LU102061B1 - Device for removing intravascular lipids - Google Patents

Device for removing intravascular lipids Download PDF

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Publication number
LU102061B1
LU102061B1 LU102061A LU102061A LU102061B1 LU 102061 B1 LU102061 B1 LU 102061B1 LU 102061 A LU102061 A LU 102061A LU 102061 A LU102061 A LU 102061A LU 102061 B1 LU102061 B1 LU 102061B1
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LU
Luxembourg
Prior art keywords
mesh
substance
cavity
sieve
catcher
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Application number
LU102061A
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German (de)
Inventor
Ting Xu
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Jiangsu Cancer Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2/0103With centering means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgical Instruments (AREA)
  • External Artificial Organs (AREA)

Abstract

The present invention discloses a device for removing intravascular lipids, which comprises at least one catcher. The catcher comprises a mesh and a sieve body. The mesh is provided with a mesh cavity and a catching inlet communicating with the mesh cavity. The mesh is adapted to sieve a first substance entering from the catching inlet to leave a second substance in the mesh cavity, the sieve body is provided in the mesh cavity, and the sieve body is provided with a screening body and a storage cavity adapted to store a third substance obtained after the second substance is screened by the screening body. The present invention can quantitatively eliminate specific lipids in blood vessels without other adverse effects on their metabolic pathways, and can safely and efficiently inhibit the phenomenon that specific lipids are oxidized and hoarded on blood vessel walls.

Description

DEVICE FOR REMOVING INTRAVASCULAR LIPIDS TECHNICAL FIELD
[0001] The invention relates to a device for removing intravascular lipids.
BACKGROUND
[0002] At present, hyperlipidemia is a common clinical disorder of lipid metabolism, which usually refers to the increase of cholesterol (or) triglycerides in plasma, which easily results in diseases such as coronary heart disease and atherosclerosis. The level of blood lipids is closely related to daily dietary intake and lipid metabolism in the body. Due to the changes in modern lifestyles, such as excessive or unbalanced nutritional intake, office workers sitting in the office for a long time so that the amount of exercise is insufficient, with changes in the pace of life and diet structure, the incidence of hyperlipidemia is rising sharply, which seriously threatens human health.
[0003] At present, western medicines commonly used to treat hyperlipidemia on the market comprise statins, fibrates, etc., as well as proprietary Chinese medicines such as Xuezhikang, Jiangzhiling and Zhibituo. Although the lipid-lowering drugs have achieved great effects, most lipid-lowering drugs are prone to cause various side effects: for example, taking statins will cause adverse reactions such as increased serum transaminases and muscle aches; it more likely for those taking clofibrate to develop gall-stones or tumors; taking other proprietary Chinese medicines, etc, will also cause a burden on the liver in the long run and require a higher cost for long-term use.
[0004] No matter which method is used to lower blood lipids, it is to inhibit the formation of lipids to achieve the purpose of lowering lipids, which will bring greater side effects. At present, no effective method or device for rapidly lowering lipids after formation of cholesterol (or) triglycerides has been developed. The deposition of lipids is controlled at the terminal, thereby reducing the chance of modern people suffering from cerebral cardiovascular diseases.
SUMMARY
[0005] The technical problem to be solved by the present invention is to overcome , 1
I the shortcomings of the prior art and provide a device for removing intravascular lipids, which can quantitatively eliminate specific lipids in blood vessels without other adverse effects on their metabolic pathways, and can safely and efficiently inhibit the phenomenon that specific lipids are oxidized and hoarded on blood vessel walls.
[0006] In order to solve the above technical problems, the technical solution of the present invention is a device for removing intravascular lipids, comprising:
[0007] at least one catcher, wherein the catcher comprises a mesh and a sieve body, the mesh is provided with a mesh cavity and a catching inlet communicating with the mesh cavity, the mesh is adapted to sieve a first substance entering from the catching | 10 inlet to leave a second substance in the mesh cavity, the sieve body is provided in the | mesh cavity, and the sieve body is provided with a screening body and a storage cavity | adapted to store a third substance obtained after the second substance is screened by the screening body.
[0008] Further, the device further comprises an axis of rotation; wherein
[0009] the catcher is installed on the axis of rotation, and the catcher is adapted to follow the axis of rotation under the action of blood flow in the blood vessel to rotate with the axis of rotation as the center.
[0010] Further, during the rotation of the catcher, at least one position causes the catching inlet to face the blood flow direction in the blood vessel.
[0011] Further, the mesh comprises:
[0012] a square bracket forming the catch inlet;
[0013] an arc-shaped bracket connected to the square bracket;
[0014] at least part of molecular sieves attached to the square bracket and the arc-shaped bracket and covering the rest of the mesh except for the catching inlet. |
[0015] Further, the molecular sieve is made of a gel material with a three-dimensional network structure.
[0016] Further, the sieve body further comprises a transfer tank, the transfer tank is provided with at least one discharge port extending out of the mesh, the second substance first passes through the transfer tank and then passes through the screening body, and the discharge port is adapted to discharge substances in the second substance 2 that have not passed through the screening body.
[0017] Further, the bottom of the transfer tank is a screening body, and the top of the storage cavity is a screening body.
[0018] Further, the middle part of the transfer tank is higher than the two ends.
[0019] Further, the screening body is made of gel material with a three-dimensional network structure. | [0020] Further, the mesh is adapted to screen out other substances in the first substance smaller than the second substance;
[0021] the screening body is adapted to screen out other substances in the second substance larger than the third substance.
[0022] After adopting the above technical solution, the present invention can catch the second substance from the first substance in the blood vessel through a mesh, and then use the screening body to screen out the third substance in the second substance, and store the third substance in the storage tank. After being stored in the storage tank, the third substance is then taken out together with the device. Through the above structure, the specific lipids in blood vessels can be eliminated, which is very convenient to use.
BRIEF DESCRIPTION OF THE DRAWINGS
[0023] FIG. 1 is a schematic diagram of the structure of a device for removing intravascular lipids according to the present invention;
[0024] FIG. 2 is a perspective diagram of a catcher according to the present invention.
DESCRIPTION OF THE EMBODIMENTS
[0025] In order to make the content of the present invention easier to be understood clearly, the present invention will be further described in detail based on specific embodiments in conjunction with the accompanying drawings hereinafter.
[0026] As shown in FIGS. 1 and 2, a device for removing intravascular lipids comprises: 3
[0027] at least one catcher 1, wherein the catcher 1 comprises a mesh 11 and a sieve body, the mesh 11 is provided with a mesh cavity and a catching inlet 11a communicating with the mesh cavity, the mesh 11 is adapted to sieve a first substance entering from the catching inlet 11a to leave a second substance in the mesh cavity, the sieve body is provided in the mesh cavity, and the sieve body is provided with a screening body 12 and a storage cavity 13 adapted to store a third substance obtained after the second substance is screened by the screening body 12.
[0028] As shown in FIG. 1, the device for removing intravascular lipids further comprises an axis of rotation 2; wherein
[0029] the catcher 1 is installed on the axis of rotation 2, and the catcher 1 is adapted to follow the axis of rotation 2 under the action of blood flow in the blood vessel to rotate with the axis of rotation 2 as the center.
[0030] In this embodiment, the number of the catchers 1 is but not limited to three, which are evenly distributed along the circumference of the axis of rotation 2.
[0031] During the rotation of the catcher 1, at least one position causes the catching inlet 11a to face the blood flow direction in the blood vessel.
[0032] As shown in FIG. 2, the specific structure of the mesh 11 may be the following structure, comprising:
[0033] a square bracket 11b forming the capture inlet 11a;
[0034] an arc-shaped bracket 11c connected to the square bracket 11b;
[0035] at least part of molecular sieves 11d attached to the square bracket 11b and the arc-shaped bracket 11c and covering the rest of the mesh 11 except for the catching ' inlet 11a.
[0036] Specifically, in this embodiment, both sides of the arc-shaped bracket 11c are connected to both sides of the short sides of the square bracket 11b, and one of the short sides of the square bracket 11b is connected to the axis of rotation 2; the arc-shaped bracket 11c may be an arched structure.
[0037] In this embodiment, the arc-shaped bracket 11c on the opposite side of the square bracket 11b and the two sides in which the square bracket 11b and the arc-shaped bracket 11c are connected all cover the molecular sieve 11d. 4
EEE
[0038] The molecular sieve 11d may be made of a gel material with a three-dimensional network structure.
[0039] Specifically, as shown in FIG. 2, the sieve body further comprises a transfer tank 14, the transfer tank 14 is provided with at least one discharge port extending out of the mesh 11, the second substance first passes through the transfer tank 14 and then passes through the screening body 12, and the discharge port is adapted to discharge substances in the second substance that have not passed through the screening body 12.
[0040] In this embodiment, the entire sieve body can be fixedly connected in the mesh 11 by the supporting bracket 3.
[0041] Specifically, as shown in FIG. 2, the bottom of the transfer tank 14 is a screening body 12, and the top of the storage cavity 13 is a screening body.
[0042] Specifically, as shown in FIG. 2, the middle part of the transfer tank 14 is higher than the two ends, which facilitates the discharge of substances that have not passed through the screening body 12 to the discharge port.
[0043] Specifically, the screening body 12 may also be made of a gel material with a ; three-dimensional network structure.
[0044] In addition, in this embodiment, the mesh 11 is adapted to screen out other substances in the first substance smaller than the second substance;
[0045] the screening body 12 is adapted to screen out other substances in the second substance larger than the third substance.
[0046] In this embodiment, according to the size of the third substance to be collected, the mesh 11 and the screening body 12 with corresponding apertures can be selected.
[0047] The axis of rotation 2 and the catcher 1 are driven to rotate together under the action of blood flow in the blood vessel. During the rotation, the first substance enters from the catching inlet 11a, the first substance is screened through the mesh 11, the second substance with the aperture larger than the mesh 11 remains in the mesh cavity, and other substances with the aperture smaller than the mesh 11 are screened out. The \ second substance entering the mesh cavity first enters the transfer tank 14, and then passes through the screening body 12. The third substance with the aperture smaller 5
EE than the screening body 12 is screened out into the storage cavity 13, and other 10106081 substances in the second substance with the aperture larger than the screening body 12 are discharged from the discharge port, thereby realizing the collection of specific lipids (that is, the third substance).
[0048] The specific embodiments described above further describe the technical problems, technical solutions and beneficial effects solved by the present invention in further detail. It should be understood that the above descriptions are only specific embodiments of the present invention and are not intended to limit the present invention. Any modification, equivalent replacement, improvement, etc. made within | the spirit and principle of the present invention shall be included in the protection scope of the present invention.
[0049] In the description of the present invention, it should be understood that the terms indicating the orientation or the positional relationship are based on the orientation or the positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the indicated device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present invention.
[0050] In the present invention, unless otherwise clearly defined and limited, the terms "install", "link", "connect", "fix" and the like should be understood in a broad sense, for example, it may be a fixed connection or a detachable connection, or may be integrated; it may be a mechanical connection, or may be an electrical connection; it may be a direct connection, or an indirect connection through an intermediate medium, and it may be the internal communication of two elements or the interaction relationship between two elements. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0051] In the description of the present invention, it should be noted that the orientation or position relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or position relationship shown in the drawings, or the orientation or position relationship usually placed when the product of the present invention is used, and is 6 + mau only for the convenience of describing the present invention and simplifying the Fier description, rather than indicating or implying that the indicated device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first", "second", "third", etc. are only used for distinguishing description, and cannot be understood as indicating or implying relative importance.
[0052] In addition, the terms "horizontal", "Vertical", "overhanging" and the like do not mean that the element is required to be absolutely horizontal or overhanging, but may be slightly inclined. For example, "horizontal" only means that its direction is more horizontal than "vertical", rather than meaning that the structure must be completely horizontal, but can be slightly inclined.
[0053] In the present invention, unless otherwise clearly stated and defined, the first feature above or below the second feature may include the first feature and the second feature in direct contact with each other, or may comprise the first feature and the second feature not in direct contact with each other but in contact with each other through the other features therebetween. Moreover, the first feature above, on, and over the second feature comprises the first feature directly above and obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature below, under, and underneath the second feature comprises the first feature directly below and obliquely below the second feature, or simply means that the first feature is lower in level than the second feature. 7 ee

Claims (10)

Claims
1. A device for removing intravascular lipids, comprising: at least one catcher (1), wherein the catcher (1) comprises a mesh (11) and a sieve body, the mesh (11) is provided with a mesh cavity and a catching inlet (11a) communicating with the mesh cavity, the mesh (11) is adapted to sieve a first substance entering from the catching inlet (11a) to leave a second substance in the mesh cavity, the sieve body is provided in the mesh cavity, and the sieve body is provided with a screening body (12) and a storage cavity (13) adapted to store a third substance obtained after the second substance is screened by the screening body (12).
2. The device for removing intravascular lipids according to claim 1, wherein: the device further comprises an axis of rotation (2); wherein the catcher (1) is installed on the axis of rotation (2), and the catcher (1) is adapted to follow the axis of rotation (2) under the action of blood flow in the blood vessel to rotate with the axis of rotation (2) as the center.
3. The device for removing intravascular lipids according to claim 2, wherein: during the rotation of the catcher (1), at least one position causes the catching inlet (11a) to face the blood flow direction in the blood vessel.
4. The device for removing intravascular lipids according to claim 1, wherein: , the mesh (11) comprises: a square bracket (11b) forming the catch inlet (11a); an arc-shaped bracket (11c) connected to the square bracket (11b); at least part of molecular sieves (11d) attached to the square bracket (11b) and the arc-shaped bracket (11c) and covering the rest of the mesh (11) except for the catching inlet (11a).
5. The device for removing intravascular lipids according to claim 4, wherein: the molecular sieve (11d) is made of a gel material with a three-dimensional network structure.
6. The device for removing intravascular lipids according to claim 1, wherein: 8 "A the sieve body further comprises a transfer tank (14), the transfer tank (14) is provided with at least one discharge port extending out of the mesh (11), the second substance first passes through the transfer tank (14) and then passes through the screening body (12), and the discharge port is adapted to discharge substances in the second substance that have not passed through the screening body (12).
7. The device for removing intravascular lipids according to claim 6, wherein: the bottom of the transfer tank (14) is a screening body (12), and the top of the storage cavity (13) is a screening body.
8. The device for removing intravascular lipids according to claim 6, wherein: the middle part of the transfer tank (14) is higher than the two ends.
9. The device for removing intravascular lipids according to claim 1, wherein: the screening body (12) is made of gel material with a three-dimensional network structure.
10. The device for removing intravascular lipids according to claim 1, wherein: the mesh (11) is adapted to screen out other substances in the first substance smaller than the second substance; the screening body (12) is adapted to screen out other substances in the second substance larger than the third substance.
9
LU102061A 2020-08-20 2020-09-15 Device for removing intravascular lipids LU102061B1 (en)

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Application Number Priority Date Filing Date Title
CN202021750178.5U CN212308118U (en) 2020-08-20 2020-08-20 Intravascular lipid removing device

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LU102061B1 true LU102061B1 (en) 2021-08-26

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Effective date: 20210826