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Application filed by Latvijas Medicinas Akademija, Bikova Jevgenija, Kangizers AleksandrsfiledCriticalLatvijas Medicinas Akademija
Priority to LVP-98-234ApriorityCriticalpatent/LV12487B/en
Publication of LV12487ApublicationCriticalpatent/LV12487A/en
Publication of LV12487BpublicationCriticalpatent/LV12487B/en
Investigating Or Analysing Biological Materials
(AREA)
Abstract
Invention relates to the field of medicine and particularly obstetrics. It concerns methods for diagnosing missed abortion. A method provides testing blood samples of pregnant woman. Two test-tubes are filled with leukocyte suspension in concentration 1 million cells per 1 ml and native serum of the woman in test. A combined preparation (rimolan) containing chorionic gonadotropin, progesterone, prolactin, estradiol and luteinizing hormone is added to the first test-tube for determination of a level of sensibilization of leukocytes. A presence of anti-sensibilizing antibodies against rimolan is determined in the second test-tube. A difference P between sensibilization index S and antibodies index Ba is calculated. Where S is equal or less than 30 and P is -10 or lesser ( -15, -20 etc.) the missed abortion is diagnosed. The method provides counting non-adhering cells in both test-tubes in presence of antigen - rimolan. This method allows to diagnose missed abortion in early stage of pregnancy - between the third and the sixth week.
LVP-98-234A1998-10-261998-10-26Method of diagnosis of missed abortion
LV12487B
(en)