breaking of the fine granules during compression can be eliminated during the production of a solid orodispersible solid preparation containing fine granules with controlled release capacity of a pharmaceutically acceptable active ingredient.

MA33210A 2008-03-11 2010-09-29 Solid orodispersible preparation MA32174B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008061673 2008-03-11
JP2008334920 2008-12-26
PCT/JP2009/054983 WO2009113703A2 (en) 2008-03-11 2009-03-10 Orally-disintegrating solid preparation

Publications (1)

Publication Number Publication Date
MA32174B1 true MA32174B1 (en) 2011-03-01

Family

ID=40791576

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33210A MA32174B1 (en) 2008-03-11 2010-09-29 Solid orodispersible preparation

Country Status (26)

Country Link
US (2) US9241910B2 (en)
EP (1) EP2254556A2 (en)
JP (1) JP5604304B2 (en)
KR (1) KR20100129761A (en)
CN (2) CN104127368A (en)
AR (1) AR070863A1 (en)
AU (1) AU2009224254A1 (en)
BR (1) BRPI0909439A2 (en)
CA (1) CA2717947C (en)
CL (1) CL2009000557A1 (en)
CO (1) CO6321224A2 (en)
CR (1) CR11709A (en)
DO (1) DOP2010000273A (en)
EA (1) EA021792B1 (en)
EC (1) ECSP10010538A (en)
GE (1) GEP20135845B (en)
IL (1) IL207989A0 (en)
MA (1) MA32174B1 (en)
MX (1) MX2010009824A (en)
MY (1) MY173730A (en)
NZ (1) NZ588407A (en)
PE (2) PE20141034A1 (en)
TW (1) TWI441658B (en)
UY (1) UY31698A (en)
WO (1) WO2009113703A2 (en)
ZA (1) ZA201006679B (en)

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CN112121067A (en) * 2020-11-16 2020-12-25 深圳科兴药业有限公司 Bifidobacterium infantis microcapsule and preparation method thereof
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Also Published As

Publication number Publication date
PE20091620A1 (en) 2009-11-12
JP2011513204A (en) 2011-04-28
TW200944249A (en) 2009-11-01
US20150037423A1 (en) 2015-02-05
ECSP10010538A (en) 2010-11-30
CR11709A (en) 2010-11-04
EA201071054A1 (en) 2011-04-29
EA021792B1 (en) 2015-09-30
AR070863A1 (en) 2010-05-12
CL2009000557A1 (en) 2010-10-01
DOP2010000273A (en) 2010-09-30
IL207989A0 (en) 2010-12-30
AU2009224254A2 (en) 2010-11-18
CA2717947A1 (en) 2009-09-17
TWI441658B (en) 2014-06-21
UY31698A (en) 2009-11-10
CN104127368A (en) 2014-11-05
US20110091563A1 (en) 2011-04-21
WO2009113703A3 (en) 2010-06-17
EP2254556A2 (en) 2010-12-01
CN102026627A (en) 2011-04-20
KR20100129761A (en) 2010-12-09
BRPI0909439A2 (en) 2015-12-15
ZA201006679B (en) 2011-11-30
CA2717947C (en) 2020-07-07
CN102026627B (en) 2016-10-26
JP5604304B2 (en) 2014-10-08
CO6321224A2 (en) 2011-09-20
NZ588407A (en) 2012-07-27
PE20141034A1 (en) 2014-09-10
AU2009224254A1 (en) 2009-09-17
MY173730A (en) 2020-02-18
MX2010009824A (en) 2010-09-28
WO2009113703A2 (en) 2009-09-17
US9241910B2 (en) 2016-01-26
GEP20135845B (en) 2013-06-10

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