LV10537B - Method for detecting of activity of stone formation process and of content of salts formating these stones in urolithiasis cases - Google Patents

Abstract

A method for determining the rock formation activity and the composition of rock-forming salts urolithiasis is characterized by the addition of a 9: 1.7: 1 protein solution of protein to the urine sample and 5: 1, the resulting mixture is applied as a drip on a smooth surface and dried for 24 hours, then the crystallization of salts is determined character in the edge of the sample: in the case of individual crystals, the complete crystallization of the conglomerate area in the case of a weak, medium or pronounced rock formation activity; determines the composition of these crystalline formations and at the same time determines the composition of the salts in the central zone of the sample, and then concludes by comparative analysis composition of stones forming stones

Description

LV 10537

CnocoE OriPEHEJIEHHH CTEITHH AKTHBHOCTH KAMHE0EPA30BAHHH H COCTABA KAMHEOBPA3YOMHX COJIEf MOUH ΠΡΗ yPOJ! HTHA3E

HacTOHmee Η3θ6ρβτΘΗΗβ othochtch k meton aHajiH3a b-06 jiacTH MeflHUHHbi, a TOUHee κ cnoco6y onpenejieHHH CTeneHH aKTHBHOCTH KaMHeo6pa30BaHHH h cocTaBa KaMHeo6pa3yiomHx cojieft mo-HH ΠρΗ ypOJIHTHa3e H MOJK6T HAUTH ΠρΗΜ6Η6ΙΙΗ6 B KJIHHHHeCKHX H HayuHbix HCCJienoBaHHHX ujih aHanH3a οτβπβΗΗ aKTHBHOCTH Kamhi-o6pa30BaHHfl; jijih HCCJiejbOBaHHH b ηηηβμηκθ npouecca KaMHeofipa-30BanHH; flJH is the mainHHH cojieBoro cocTaBa KaMHH Ha paHHHX CTa-uhhx ypojiHTa3a c uejibio npeaoTBpameHHH o6pa30BaHHH μοηθβογο KaMHH h onpeflejieHHH HHUHBHayajibHOH TepanHH npH ypojiHTHa3e. B HacToamee BpeMH npofijieMbi uHHaMHHecKoro HccjienoBaHHH npouecca KaMHeo6pa30BaHHH BcpraHH3Me vejioBeKa, ero HHTeHCHB-hocth, onpeaejieHHH cojieBoro cocTaea b npouecce KaMHeo6pa30Ba-hhh hbjthiotch aKTyajibHbiMH, Tax Kax no3BOJiawT npeuoTBpaTHTb 06-pa30BaHHe ΜΟΗΘΒΟΓΟ KaMHH, CBOeBpeMeHHO BHeCTH KOppeKTHPOBKy b yKa3aHHbifi npouecc, onpeuejiHTb h npoBOUHTb HHjtHBHnyajibHyio τβ ~ panHio npn ypojiHTHa3e.

H3BeCTHbI cnocoebl ΠρθΓΗ03ΗρθΒ3ΗΜΗ ypOJTHTHa3a, OCHOBaH-Hbie Ha BbiHBJieHHH npouecca KaMiieo6pa30BaHHH, e.g. cnoco6 nporH03HpoBaHHH nyTeM o6Hapy > KeHHH KpHCTajiJiOB cojiefi b CBeateBM-nymeHHOft Mone hjih nepe3 κοροτκοβ BpeMH nocjie MoneHcnycKaHHH (BEIlpenTeHeHCKHfi, " PyKOBOflCTBO of KJIHHHHeCKHM JiaSopaTOpHbJM I · HCCJiejjOBaHHHM ", 1964 , MenHUHHa, c.420-446) hjih cnoco6 nporao-3HpoBaHHH ypojiHTHa3a (SU, A, 1629846) ocHOBaHHbiii Ha onpene-JieHHH KpHCTajIJIOO6pa3yi0IUefi aKTHBHOCTH MOHH nyTeM CMemHBaHHH pacTBopoB cojieft xjiopHjua KajībUHH h oKcajiaTa ηβτρηη h momh, SKC-n03HUHH CMeCH h nOHCHeTa 06pa30BaBUIHXCH KpHCTaJIJIOB. 2

Onnako, yKa3amtt >! C cnoco6M iinnpnnjinnw TOJtbKo na BbmBjie-ηηθ npouecca KaMHeo6pa30BanHH η ηθ πο3βοληιοτ cyuHTb o CTene-hh aKTHBHOCTH θτογο npouecca. Η3ΒβοτβΗ cnoco6 nporH03HpoBanHH ypojiHTHa3a, πρκ κοτοροΜ npeujioHceHO onpejaejiHTb cTeneub pHCKa KpiīCTajiJiH3auHH < L > oc4 > ATA KajībUHH b moue nyTeM noucneTa c < | > opMHpoBaBinHXCH KpHCTajnioB on-peaejieHHoro pa3Mepa of MaTeMaTHuecKHM pacueīaM (" Urological Research, N 2, 15, 1987 , Springer-Verlag, H.-Tiselius, " Mea surement of the Risk of Calcium Phosphate Crystallization in Urine ", pp. 79-81). yKa3aHHbif cnoco6 ycjio * HeH MaTeMaTHuecKHMH pacMeTaMH h TaKJKe nanpaBJieH kuibko Ha βμηβπθηηθ npouecca Kan-Heodpa30BaiiHH. . ........ Η3βθοτθη tack "e cnoco6 nporH03HpoBaHHH ypojiHTua3a (PCT / 5U 91/00140) b b κοτοροΜ npo6y momh flo6aBJiHK) T solution was 6ejiKa, Ha-EXAMPLE ajib6yMHHa, mixture of BbicyuiHBaioT h npn HajiHUHH cnjioraHoii KpHCTajinH3auHH npo6bt, nporno3Hpy »T yponnTHa3. yKa3anHbift cno-co6 HanpaBJieH eggbock Ha βμηβηθηηθ npouecca KaMHeo6pa30BaHHH η Ηβ μοκθτ 6biTb Hcnojib30BaH henHeeHyHH CTenenH aKTHBHOc-th KaMHeo6pa30BaHHH.

KpOMe τογο, H3BecTHbi cnoco6bi onpeuejieHHH cocTaea cojiefi NPU ypojtHTHa3e (BEFlpeuTeMeHCKHfi, " PyKOBOucTBO of KJiHHHuec-khm jia6opaTopHbiM HccjieuoBaHHHM 1964 MeuHUHHa, MocKea, c. 452-454; Wandt M., Underhill LJUrol ", 1988, 61, N 6, 478-481, G. Schubert, G. G. Brien, Adam K. " Z.Klin. Med ", 1989, 44, N 11, 923-928; Nichino T., Sakura T., Sato T., Koiso K., Ka-nk S., " Jap. J.Nephrol ", 1987, 29, N 5, 571-575). BCE 3th cnoco6bi ocHOBaHbi Ha HccjieuoBaiiHH κομποηθητοβ Mon "(cojieBoro ocajaica, neck, κοηκρθμθητοβ) φΗ3Ηκο-xHMHMecKHM nyTeM c HC- - 3 - EN 10537 nOJTb30BaHHeM anCOp6UHH, ΗΟΗΗΟΓΟ ΟδΜβΗβ, e.g. XpOMaTOrpa-φΗΗ C nOMOmfeīO ρβΗΤΓΘΗΟΟΤργΧΤγρΗΟΓΟ aHajIH3a, ρβΗΤΓΘΗΟΟΠΘΧΤ-pajībHOro aHajiH3a, TepMoaHajiH3a c noMonjbio HflepHo-MarHHTHoro pe30HaHca, sjieKTpoHHo-poleMarHHTHoro pe30HaHca hjih ηργίΉχ ΟΠΗΗ-3φφθΚΤΟΒ. YKa3aHHbie MeTOflbI ΠρΗΓΟΑΗΜ TOJIbKO HJIH HCCJieflOBaHHJI οφορ-ΜΗρΟΒΒΒΠΙΗΧΟΗ KaMHefi, Bblfl6 JieHHbIX H3 OpraHH3Ma, Η He n03BOJIHK) T onpeflejiHTb xHMHqecKyw npnpofly KaMHeo6pa30BaHHH Ha paHHHx CTA-Ληηχ ypojiHTHa3af a tack "e σφορΜΗροΒβΒίπΗχαΗ KaMHefS, ho He bm-flejieHHbIX H3 OpraHH3Ma.

CnocoS onpeae ^ eHHH xHMHtiecKoro cocTaBa KaMHeo6pa3yiomHX cojieft If paHHHX οτθαπηχ ypojiHTHa3a, a Taoie οφορΜΗροΒΒΒΠΗχσπ, ho ηθ BbiiieHeHHbix H3 opraHH3Ma KaMHeii, Ηβ Η3Βθοτθη. 3aHBJiHe-Mblfl cnocoe OnpefleJieHHH CTeneHH aKTHBHOCTH KaMHe06pa30BaHHH H cocTaBa KaMHeo6pa3yiomHX cojiee μο ^ ιη πρκ ypojiHTHa3e HBJiHeTCH HOBbiM h b JiHTepaType ηθ onH. B οοηοβυ Η3θδρβτβΗΗΗ nojio "EHA 3anaMa pa3pa6oTaTb TaKoft CII0C06, KOTOpblii n03B0JIHJI dbl 6bICTpO Η ΤΟΊΗΟ OnpeneJIHTb CTeneHb aKTHBHOCTH KaMHeoepasoBaHHH πρκ ypoHHTHa3e, a TAKÁCS onpejje-JlHTb COJieBOfl COCTaB KaMHH Ha JIM60M 3Tane ero φθρΜΗρθΒ3ΗΗΗ. 3a "AMA pemeHa τθμ, hto b cnoco6e onpeaejieHHH aKTHBHOCTH KaMHeo6pa30BaHHH h cocTaBa KaMHeo6pa3ywmHx cojieft μομη πρκ ΥρθΗΗΤΗ33β, COrJiaCHO Η3θ6ρβΤβΗΗΙ0, B προδγ MOHH BBOflHT BOflHblft solution was 6ejiKa b cooTHomeHHH 9: 1, 7: 1 hjih 5: 1 σοοτΒβτστΒβΗΗΟ, ΠΟΛγΜβΗΗγΗ) A mixture of B ΒΗΗβ KaīlJIH HaHOCHT Ha ρΟΒΗγίΟ ΠΟΒβρΧΗΟΟΤΒ h BbicyuiHBaioT b TeueHne He μθηθθ 24 ^ ACOBO, 3aTeM onpenejiHWT xapaKTep KpHCTajuiH3auHH cojieft b KpaeBOft 3θΗβ npodbt, πρκ Ha- I · JIHHHH eZlHHHMHbIX KpHCTajIJIOB, ΗΧ ΚΟΗΓ JIOMepaTOB HJIH riOJIHOft 4

KpHCTaJIJlH3aUHH 3Τ0β 30HbI CyflHT a respective O CJia6oft, YME ~ peHHOft HJIH Bbipa ^ eHHOH CTeneHH aKTHBHOCTH KaMHeo6p030BaHHH H BblHB jThis COCTaB 3ΤΗΧ KpHCTajIJIHHeCKHX 06pa30BaHHft C OflHOBpe-MeHHbiM onpejtejieHHeM cocTaBa cojieft ueHTpajībHOft 30iibi npo6bi h nocneByioiUHM προβθβθηηθμ cpaBHHTejibHoro aHajiH3a 3.thx cocTaBOB Bjih onpeaejieHHH KaMHeo6pa3yioiHHX cojieft mohh. D Ka ^ ecTne Bojmoro pacTBopa 6ejixa npejnnoHTHTejrbHO hc-nojib3ywT 8-12% BOflHbiH pacTBop anb6yMHHa. Kejiecoo6pa3HO zijih noBbimeHHH tohhocth aHaHiH3a BbicymHBaHHe HaHeceHHOft Ha poBHyro nOBepXHOCTb Kanjl nOJiyueHHOfl CMSCH ΓφΟΒΟΛΗΤΒ ΠρΗ KOMHaTHOfi TeMnepaType. C uenbio γοκορβΗΗΗ h nOBbimeHHH tohhocth aHajiH3a npenno ^ THTejibHO nnn βηηβλθηηη sjieMeHTOB cocTaBa-yKa3aHHbix KpHCTajuiHMecKHx 06pa30BaHHfl Hcnojib30BaTb peiiTreHOcneKTpajīb-Hblfi MHKpOaHajIH3. 3aBBJIBeMblfl cnocoe BblHBHJI 3aBHCHMyiO CBH3b aKTHBHOCTH KaM-

Heo6pa30BaimH c ηητθηοηβηοοτβιο KpHCTajiJiH3auHH cojiefl b Kpae-ΒΌύ 30Ηβ προβω μοηη. 3το πο3Βοληθτ 6bicTpo h tohho onpejiejiHTb B προδβ MOHH CTeneHb aKTHBHOCTH KaMHeo6pa30BaHHH, HTO flaeT B03M0WH0CTb npOBOflHTb HCCJieflOBaHHe npOUeCCa KaMHeo6pa30BaHHH B flHHaMHKe, CBOeBpeMeHHO BHOCHTb ΚΟρρβΚΤΗρΟΒΚγ B yKa3aHHblft npouecc, npeflOTBparaaH o6pa30BaHHe μοηθβογο κθμηη, a Τ3κκβ πρπ Heo6xoziHMOCTH ocyņecTBJiHTb HHHHBHiiyajibHyio TepanHio. KpoMe το-γο, 3aHBJIH6Mbl3 CnOCOfi Π03Β0ΛΗβΤ eme FLO φθρΜΗρθΒ3ΗΗΗ KaMHH B opraHH3Me onpejaejiHTb cocTaB KaMHeo6pa3yiomHx cojietf h npHHHTb uejieHanpaBJieHHbie Mepbi ajih ηχ βμβθ, πθηηη H3 opraiiH3Ma h npeny-NPE ^ aeHHH ποοτυπλθηηη βτηχ cojiefl c h πητβθβοΑ Boho προ, αγκ-T3MH ΠΗΤ3ΗΗΗ. 3aHBJJHeMbIH Cn0C06 aHaJIH3a Π03Β0ΒΗβΤ ΠρΗ HajlH-hhh y CojibHoro b MOHSBbix πγτπχ KaMHH 3a onpenejieHHbift nepHOfl - 5 - EN 10537

Ha6jnoneHHH y3HaTb H3 κβκκχ KaMHeo6pa3yjonwx cojiefl < J > opMnpyeTCH difference nOBepXHOCTHbIH CJIOft, HTO ΜΟ? ΚβΤ 6bITb ΗβΟβΧΟΠΗΜΗΜ, HanpH-Mep, npH JIHTOTpHiTCHH.

MccjteflOBaime cocTaBa KaMHeo6pa3yiomHx cojieft b πηη3μηκθ (b tom qHcjie c MOM6HTa Ha ^ Ajia KaMHeo6pa30BaHHH) aaeT bo3Mojk-ηοοτβ ycTaHOBHTb cocTaB h nocjienyiorayKi cTpyicTypy Bcero Kamhi, HTO ΗΜΘβΤ 3Η3Η6ΗΗ6 IīpH ΠρΟΒβΠβΗΗΗ pe * HMA ΛΗΤΟΤρΗΠΟΗΗ.

KpoMe τογο, 3aaBJixeMbift cnoco6 aHajiH3a πο3ΒοηΗβτ ocymecT-BJiHTb uejieHanpaBjieHHyio npo $ HjiaKTHKy peHHHBHpoBaHHH ypojiHTHa-3a. Cnocofi yno6eH, προοτ b ηοποληθηηη, ηθ Tpe6yeT cneuHanb-ηογο annapaTypHoro οφορΜϋβΗΗΗ.

3aaBBiieMbift cnoco6 onpeflejieHHH οτθπθηη 3κτηβηοοτη Kamhi-o6pa30BaHHH, Kax yKa3aHO Bbime, ocHOBaH Ha ββιηβηθηηοη 3aBHCH-MOH CBH3H ΟΤΘΠΘΗΗ KpHCTajIJlH3aUHH COJieft B KpaeBOfi 30ΗΘ ΠρΟβω MOHH C aKTHBHOCTbfO KāMH0O6ρ330Β3ΗΗΗ. 3aHB JIHeMblft ΟΠΟΟΟβ OCy-mecTBiineTCH cyanoalkylimM6? B npo6y mohh ββοπητ BOflHbiS pacTBop 6eiKa (b KanecTBe KOTopor πρθηποητητθη & ηο Hcnojib3ywT t 8-12% -Hbift BOjciHbiS pacTBop ajib6yMHHa) b οοοτηοπθηηη 9: 1, 7: 1 HJJH 5: 1 COOTBeTCTBeHHO. flJIH aHaBH3a Μ03ΚΘΤ6bITb HCn0JIb30BaHa npo6a MOMH, B3HT3H B OJ3HOM H3 yKa3aHHbIX ΟΟΟΤΗΟΙΠΘΗΗΛ C BOflHblM pacTBopOM 6ei. Πηη ΒοοτοΒβρΗοοτΗ aHajiHaa MoryT 6biTb «cnojib-30Banbi flBa hjih τρπ BapnaHTa yKa3aHHbix cooTHomeHHft. 3aTeM Kan-yw nonyMeHHOft CMecH ηθηοοητ Ha poBHyw noBepxHOCTb h BbicymH-BaioT b τθηθηηθ ηθ μθηθθ 24 HacoB πρκ KOMHaTHOfl TeMnepaType. riocjie BbicyniHBaHHH onpenejiaioT ηητθηοηβηοοτβι KpHCTajuiH3a-uhh cojreft mohh b KpaeBOft 3θΗβ npo6bi: ejdHHHHHbie KpHCTajiJibi yKa-3biBawT Ha cjia6yio 3Κτηβηοοτβ npouecca KaMHeo6pa30BaHHH; HajiH-ηηθ KOHrjiOMepaTOB KpHCTajiJiOB coejift yMepeHHyw aKTHBHoeTb; 6 nOJlHaH KpHCTaJlJIH3aUHH COJiefl 3TOft 30Hbl - Ha Bbipa? KeHHyiO aKTHB-HOCTb npouecca KaMHeo6pa30BaHHH. ΟτςγτστΒΗβ KpHCTajuioB b KpaeBoA 3θΗβ CBHfleTejibCTByeT o TOM, τίτο Κ3ΜΗΘθ6ρ330Β3ΗΗβ Ηβ ΠρΟΗΟΧΟΗΗΤ. 3aHBJIHeMblfi cnocod no3BOJiaeT οηηοβρθμθηηο ocymecTBJiHTb βμηβλθηηθ οτβπβΗΗ aKTHB-hocth η cocTaBa KaMHeo6pa3ywmHX cojieft μομη. Πρκ HajiHMHH κρκο-TajiJiHHecKHx odpa30BaHHH b icpaeBofi 30ηθ προβω c noMombio φΗ3Η-μθοκηχ ΜθΤοποΒ (πρΘππο ^ τΗτβΛΒHo peHTreHocneKTpaHbHoro ΜΗΚρΟ-aHajiH3a) onpeflejikioT sjieMeHTbift cocTaB sthx KpHCTajiJiHuecKHX 06- pa30BaHHfl. OxyHOBpeMeHHo onpenejiHioT cocTae cojiefi ueHypHoPH / 30HbI npoSbl ΜΟ «ΪΗ H npOBOflHT CpaBHHTeJIbHblft aHaJIH3 3ΤΗΧ COCTa-BOB, Ha OCHOBaHHH? KaMHeo6pa30BaHHe - sto flHHaMHMec-KHi npouecc, COJieBOft COCTaB ΚΟΤΟρΟΓΟ ΜΟ > ΚΘΤ Η3ΜβΗΗΤΒΟΗ BO Bpe-μθηη. 3aHBJiaeMbifl MeTon πο3βοηηθτ onpezieHHTb cojieBoft cocTaB KaMHH, KOTOpblft $ OpMHpyeTCH HJIH ΜΟ?

3aHBJiHeMbift fcnocod npomen ηοπμτηηηη b κηηηη ^ θοκηχ nadopa-τορΗπχ. Bjih onpeaejieHHH οτβπβΗΗ 3kthbhocth KaMHeo6pa30BaHH "o6cJieflOBaHO 12 6οπβημχ - KaMHeBbmejiHTejieft (the ecTb dojibHbie, y κοτορΜχ πθρηοπημθοκη HadJiioflaeTCH caMonpoH3bojibnoe pa3pyme-ΗΗβ H BbIB6fl0HH6 ΚβΜΗββ) H 128 npaKTHMeCKH 3flOpOBbIX jihua B FLO-KHHHHMecKOfl CTaflHH ypojiHTHa3a, uto dbuio ycTaHOBJieHO paHee H3-BSCTHblM M6TOHOM, HO ΗΘΗ3ΒΘ0ΤΗ3 ΟΤΘΠΘΗΒ aKTHBHOCTH KaMHeOdpa-sonaiiHn. MccncflonaiiHa coctobjih b cjienyiotneM: dpajiH npo6y momh, BBOflHJIH B Hee BOHHblfi solution of dejlKa (aHbdyMHHa) B COOTHOraeHHH 9: 1, 7: 1 hhh 5: 1 οοοτβθτοτβθηηο, nojiyMeHHyw mixture of b βηαθ Kan-Jih HaHOCHJIH Ha ΠΟΒβρΧΗΟΟΤΒ ΠρθΗΜΘΤΗΟΓΟ CTeKJia, BbICyfflHBajlH 7 ΠρΗ ΚΟΜΗ3ΤΗΟΗ ΤβΜΠβρΒΤγρβ Β ΤβΗΘΗΗΘ 24 ^ SCOB. 3βΤΘΜ ΠρΟΒΟΛΗ-JIH HCCJiejJOBaHHe HajTHMHH KpHCTajlJlOB Β KpaeBOfi 3 ΟΗβ Bb! CymHBa- ηηη προ6ω. Pe3yjibTaTbi HccjiaoBaHHH npeflCTaBJieHbi b Ta6jnnjax 1 Η 2.

Ta6jiHua 1 ι <

KjiHHHMecKHe h jiafiopaTopHbie naHHbie 6ojibHbix - KAMHEBblUEJIHTEHEfl

CooTHomeHHe MO α / CxeneHb CpoxH odH- N? Ii2 HcnwTyeMbie βολημΑ pacTBop ΘΚΤΗΒ- ΡγΚβΗΗϋ XaMn n-thHyHHa HOCTH HH npH nocjie-KaMH- fly »mHx kjih-9: 1 7: 1 5: 1 o6pa30- ΗΗΗβΟΚΗΧ 06- BaHHH CJieflOBaHHHX (b MecHuax) 1. BOJIBHOf B. + - - cjia6an 27 2 BOJlbHOH Jl. + - - cjia6an 24 3. BOJIHHOH H. + - 'cjiafiaa 29 4. BOJIBHOfi HI. +++ ++ yMepeH-Haa 7 5. BOJIHOHO M. +++ ++ - yMepeHHaH 8 6. BOJIHOHO P. +++ ++ - yMepeHHan 8 7. BOJIHHOH 0. +++ ++ - yMepeHHan 7 8. BOJIBHOf K. +++ ++ - yMepeHHaH 9 9. BOJIbHOf c. +++ ++ - yMepeHHan 8 10. BOJIbHOf y. +++ ++ - yMepeHHaH 7 11. BOJIHHOFF A. +++ +++! +++ BbipajKeHHaH 3 12. BOJIbHOf fl. +++ +++ +++ Bbipa ^ eHHan 2 ΠΡΗΜΕ ^ ΑΗΗΕ: (+) - HajiHMH © θληηημηηχ KpHCTajlJlOB b KpaeBOfi 3θΗβ npo6w

(++) “KOHrJIOMepaTbl KpHCTajlJlOB (+++) - CnJIOmHaH KpHCTaJlJIH3aiJHH KpaeBOfi 30HbI. δ

TafijiHua 2

KjTHHHMecKHe η jiaGopiopHbie itaHHbie y npaKTHvecKH 3flOpOBbIX JIKJflefi B flOKJTHHH ^ eCKOfl CTaflHH ypOJIHTHa3a IPIP ΠΠ

Koji-bo o6cjiao- BaHHbIX jiKmeft

CooTHomeHHe Mona / BOflHbiii pacTBop ajn 6yMHHa_ 9: 1 7: 1 5: 1

CTeneHb?

CpOKH 06-Hapy «eHHH KaMHH ΠρΗ ΠΟ-cjiaywmHX kjih-ηη ^ θοκηχ 06-cjreflOBaHH ^ x (b MecHuax) 1 61 + - - cjia6a # 24-30 2 49 +++, ++ - yMepeHHax 7-8 3 18 +++ +++ +++ BbipajKeHHan 2-3 ΠΡΗΗΕΜΑΗΗΕ: (+) - HajiHHHe θαηηημηηχ KpHCTajijiOB b KpaeBOft 30ΗΘ npofibl

(++) - KOHrjīOMepaTb! KpHCTaJUIOB (+++) - cnjionmaa KpHCTajjjiH3auHH KpaeBoft 30hw.

Kax bhjjho H3 pe3yjibTaTOB / npeflCTaBJieHHbix b Ta6jmuax 1 h 2, BbiHBJieHO 100% cooTBeTCTBHe Me »AY jia6OPTHHMMH h KJiHHH ^ ec-KHMH LieHHblMH, yKa3bIBai0mHMH Ha 06pa30BaHHe Κ3ΜΗΗ. y OflHOft rpjnb 6ojibHbix-KaMHeBbifleHyJeS c BbipajKeHHOft cTeneHbio axTMB-HOCTH KaMHeo6pa30BaHHH (nOJIHOH KpHCTJIH3aHHa KpaeBOfl 30Hbl) Ha6HnOiHi6BaHHe KaMHefi nepe3 2-3 Mecnna; y npyroft - c? acTH? HO? KpHCTi? y TpeTbeft rpynnbi, c θηηηημηβι-mh KpncTajiJH b icpaeBofl 3ïηθ (cjia6aa CTeneHb xaMHeo6pa30Ba-hhh) HaejironaHH βο3ηηκηοβθηη6 KaMHefl nepe3 2-2,5 rona. ToxicMaMe MoCa3aTb ο κπηηηηθοκηχ h jia6opTopHbix naHHbix npax-THMeCKH 3flOpOBbIX JTKJfleii B flOKJIHHHHeCKOfl CTHalHH ypOJIHTHa3a 9-LV 10537 (Ta6jiHua 2). Aκημ o6pa30M, 3aHBJiHeMbifl cnoco6 πο3ΒθπΗβτ cae-jiaTb 3aKmo ieeHHe 06 ηητθηοηβηοοτη npouecca KaMHeo6pa30BaHH% (BblHBHTb KKTHBHOCTH) ΗO CpOKaX < OiJHOBpCMCHHO C BblilB JICIIHCM CTCriCIIH aKTHBHOCTH Κ3ΜΗΘθβ- pa30BaHHH y 13, .6ολ & ημχ ypojiHTHa30M (c ycTaHOBjieHHoa Bbipa? KEH-Hoft cTeneHbio KaMHeo6pa30BaHHH) npoBeneHbi HccjienoBaHHH cocTa-Ba KaMHeo6pa3yionjHx cojieft. H3 yKa3aHHbix 13 6ojibHbix: 6 6ολβηηχ 6blJIH KaMHeBblfleJIHTeJIH, 7 60JIbHbIX 6bIJIH ΠΟΗΒθρΓΗγτω JIHTOTpHnCHH. H3 BbicyraeHHOft Ha npejmeTHOM στβκηβ προ6ω, b κοτοροή 6biJia ποπ-Haa KpHCTajiJiH3auHH KpaeBOH 30hh (cBHneTejibCTByiomaH o HajinmiH Bbipa ^ eHHOfl ΟΤΘΠβΗΗ Κ3ΜΗβθ6ρ330Β3ΗΗΗ) ΠρΟΒβΠβΗΟ c noMombio ρθΗΤΓβκοοτργκτγρΗΟΓο anann3a, peHTreHocneKTpa ^ bHoro MHKpoaHa-jiH3a onpeneJieHHe $ a30Boro hjih sneMeHTHoro cocxaBa βτηχ κρκο-TajiΒΗΗβοκΗΧ 06pa30BaHHfl . nojiyueHHbie naHHbie sJieMeHTHoro (< j > a30-βογο) CocoaBa xpncTa; uHHecKHx 06pa30BaHHft KpaeBoS 30HM npo6 CpaBHHBajlH C flaHHbIMH aHaX! H3a Bb! Pe3yjibTaTbi HccjiaoBaHHft npencTaBJieHbi b TafijjHije 3.

TafijiHua 3

CpaBHHTheibHbie naHHbie aHiHaA cOiBoroCoTaBa KpHCTajuiH ^ ecKHx o6pa30BaHHft Kpaeeoft 30Hbi npo6bi MOHH H BbIiIiHHblX MOH £ BbIX ΧβΜΗβή IP (P ΠΠ

HcnwTyeMbie flHarH03

CocTaB (sjieMeHT- CocTaB BbinejieH- HblH t φ330ΒΜΗ) HblX ΜΟΗβΒΗΧcojieft KpHCTan- KaMHeft (npeo6- ληηθοκηχ o6pa- jranaHHe cojieft 30BaHHft Kpae-ΠΟΠΟΠΟΒΧΗΟΟΤΧΗΟΟΤΧΗΟΟΤ BOft BOF 30HbI npO-HOMy CJIOK)) 6bl MOMH 1 2_3_4 5 1 BonbHoft K. Monexa- MoneBan khcjio- ypaTbi MSHH3H TaX ^ OJie3Hb 10 10 4 2 BojifeHOft Π

3. Bojibhah X χ MoneBan KHCJioTa

7 EOJYHHOE H φοσφορ, icajTbUH, «HHK **

9. BojibHOft A MoueKaMeHHaH φΟΟφΟρ, KajIBUHfl, 60Jie3Hb .XX MarHHH Mo ^ eKaMeHHaH XX φΟΟφΟρ, KajIbllHH * '60Jie3Hb XX 12 3 χ

MotieicaMeHHaH MoneBaji KHCjiOTa 6ojie3Hb KHCJii ypaT

aMMOHHH

MoueKaMeHHan MoweBan KHCJioTa 6ojie3Hi > KHCJibift ypaT

aMMOHHH 4 EojibHOft Jl. Μομθκβμθηκβη 6ojie3H &

5 BojibHOH P. MOMEKaKeHHa KaJi & TiHi ^ φοσφορ 60Jie3HB MarHHH BTOpHHHblft ΠΗΘΠΟΗβφρΗΤ 6 BojibHOft A. MoneKaMeHHaH ΚΗΠΒΗΗβ, φοοφορ 60Jie3Hb MarHHfl BTOpHMHblfl ΠΗΘΛΟΗβφρΗΤ

MoveKaMeHHaH 6ojie3Hb BTOpHMHblft ΠΗΘΛΟΗβφρΗΤ 8 EojibHoft B. Mo ^ eKaMeHHaH φοσφορ, Kajībunft 60Jie3Hb BTOpHMHblft ΠΗβπΟΗβφρΗΤ

10 BojibHOft H 11 BojibHoS Γ. MoMeKaMeHnaa KajībUHft 60Jie3Hb BTOpHHHMĀ ΠΗβΛΟΗβφρΗΤ 12 BojibHOft T. MoMejcaMeHHaH KajībUHft 6ojie3Hb BTOpHMHblH ΠΗβΒΟΗΘφρΗΤ 13 BojibHofl A. MoMeKaMeHHaji KajībUHft 6ojie3Hb BTOpHHHblfl ΠΗβΛΟΗβφρΗΤ _5_ ypaTbi ypaTM ypaTbi < POC $ > Sun φΟΟφΆΤΜ φοοφβτω φΟΟφΒΤΒΙ φΟΟφΗΤΝ φθθφ3ΤΜ OKcanaTbi OKcajiaTbi OKcajiaTbi - 11 - EN 10537 x flainisie ρθΗΤΓβΗοστργκτγρΗΟΓΟ aHajiH3a xx naHHiFaE peHTreHoeneKTpajībHoro MHKpoaHajiH3a *

Kax BHflHO H3 pe3yjibTaTOB, npeflCTaBJieHHbix b TagjiHue 3 aaHHbie aHajiH3a cocīaBa KpHCTajuiHqecKHx o6pa30Ba-HHfi KpaeBOft 30HbJ npo6bl MOHH COOTBeTCTByiOT flaHHbIM, ΠΟΠγΗβΗΗΜΜ ΠρΗ HCCJienOBaHHH COCTaBa μο ^ ιθβογο K3MHH.

TaKHM O6pa30M, 3aHB JIH6MbIH CnOCOS Π03Β0ΠΗβΤ npencKa3aTb hjih onpeflejiHTb cojieBOfl cociB KaMHH Ha ηοκπηηημθοκηχ 3Ta-nax3BHTHH ypojiHTHa3a, ^ το μοτκθτ 6ωτ £ > Hcnojib30BaHO flJiH npe-flOTBpameHHH 06pa30BaHHH ΚΟΗΚρβΜβΗΤΟΒ.

Hjih jiymnero ποηημθηηη HacTOHmero Η3θ6ρβτβΗΗΗ πρηβολητ-ch cjīeflyioiuHe npHMepbi κοηκρθτημχ BapnaHTOB πρκΜβΗβΗΗΗ 3anBJieH-ηογο cnoco6a. ΠρΗΜβρ 1. ilauHeHT B., 50 Ηβτ, HaxoflHJiCH no «Ha6juofleHHeM KJiHHHMec-KOflH6PTOHH B ΤβΜβΗΗβ 2-Χ JI6T · Bbiji B3HT clone flHHaMHMeCKOe Ha6jiwaeHH nocne BbiBejeHHH KaMHH H3 opraHH3Ma. npoBOHHiocb ejKeHenejibHoe HccjieaoBaHHe momh 3aHBJiH6MbiM cnoco6oM. MeTOflHKa HccjieuoBaHHH 3aKHWHajiacb β tom, mto b npo6y Momi ββοηηπη βοπ-Hbift pacTBOp 6eIk b οοοτηοιπθηηη 9: 1, 7: 1 hjih 5: 1 cooTBeTCT-ΒΘΗΗΟ. KanJIH ΠΟΗγΗβΗΗΟΗ CM6CH HaHOCHJIH If ΠρθΠΜΘΤΗΟβ CTSKJIO h BbicymHBajiH πρκ κομη3τηοη TeMnepaType β τβπβΗΗβ 24 MacoB. 3aTeM is the mainHHH xapaKTep KpHCTajuiH3auHH cojieii β xpaeBoft 30-He npofibi. Ha προτπκβΗΗΗ Ηβτωρβχ MecnueB 6b »and Bbip« eHHaH στβ-neHb aKTHBHOCTH KaMH € 0 6pa30BaHHH (nOJIHan KpHCTaJlJIH3ai4HH Kpae-BOfi 3 0Hbl npofibl). ΟΗΗΟΒρθΜΘΗΗΟ C nOMOIHblO ΟΠΘΚΤρβΠΒΗΟΓΟ MHKpO-aHaHH3a BblHBJieH 3JieMeHTHblO COCTaB KpHCTaJTJIHHeCKHX 06pa30BaHHfi KpaeBOft 30Hbi. fljin cpaBHHTejibHoro aHajTH3a οπηοβρθμθηηο npoBe- 12 ΛΘΗΟ onpeflejreHHe sjieMeHTHoro cocTaBa ueHTpajibHoU 3ohw npo6bi. 3Ha ^ HTejibHoe πρβΒωιπβΗΗβ conep »aHHH OTflejibHbix 3jieMeHTOB b Kpae-Bofi. 30Hef OTHOCHTejibHO ueHypHofl cocTaBjiseT ocHOBy KaMHe-o6pa3ywmHX cojiefl.

Pe3yjibTaTbi onpeflejieHHH cocTaBa KaMHeo6pa3ywmHx cojieft noflTBep? KfleHbi aHaHiM30M cocTaea KaMHH nocjie difference βηβθλθηηη H3 opraHH3Ma. Pe3yjibTaTbi HccjieflOBaHH and npeacTaBJieHbi b Ta6jimie 4.

TaCjiHua 4 flaHHbie cpaBHHTfijrbHoro aHajiH3a sjieMeHTHoro cocTaBa ueHTpajiHofl h KpaeBoft 3oh npo6bi momh h BbinejieHHoro

ΜΟ ^ ΙβΒΟΓΟ K3MHH

SjieMeHTbi, B% ΠΠ MaTepnaJi Na Mg PS 1 K Ca Zn Si 1 R 6 Mo 1 H (ue H 2b) -Ha 30 Ha 27.4 1.1 3/4 1.1 62.6 3.3 - 2 Ilpo6a MoqH (KpaeBaa 30Ha) 17 , 3 0.9 14.6 9.5 39.6 11.6 6.1 - ·· 3 BbinejieHHbiH MoqeBo0 • KaMeHb 3.3 30.3 - 64.2 -

Kax BHflHO H3 naHHbix Ta6jiHUbi 4 3Ji6M6HTaMH KaMHeo6pa3yio-ΠΙΗΧ COJieft HBJIHIOTCH C Η P, qTO ΠΟΛΤΒβρ * ΒΘΗΟ COCTaBOM KaMHH (nocjie BbiBeaeHHH ero H3 opraHH3Ma. Nocjie BbiBeneHHH Κ3μηη H3 opraHH3Ma nauHeHTy Ha3HaqeHO MeaHKaMeHT03Hoe λθμθηηθ h nponojiaceHO ejKeHeaejibHoe HCCJienoBa-HCE Moqw 3aHBJieHHbfM cnocodOM, κοτοροθ npoBOBHJiocb b TeqeHne neyx Λβτ. JlHHaMHqecKoe Ha6jnoneHHe (nepHOflHqecKoe is the mainThe CTeneHH aKTHBHOCTH KaMHeo6pa30BaHHH)

Ta6jimja 5

Pe3yjibTaTW na6iDiHHX 3a aKTHBHOCTbio npouecca KaMHeo6pa30BaHHH y 6oji & Horo B. b βηηβμηκθ nocne Ha ^ ajia they ^ eHHH

IlepHonbi Hccjie- HOBaHHH

ΠθΚ333ΤβΛΗ KpHCTaj1JH3aUHH KpaeBoii 30hw npo6w momh CTeneHb aHTHH-ΠρΗ COOTHOtHHH MOMa / BOfl- HOCTH ΚβΜΗβΟβ-Hbif pacTBOp anb6yMHHa_BoHHHH 9: 1 «7: 1 5: 1

1 HenejiH ++ ++ - yMepeHHaa 1 ΜβΟΗΠ + + - cjia6an 2-4 MecHua - - - npouecc OTcyT - CTByeT 5-7 MecHueB ++ + - yMepeHHaa 8 MecHueB + - - cjiafiaH 9-13 MecHueB - - - npouecc oTcyx— cTByeT 14 M6CHU6B + - - cjiaSaa 15-20 MecaueB + • - - cjiaSaa ΠΡΗΜΕΜΑΗΗΕ: + - HajiHMHe eflHHHHHblK KpHCTajIJIOB

++ - KOHRJIOMepaTbl KpHCTajIJIOB - - OTcyTCTBHe KpncTajuiOB ΠρΗΜβρ 2.

OnpeflejreHHe CTeneHH βκτηβhocth KaMHeo6pa30BaHHH b προ-

J 6e MOMH δΟΛΒΗΟΓΟ X. ΠρΟΒΟΠΗΤ ΘΗΒΛΟΓΗΜΗΟ OnHCaHHOMy B ΠρΗΜΘ-pe 1. Onpee jieHa BbipajKeHHa CTeneHb aKTHBhocth KaMHeo6pa30-BaHHH (nojTHaa KpHCTyJiH3auHH KpaeBoii 30hw npo6bi). C πομοήβιο peHTreHOCneKTpajībHOrO MHKpOaHajIH3a BblHBJIHKJT ΒΗβΜβΗΤΗωίί coc-TaB KpHCTajijiHMecKHX o6pa30BaHHfi KpaeBoft 3ohbi. ITposeneH cpae-HHTejibHbift aHajiH3 3JieMeHTHoro cocTaBa KpaeBoft h ueHTpajībHOft 14 3θΗ BbicyraeHHoA προβω momh. Pe3yjibTaTbi οπρβηβΛθΗΗΛ cocTaBa KaMHeo6pa3yiomHX cojiefi ποητΒβρκπθΗΜ aHajiH30M cocTaBa KaMHH nocjie difference ββιβθπθηηη H3 opraHH3Ma. Pe3yjibTaTbi HccjiaoBaHHft npencTaBJieHbi b TafiJinue 6.

TaurusHua 6 flaHHbie cpaBHHTSJHBHOR aHajiH3a 3JieMeHTHoro cocTaBa ueHTpOpHiF h xpaeBofl 30H προβω μο * ιη h βηαθλθηηογο

ΜΟΜ6ΒΟΓΟ KaMHH Tfelfe SjieMeHTbl, B% N * trnn MaTepHaji Na Mg C 1 Cl 2 Ca Ca Zn Si 1 R 6 Mo 2 (ue H 1 H 6 H 6) 26.2 2.0 15.1 8.9 30.5 13.0 2, 6 2 npo6a momh (KpaeBan 30Ha) 27.6 2.1 19.6 12.3 26.0 4.8 7.6 - - 3 BbiflejieHHbifl ΜΟ ^ ΘΒΟΗ κθμθηβ 1.5 - 4.1 0.5 - - 93 , 0 -

Kax BHziHO H3 flaHHbix Ta6nHUb 6, sJieMeHTOM xaMHeo6pa3yw-WHX COJEi HBJIH6TCH B OCHOBHOM Ca, MTO ΠΟΛΤΒθρ? ΚηβΗΟ COCTaBOM KaMHH: Ca - 93%. ΠρΗΜθρ 3. it

OnpeflejieHHe · οτθπθηη βκτηβηοοτη KaMHeo6pa30BaHHa b ITO-6e MO ^ JH 60JIbH0r0 K. npOBOflHT aHaJIOrHUHO onHcaHHOMy B NPH-mepe 1 OnpeflejieHa BbipajKeHHaH οτθπθηβ 3κτηβηοοτη KaMHeofipa-30BaHHH (nOJIHan KpHCTajIJlH3aUHH KpaeBOft 30HbI npo6bl). C nOMOmbH) peHTreHoeneKTpajībHoro MHKpoaHajiH3a BbiflBJiHtoT 3JieMeHTHbift coc-Tae KpHCTajrjiHMecKnx o6pa30BaHHft KpaeBoii 30Hbi. Προβθπθη cpaBHH-TejibHbift aHajiH3 θπθμθητηογο cocTaBa KpaeBOft h ueHTpajibHofl 30H - 15 - EN 10537

BbicymeHHofi npo6M momh. Pe3yjifaTaTbi onpenejieHHH cocTaBa KaMHe-o6pa3yioinHX cojiefl noHTBepjKueHbi cocTaeoM KaMHJi nocne difference Bbrae-fleHHHH3 opraHH3Ma. Pe3yjibTaTbi HCCJienoBaHHa npencTaBjieHbi b Ta6jiHue 7.

Ta6jiHua 7. flanHbie cpaBHHTejibHoro aHajiH3a ajieMeHTHoro cocTaBa ueHTpajibHoft h jcpaeso 30H npo6w mo ^ h h BbiaejieHHoro ΜΟ ^ ΘΒΟΓΟ Κ3ΜΗΗ

MaTepnaji j r SjieMeHTbi, B% Na Mg PS C1 K Ca Zn Si 1 Προ6a mo (ueH-Shi-Han 30Ha) 17.2 15.8 12.2 31.1 19.7 2.6 - 2 npo6a mowh (KpaeBaH 30Ha) 12.7 3.9 23.3 9.2 22.4 12.5 5.5 - - 3 BbinejieHHbif (ΜΟ ^ ΙβΒΟβ KaMeHb) - 14.0 39.3 - - - 44.7 -

KaK BHJIHO H3 «aHHBIX TA6JIHUbI 7, 3JISMSHTaMH KaMHeo6pa3yw- Π1ΗΧ COJieS HBJIHeTCH B OCHOBHOM Ca, P H Mg, MTO nOflTBepeKoE COCTaBOM KaMHJi: Ca - 44.7% j P - 39.3%; Mg - 14.0%. IIpHMep 4.

OnpeziejieHHe οτβπβΗΗ βκτηβηοοτη κημηθο6ρ330Β3ηηλ b προ-6e MOMH SOJlbHOrO C. ΠρΟΒΟΒΛΤ; aHajIOrHMHO OilHCaHHOMy Β ripHMe-pe 1. OnpenejieHa BbipaceHHaji CTeneHb θητηβηοοτη KaMHeo6pa30-BaHHH (nOJIHa ^ KpHCTaJIBH3aqHH KpaeBOfl 30Hbl). C nOMOmbH) SHEETRHOCneKTpajIbHOrO MHKpOaHajlH3a BbtilBJieH 3ΛβΜβΗΤΗΜβ COCTaB KpHC-TajiJiHuecKHX o6pa30BaHHfl KpaeBOfi 30hm. npoBeaeH cpaBHHTejibHbiS aHaji «3 3j € M6HTHoro cocTaea KpaeBofi h neHTpajībHOft 30H Bbicy- 16 tneHHOft προβω mohh. nocjre βμηβ.πθηηη BbipaaceHHOA crenenH axTHB -HocthHMHeo6pa30BaHHH h onpeneneHHH cocTaBa xaMHeo6pa3yK nHx cojieft mohh 6ojibhoh nporaeji Kypc HHnHBHnyanbHOĀ TepanHH. Pe-3yjibTaTbi HcenenOBaHHi: npencTaBneHbi b Ta6jiHqe 8.

TafijiHiia 8 flaHHbie cpaBHHTejibHoro aHajiH3a 3λθμθητηογο cocTaBa ueHTpajeboFlf KpaeBOfl 30H npo6w mohh h BblflejieHHOrO ΜΟΗβΒΟΓΟ KaMHH (b%) flepHOfl CTeneHb

Hccjie- aKTHB-ZIOBa- HOCTH MaTepnan SneMeHTbi, Na Mg PS C1 K Ca Zn Si HHH KaMHe6pa30 -BaHHH no-Bbipanpo6a MO- KJKHHhh (ueH-Han TpanbHan 1.530Ha) 25/27, 1 7.8 37.1 16.4 1.7 0.2 - προ6a MO-hh (xpae-B3H 30- 0.2 na) 14.1 14.6 2.7 17.0 8.4 4.7 0.2 - nocne προ- • npo6a MOnen necc HH (ueHT - HHH OTCyT - panbHan 1.0 10.1 CTByeT 30Ha) 33.4 10.6 35.9 7.1 1.4 1.3 - Προ6a Mo -hh (icpae - Ban 30Ha) 34.6 - 10.6 8.3 35.9 6.4 0.4 1.1 -

Kax bhziho H3 Ta6iiHUbi 8, BJieMeHTaMH KaMHeo6pa3ytomHX co-neft (no πθηθημη) ηβηηιοτοη Ca η P; nocne jieqeHHH nponecc xaM-Heo6pa30BaHHJi OTcyTCTByeT. - 17 - EN 10537

ΦΟΡΜΥΙΊΑ H30BPETEHHH 1 Cnoco6 onpenejieHHH CTeneHH aKTHBHOCTH KaMHeo6pa30Ba-hhh h cocTaea KaMHeo6pa3yiomHx cojieft μομη πρκ ypojiHTHa3e, OTJIHMaroniHftCH ΤβΜ, HTO B npo6y ΜΟΊΗ BBOflHT BOfl-Hbift solution was 6ejixa b οοοτηοπιθηηη 9: 1, 7: 1 hjih 5: 1 σοοτΒβτστ-bshho, nojiy ^ eHHyio CMec & b BHne KanjiH HaHOCHT Ha poBHyio no-BepxHOCTb h BbicyniHBaiOT b TeueHHe not μθηθθ 24 MacoB, 3aTeM οπρβββΛΗΐοτ xapaKTep KpHCTajuiH3auHH cojiefi b KpaeBoft 3θΗθ ITO-6bli NPH HajIHHHH eflHHHUHWX KpHCTaJIJIOB, HX KOHrjIOMepaTOB HJIH nOJIHOft KpHCTajJJIH3aUHH 3TOft 30HbI CyflHT ΟΟΟΤΒβΤΟΤΒβΗΗΟ O CJia-6ofi, yMepeHHOfl hjih BbipJKeHHiii CTeneHH aiCTHBHocTH xaMHeo6pa-30Β3ΗΗΗ; BblHBJIHHJT COCTaB 3ΤΗΧ KpHCTajIJIHtieCKHX 06pa30BaHHfi C OJļHOBpeMeHHbIM ΟΠρβΛβΠβΗΗβΜ COCTaBa COJieft IļeHTpaJIbHOfl 30HbI npofibf H nOCJieflyWniHM ΠρΟΒβ, ΠβΗΗβΜ CpaBHHTeJIbHOrO anaJIH3a 3ΤΗΧ cocTaBOB fljtH onpenejieHHH KaMHeo6pa3ywmHX conefl mohh. 2. Cnocoe ΠΟ Π. 1, OTJIHHaiomHftCi ΤβΜ, ΗΤΟ b KanecTBe βοπηογο pacTBopa 6ejixa Hcnojib3ywT 8-12% -Hift boh-Hbifl pacTBop ajib6yMHHa. 3. Cnoco6 non.l, OTjiH ^ aiomHftcH τθμ, hto bbi-cymHBaHHe HaHeceHHofi Ha poBHyw nOBepXHOCTb KanjiH nojiyueHHOii CMecH npoBOHHT πρκ KOMHaTHOii TeMnepaType. 4. Cnocoe no Ji 6oMy H3 NYHKTOB 1-3, OTJiHHaionHft-C X ΤβΜ, HTO flJIH BblHBJISHHH ΒΙΙβΜβΗΤΗΟΓΟ COCTaBa KpHCTaJIJIH-ΜβσκΗΧ odpa30BaHHi Hcnojtb3yioT peHTreHoeneKTpajibHbift ΜΗκρο-aHajiH3. - 18 - EN 10537 ι.

P E Φ E P A T

Cnocoā onpeflejieHHH CTeneHH aKTHBHocTH KaMHeo6pa30BaHHfl h cocTaBa KaMHeo6pa3yiomHx cojiefl mohh πρκ ypojiHTHa3e 3aKJiro-qaeTCH b tom, ίτο, .b npo6y Mouh bbobht BojiH & ift solution was 6ejiKa b cooTHomeHHH 9: 1, 7: 1 hjih 5: 1 σοοτΒβτστΒβΗΗΟ, nojiyHeHHyw CMEC "HaHocaT H poBHyio noBepxHocTb h BbicymHBaioT b τβπβΗΗβ cyTOK, 3aTeM onpeflejiHMT xapaxīep KpHCTajiJiH3auHH cojieči b KpaeBoS 3θΗβ np06blf ΠρΗ HaJIHtIHH βΗΗΗΗΗΗΗΧ KpHCTajIJIOB, ΗΧ ΚΟΗΓΛΟΜβρβΤΟΒ HJIH nOJIHOft KpHCTaJIJIH3aUHH 3TOtf 30HBI CynHT a respective O-CJia 6oft, yMepeHHOft η BbipajKeHHOii CTeneHH aKTHBHOCTH KaMHeo6pa30-BaHHH; BblHB JIHKJT COCTaB 3ΤΗΧ KpHCTaJIJIHHeCKHX 06pa30BaHHŪ C OFL-ΗΟΒρβΜβΗΗΗΜ ΟΠρβΠβΙΙβΗΗβΜ COCTaBa COJiefl UeHTpajIb HoA 30HbI Πρθ "6m h nocjienyioinHM npoBejtisHHeM cpaBHHTejibHoro aHajiH3a sthx CoC-TaBOB iuiH onpeaejieHHH KaMHeodpa3yioiiiHX cojiefi mohh. »

Claims (4)

Method of Invention 1: A method for determining urine-forming activity and composition of urethral-forming salts in the case of urolithiasis, characterized in that the aqueous solution of protein in the urine sample is added in a ratio of 9: 1, 7: 1 and 5: 1, respectively, to the resulting mixture. applying a drip on a smooth surface and drying for not less than 24 hours, then determining the crystallization character of the salts in the sample edge area; in the case of individual crystals, in the case of their conglomerates or in the case of complete crystallization of the zone, it is concluded that the activity of weak, medium or pronounced urethral formation is low; determines the composition of these crystalline formations and at the same time determines the composition of the centrifugal zone of the sample, after which the comparative analysis leads to the conclusion of the composition of the salts forming the urethra. Method according to claim 1, characterized in that 8-12% by weight of an aqueous solution of albumin is used as an aqueous solution of the protein. Method according to claim 1, characterized in that drying of the droplet of the mixture on a smooth surface is carried out at room temperature. 1 Method according to any one of claims 1-3, characterized in that X-ray microanalysis is used to determine the composition of the crystalline forming elements. 2