LV15576A - Fluorescējošie akridīnija sāļi, to sintēze un izmantošana kardiolipīna noteikšanai - Google Patents

Fluorescējošie akridīnija sāļi, to sintēze un izmantošana kardiolipīna noteikšanai

Info

Publication number
LV15576A
LV15576A LVP-19-64A LV190064A LV15576A LV 15576 A LV15576 A LV 15576A LV 190064 A LV190064 A LV 190064A LV 15576 A LV15576 A LV 15576A
Authority
LV
Latvia
Prior art keywords
cardiolipin
detection
synthesis
acridinium salts
fluorescent acridinium
Prior art date
Application number
LVP-19-64A
Other languages
English (en)
Inventor
Pāvels ARSENJANS
Pāvels DIMITRIJEVS
Original Assignee
Latvijas Organiskās Sintēzes Institūts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Latvijas Organiskās Sintēzes Institūts filed Critical Latvijas Organiskās Sintēzes Institūts
Priority to LVP-19-64A priority Critical patent/LV15576A/lv
Priority to PCT/IB2020/058457 priority patent/WO2021105780A1/en
Priority to CN202080082665.5A priority patent/CN114787287B/zh
Priority to US17/777,506 priority patent/US20230013542A1/en
Priority to EP20776234.5A priority patent/EP4065643B1/en
Publication of LV15576A publication Critical patent/LV15576A/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B15/00—Acridine dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass
    • C09B69/008—Dyes containing a substituent, which contains a silicium atom
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Izgudrojums attiecas uz jauniem aizvietotiem akridīnija sāļiem kā fluorescējošām krāsvielām, kā arī uz to ražošanas metodēm un atklāto savienojumu izmantošanu kardiolipīna noteikšanai.
LVP-19-64A 2019-11-28 2019-11-28 Fluorescējošie akridīnija sāļi, to sintēze un izmantošana kardiolipīna noteikšanai LV15576A (lv)

Priority Applications (5)

Application Number Priority Date Filing Date Title
LVP-19-64A LV15576A (lv) 2019-11-28 2019-11-28 Fluorescējošie akridīnija sāļi, to sintēze un izmantošana kardiolipīna noteikšanai
PCT/IB2020/058457 WO2021105780A1 (en) 2019-11-28 2020-09-11 Fluorescent acridinium salts, synthesis thereof and use for detection of cardiolipin
CN202080082665.5A CN114787287B (zh) 2019-11-28 2020-09-11 荧光吖啶盐、其合成和用于检测心磷脂的应用
US17/777,506 US20230013542A1 (en) 2019-11-28 2020-09-11 Fluorescent acridinium salts, synthesis thereof and use for detection of cardiolipin
EP20776234.5A EP4065643B1 (en) 2019-11-28 2020-09-11 Fluorescent acridinium salts, synthesis thereof and use for detection of cardiolipin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LVP-19-64A LV15576A (lv) 2019-11-28 2019-11-28 Fluorescējošie akridīnija sāļi, to sintēze un izmantošana kardiolipīna noteikšanai

Publications (1)

Publication Number Publication Date
LV15576A true LV15576A (lv) 2021-06-20

Family

ID=69063840

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-19-64A LV15576A (lv) 2019-11-28 2019-11-28 Fluorescējošie akridīnija sāļi, to sintēze un izmantošana kardiolipīna noteikšanai

Country Status (5)

Country Link
US (1) US20230013542A1 (lv)
EP (1) EP4065643B1 (lv)
CN (1) CN114787287B (lv)
LV (1) LV15576A (lv)
WO (1) WO2021105780A1 (lv)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193983A (en) * 1978-05-16 1980-03-18 Syva Company Labeled liposome particle compositions and immunoassays therewith
GB201122099D0 (en) * 2011-12-22 2012-02-01 Almac Sciences Scotland Ltd Dyes
JP6606096B2 (ja) * 2014-04-01 2019-11-13 ハワード ヒューズ メディカル インスティテュート アゼチジン−置換蛍光化合物
CN107807238A (zh) * 2016-06-30 2018-03-16 深圳市亚辉龙生物科技股份有限公司 抗心磷脂抗体化学发光免疫检测试剂盒及其制备方法
CN107090190B (zh) * 2017-04-24 2019-09-06 北京科技大学 一类吖啶盐染料及其制备方法和应用

Also Published As

Publication number Publication date
WO2021105780A1 (en) 2021-06-03
EP4065643A1 (en) 2022-10-05
EP4065643C0 (en) 2023-12-13
CN114787287A (zh) 2022-07-22
CN114787287B (zh) 2024-05-07
EP4065643B1 (en) 2023-12-13
US20230013542A1 (en) 2023-01-19

Similar Documents

Publication Publication Date Title
CO6852084A2 (es) Nuevos compuestos sustituidos con halógeno
EA201692193A1 (ru) Способы получения ингибитора jak1 и его новых форм
TR201905217T4 (tr) Kopanlisib ve bunun dihidroklorid tuzunun sentezi.
EA032920B1 (ru) Способы получения соединений бензохинолина
MX2015017156A (es) Inhibidores de bace.
MA39152A1 (fr) Cyclopentanes substitués en 1,2 utilisés comme antagonistes du récepteur d'orexine
MY189986A (en) (per)fluoropolyether polymers
TR201904346T4 (tr) Copanlisib ve bunun dihidroklorür tuzunun sentezi.
MX2022002831A (es) Compuestos heterociclicos.
MX2019013979A (es) Metodos para la preparacion de compuestos heterociclicos de 1,3-benzodioxol.
MY190814A (en) (per)fluoropolyether polymers
PH12020550905A1 (en) Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives
EA201991241A1 (ru) Способ получения метоксиметилпиридин дикарбоксилата
MX2021003070A (es) Un proceso de fabricación de compuestos heterocíclicos de 2-nitroimino.
MX369556B (es) Procesos para la preparacion de derivados acidos de n-acetilgalactosamina (galnac).
ZA202202245B (en) Quinoline derivatives as protein kinase inhibitors
PH12017501404A1 (en) Diaza-benzofluoranthrene compounds
MA39387A1 (fr) Colorants réactifs fluorescents, procédé de production et utilisation de ceux-ci
MX2019009242A (es) Un proceso novedoso para la sintesis de 1-aril-1-trifluoro-metil-c iclopropanos.
CR20110208A (es) Proceso para la preparación de benzonorbornenos
LV15576A (lv) Fluorescējošie akridīnija sāļi, to sintēze un izmantošana kardiolipīna noteikšanai
MX2022002017A (es) Metodo para producir derivado de heterociclideno acetamida.
RS54689B1 (en) CONNECTED BICYCLIC 2,4- DIAMINOPYRIMIDINE DERIVATIVE AS DUAL ALK AND FAK INHIBITOR
EA201391793A1 (ru) Новый способ синтеза 7-хлор-4-(пиперазин-1-ил)-хинолина
EA202092707A1 (ru) Огнеупор, шихта для его получения, способ его получения, а также применение такого огнеупора