LTIP609A - Multinuclear complexes, contrast media containing them and use - Google Patents

Multinuclear complexes, contrast media containing them and use

Info

Publication number
LTIP609A
LTIP609A LTIP609A LTIP609A LTIP609A LT IP609 A LTIP609 A LT IP609A LT IP609 A LTIP609 A LT IP609A LT IP609 A LTIP609 A LT IP609A LT IP609 A LTIP609 A LT IP609A
Authority
LT
Lithuania
Prior art keywords
media containing
contrast media
complexes
multinuclear complexes
multinuclear
Prior art date
Application number
LTIP609A
Inventor
Arne Berg
Torsten Almen
Klaus Dieter Krautwurst
Sook-Hui Kim
Pal Rongved
Jo Klaveness
Harald Dugstad
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of LTIP609A publication Critical patent/LTIP609A/en
Publication of LT3535B publication Critical patent/LT3535B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic System
    • C07F11/005—Compounds containing elements of Groups 6 or 16 of the Periodic System compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Abstract

The invention relates to the use as contrast enhacing agents in medical imaging, especially X-ray imaging, of multinuclear complexes, i.e. complexes, such as those of W2O2( mu 2O)2, in which the complexed entity comprises at least two contrast enhancing atoms.
LTIP609A 1990-03-28 1993-06-03 Multinuclear complexes, contrast media containing them and use LT3535B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909006977A GB9006977D0 (en) 1990-03-28 1990-03-28 Compositions

Publications (2)

Publication Number Publication Date
LTIP609A true LTIP609A (en) 1994-12-27
LT3535B LT3535B (en) 1995-11-27

Family

ID=10673438

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP609A LT3535B (en) 1990-03-28 1993-06-03 Multinuclear complexes, contrast media containing them and use

Country Status (18)

Country Link
US (2) US5458869A (en)
EP (2) EP0645146A1 (en)
JP (1) JPH06507147A (en)
AT (1) ATE142508T1 (en)
AU (1) AU645796B2 (en)
CA (1) CA2079212A1 (en)
DE (1) DE69122092T2 (en)
DK (1) DK0521977T3 (en)
ES (1) ES2091323T3 (en)
FI (1) FI924297A0 (en)
GB (1) GB9006977D0 (en)
HK (1) HK219596A (en)
HU (2) HU9203086D0 (en)
LT (1) LT3535B (en)
LV (1) LV10056B (en)
NO (1) NO923739L (en)
SG (1) SG43931A1 (en)
WO (1) WO1991014460A1 (en)

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US6838074B2 (en) 2001-08-08 2005-01-04 Bristol-Myers Squibb Company Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
MXPA04001113A (en) 2001-08-08 2004-07-08 Bristol Myers Squibb Pharma Co Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent.
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
US20050106100A1 (en) * 2003-09-03 2005-05-19 Harris Thomas D. Compounds containing matrix metalloproteinase substrates and methods of their use
US7485283B2 (en) 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
JP4322781B2 (en) * 2004-11-08 2009-09-02 富士フイルム株式会社 Imaging device
CA2613439A1 (en) * 2005-06-30 2007-01-11 Bristol-Myers Squibb Pharma Company Hydrazide conjugates as imaging agents
US7824659B2 (en) 2005-08-10 2010-11-02 Lantheus Medical Imaging, Inc. Methods of making radiolabeled tracers and precursors thereof
US9149545B2 (en) * 2005-11-02 2015-10-06 General Electric Company Nanoparticle-based imaging agents for X-ray/computed tomography and methods for making same
US20070098640A1 (en) * 2005-11-02 2007-05-03 General Electric Company Nanoparticle-based imaging agents for X-ray/computed tomography
TW200738752A (en) 2006-01-31 2007-10-16 Bayer Schering Pharma Ag Modulation of MDL-1 activity for treatment of inflammatory disease
EP2257315B1 (en) 2008-02-29 2019-10-23 Lantheus Medical Imaging, Inc. Contrast agents for applications including perfusion imaging
CN102088907B (en) * 2008-07-07 2013-03-27 皇家飞利浦电子股份有限公司 K-edge imaging
WO2010120368A2 (en) 2009-04-15 2010-10-21 Lantheus Medical Imaging, Inc. Stabilization of radiopharmaceutical compositions using ascorbic acid
WO2011035140A1 (en) 2009-09-18 2011-03-24 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of contrast moieties to the lungs
KR20170033873A (en) 2010-02-08 2017-03-27 랜티우스 메디컬 이메징, 인크. Methods and apparatus for synthesizing imaging agents, and intermediates thereof
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Also Published As

Publication number Publication date
DE69122092D1 (en) 1996-10-17
HU9203086D0 (en) 1992-12-28
HUT69168A (en) 1995-08-28
SG43931A1 (en) 1997-11-14
NO923739D0 (en) 1992-09-25
AU7557891A (en) 1991-10-21
EP0645146A1 (en) 1995-03-29
CA2079212A1 (en) 1991-09-29
US5614168A (en) 1997-03-25
ATE142508T1 (en) 1996-09-15
LV10056B (en) 1995-02-20
GB9006977D0 (en) 1990-05-23
US5458869A (en) 1995-10-17
ES2091323T3 (en) 1996-11-01
WO1991014460A1 (en) 1991-10-03
FI924297A (en) 1992-09-25
LV10056A (en) 1994-05-10
AU645796B2 (en) 1994-01-27
DK0521977T3 (en) 1996-09-30
DE69122092T2 (en) 1997-03-06
FI924297A0 (en) 1992-09-25
JPH06507147A (en) 1994-08-11
EP0521977A1 (en) 1993-01-13
NO923739L (en) 1992-11-06
EP0521977B1 (en) 1996-09-11
HK219596A (en) 1997-01-03
LT3535B (en) 1995-11-27

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Legal Events

Date Code Title Description
TK9A Rectifications: patents

Free format text: NYCOMED IMAGING AS, NYCOVEIEN 2, P.O. BOX 4220 TORSHOV, N-0401 OSLO 4, NO, 19951130

MM9A Lapsed patents

Effective date: 19980602