LTIP332A - Inhalator without propeller gas with foreign air stream - Google Patents

Inhalator without propeller gas with foreign air stream

Info

Publication number
LTIP332A
LTIP332A LTIP332A LTIP332A LTIP332A LT IP332 A LTIP332 A LT IP332A LT IP332 A LTIP332 A LT IP332A LT IP332 A LTIP332 A LT IP332A LT IP332 A LTIP332 A LT IP332A
Authority
LT
Lithuania
Prior art keywords
substance
air stream
dose
inhalator
button
Prior art date
Application number
LTIP332A
Other languages
Lithuanian (lt)
Inventor
Gerhard Poss
Juergen Wittekind
Andreas Kuehnel
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of LTIP332A publication Critical patent/LTIP332A/en
Publication of LT3125B publication Critical patent/LT3125B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0096Hindering inhalation before activation of the dispenser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • A61M2205/071General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicinal Preparation (AREA)
  • Lasers (AREA)
  • External Artificial Organs (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Sorption Type Refrigeration Machines (AREA)
  • Feeding And Controlling Fuel (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treating Waste Gases (AREA)
  • Engine Equipment That Uses Special Cycles (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Nozzles (AREA)

Abstract

The invention relates to a propellant-free inhaler which has a storage chamber (6) for a powdered substance to be inhaled, which is associated with a metering device (8), which is manually operated by means of a button, having a metering chamber (7) for receiving a given dose of the powdered substance. The device also has a lateral mouth piece (11) for active breathing in, with an air channel (7) for distributing the particular dose of the powdered substance in the air stream. To ensure that the dosage provided is highly reproducible, a high proportion of this dose leaves the inhaler and the medicinal substance is reproducibly dispersed, a trigger operated pump (12,19,20) is provided which can be manually primed before the inhalation process by means of a button (1,42) and which can be actuated in synchronism with the breathing, thereby generating a current of foreign air which disperses the metered substance.
LTIP332A 1990-08-30 1993-02-09 Inhalator without propeller gas with foreign air stream LT3125B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4027391A DE4027391A1 (en) 1990-08-30 1990-08-30 GAS-FREE INHALATION DEVICE
PCT/EP1991/001593 WO1992004068A1 (en) 1990-08-30 1991-08-22 Inhalator without propeller gas with foreign air stream

Publications (2)

Publication Number Publication Date
LTIP332A true LTIP332A (en) 1994-08-25
LT3125B LT3125B (en) 1994-12-27

Family

ID=6413200

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP332A LT3125B (en) 1990-08-30 1993-02-09 Inhalator without propeller gas with foreign air stream

Country Status (26)

Country Link
US (1) US5617845A (en)
EP (1) EP0549605B1 (en)
JP (1) JP2505339B2 (en)
KR (1) KR0179376B1 (en)
AT (1) ATE116558T1 (en)
AU (1) AU654499B2 (en)
CA (1) CA2090227C (en)
CZ (1) CZ281264B6 (en)
DE (2) DE4027391A1 (en)
DK (1) DK0549605T3 (en)
EE (1) EE03092B1 (en)
ES (1) ES2066463T3 (en)
FI (1) FI105078B (en)
GR (1) GR3015540T3 (en)
HU (1) HU213661B (en)
IE (1) IE71162B1 (en)
IL (1) IL99285A (en)
LT (1) LT3125B (en)
LV (1) LV10398B (en)
NO (1) NO304353B1 (en)
NZ (1) NZ239530A (en)
PL (1) PL166852B1 (en)
RU (1) RU2098144C1 (en)
SK (1) SK278886B6 (en)
WO (1) WO1992004068A1 (en)
ZA (1) ZA916741B (en)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990013327A1 (en) * 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
DE4133274A1 (en) * 1991-08-22 1993-02-25 Boehringer Ingelheim Kg Device for inhaling medicament - has internal mechanism actuated by breathing of user to mix powder with air
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
JPH06509958A (en) * 1991-08-26 1994-11-10 ミネソタ マイニング アンド マニュファクチャリング カンパニー powder dispenser
US6029661A (en) * 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
WO1993018812A1 (en) * 1992-03-25 1993-09-30 Tebro S.A. Powder jet dispenser for medicament inhalation therapies
ES2092727T3 (en) * 1992-06-05 1996-12-01 Hoechst Ag INHALER.
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
WO1994011044A2 (en) * 1992-11-12 1994-05-26 Minnesota Mining And Manufacturing Company Powder inhaler
FR2700279B1 (en) * 1993-01-14 1995-03-17 Valois Portable device for projecting doses of a fluid substance using a stream of compressed air.
FR2701653B1 (en) * 1993-02-18 1995-04-07 Valois Dosing device for the inhalation of dry powder.
DE4319514C2 (en) * 1993-06-14 2003-06-18 Sofotec Gmbh & Co Kg powder inhaler
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
FR2718968B1 (en) * 1994-04-20 1996-07-26 Valois Sa Insert delimiting a metering chamber of an inhaler.
FI95441C (en) * 1994-05-31 1996-02-12 Leiras Oy Inhaler drug chamber
PL182198B1 (en) * 1995-06-21 2001-11-30 Asta Medica Ag Pharmaceutic powder holding container with integrated measuring device and powdered
DE19522415C2 (en) * 1995-06-21 2003-12-04 Sofotec Gmbh & Co Kg Drug powder cartridge with integrated dosing device and powder inhaler with means for actuating the dosing device of the drug powder cartridge
JP3317823B2 (en) * 1995-08-11 2002-08-26 株式会社ユニシアジェックス Dosing device
FR2738153B1 (en) * 1995-09-04 1998-01-02 Valois INHALATION APPARATUS FOR DELIVERING PRECISE AND REPRODUCIBLE DOSES OF POWDERY PRODUCT
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
SE9700936D0 (en) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
SE9700937D0 (en) 1997-03-14 1997-03-14 Astra Ab Powder inhales I
SE9700935D0 (en) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
GB9719093D0 (en) 1997-09-10 1997-11-12 Ml Lab Plc Improvements to dry powder inhalers
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
DE19825434C2 (en) * 1998-01-30 2002-03-28 Ig Spruehtechnik Gmbh Inhaler for powdered medication
PL188188B1 (en) 1998-01-30 2004-12-31 Hagepharm Gmbh Inhaling device for administering powdered drugs
US6223746B1 (en) * 1998-02-12 2001-05-01 Iep Pharmaceutical Devices Inc. Metered dose inhaler pump
US6655379B2 (en) 1998-03-16 2003-12-02 Nektar Therapeutics Aerosolized active agent delivery
US6260549B1 (en) 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
PT1089783E (en) 1998-06-22 2005-01-31 Astrazeneca Ab DEVICE FOR EMPTYING CAVITIES CONTAINING PO
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
FI990915A0 (en) * 1999-04-23 1999-04-23 Orion Yhtymae Oyj powder inhaler
EP1183061B2 (en) * 1999-06-05 2012-10-17 Innovata Biomed Limited Medicament delivery system
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
ES2165768B1 (en) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa NEW DERIVATIVES OF QUINUCLIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
GB9920839D0 (en) * 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
WO2001087390A2 (en) 2000-05-12 2001-11-22 Iep Pharmaceutical Devices Inc. Powder/liquid metering valve
GB0015043D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
AU2001283546A1 (en) 2000-08-14 2002-02-25 Advanced Inhalation Research, Inc. Inhalation device and method
DE10047722A1 (en) 2000-09-27 2002-04-11 Schuckmann Alfred Von Dosing device that can be activated by the user's suction air flow
US20110301569A1 (en) 2001-01-20 2011-12-08 Gordon Wayne Dyer Methods and apparatus for the CVCS
JP5154732B2 (en) * 2001-02-06 2013-02-27 イノバータ・バイオメッド・リミテッド Drug
US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
FI20011317A0 (en) * 2001-06-20 2001-06-20 Orion Corp The powder inhaler
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10144572B4 (en) * 2001-09-11 2013-08-01 Sanofi Sa Inhaler for powdery, in particular medicinal substances
DE10165101B3 (en) * 2001-09-11 2014-02-13 Sanofi Sa Inhaler for powdery, in particular, medicinal products comprises a linearly movable dosing chamber whose contents are carried along by a component of the suctioning air stream
DE10165112B3 (en) * 2001-09-11 2013-08-01 Sanofi Sa Inhaler for powdery, in particular, medicinal products comprises a linearly movable dosing chamber whose contents are carried along by a component of the suctioning air stream
GB0128148D0 (en) * 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
US7258118B2 (en) 2002-01-24 2007-08-21 Sofotec Gmbh & Co, Kg Pharmaceutical powder cartridge, and inhaler equipped with same
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
EP1905472A3 (en) 2002-09-16 2008-04-16 von Schuckmann, Alfred Inhaler for powdered, in particular medical, substances
EP1539286B1 (en) 2002-09-16 2015-01-21 Sanofi SA Inhaler for powdery, in particular, medical substances
FR2849386B1 (en) * 2002-12-27 2005-03-18 Bertin Technologies Sa INHALATION DEVICE FOR DRY POWDER
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
GB0407627D0 (en) * 2004-04-02 2004-05-05 Vectura Ltd Corkscrew pump
WO2005102429A1 (en) * 2004-04-21 2005-11-03 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
ES2257152B1 (en) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. COMBINATIONS THAT INCLUDE ANTIMUSCARINIC AGENTS AND BETA-ADRENERGIC AGONISTS.
RS50786B (en) 2004-05-31 2010-08-31 Laboratorios Almirall S.A. Combinations comprising antimuscarinic agents and beta-adrenergic agonists
CN1997418B (en) 2004-07-16 2010-08-11 奥米罗有限公司 Inhaler for the administration of powdered pharmaceuticals, and a powder cartridge system for use with this inhaler
ES2265276B1 (en) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. DERIVATIVES OF 4- (2-AMINO-1-HYDROXYETHYL) Phenol as agonists of the BETA2 ADRENERGIC RECEIVER.
DE102005033397A1 (en) 2005-07-18 2007-01-25 Alfred Von Schuckmann Inhaler for powdery, in particular medicinal substances
GB2433207B (en) 2006-02-21 2009-01-07 Jianhe Li Active suction actuated inhalers with timing devices
DE102006029753A1 (en) 2006-03-10 2007-09-13 Alfred Von Schuckmann Inhaler for powdered substances
GB0614621D0 (en) * 2006-07-24 2006-08-30 3M Innovative Properties Co Metered dose dispensers
DE102006044752A1 (en) * 2006-09-20 2008-04-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Piston
US20100139655A1 (en) * 2006-11-19 2010-06-10 Aespironics Ltd Dry-powder inhaler
MX2009006787A (en) 2006-12-22 2009-07-10 Almirall Lab Inhalation device for drugs in powder form.
ES2306595B1 (en) 2007-02-09 2009-09-11 Laboratorios Almirall S.A. NAPADISYLATE SALT OF 5- (2 - ((6- (2,2-DIFLUORO-2-PHENYLETOXI) HEXIL) AMINO) -1-HYDROXYETHYL) -8-HYDROXYCHINOLIN-2 (1H) -ONE AS ADRENERGIC RECEIVER AGONIST BETA2 .
WO2008101991A1 (en) * 2007-02-21 2008-08-28 Novo Nordisk A/S Breath actuation mechanism for an aerosol generating device
ES2320955B1 (en) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. NEW DERIVATIVES OF 3 - ((1,2,4) TRIAZOLO (4,3-A) PIRIDIN-7-IL) BENZAMIDA.
US8496002B2 (en) * 2007-06-12 2013-07-30 Civitas Therapeutics, Inc. Powder inhaler devices
EP2042208A1 (en) * 2007-09-25 2009-04-01 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
DE102007053590A1 (en) * 2007-11-09 2009-05-14 Astra Zeneca Ab Hand-held device for inhaling substances
DE102007056263A1 (en) * 2007-11-22 2009-05-28 Siegfried Generics International Ag Dosing device for inhaling a powdery substance
ES2320961B1 (en) 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. DERIVATIVES OF 4- (2-AMINO-1-HYDROXYETHYL) PHENOL AS BETA2 ADRENERGIC RECEIVER AGONISTS.
CA2706018C (en) 2007-11-30 2015-11-24 Boehringer Ingelheim International Gmbh 1, 5-dihydro-pyrazolo [3,4-d]pyrimidin-4-one derivatives and their use as pde9a modulators for the treatment of cns disorders
DK2230934T3 (en) 2007-12-14 2012-11-26 Aerodesigns Inc Release of aerosolizable food products
EP2096105A1 (en) * 2008-02-28 2009-09-02 Laboratorios Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
UA105362C2 (en) 2008-04-02 2014-05-12 Бьорингер Ингельхайм Интернациональ Гмбх 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
EP2108641A1 (en) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
WO2010008523A1 (en) * 2008-07-13 2010-01-21 Map Pharmaceuticals, Inc. Methods and apparatus for delivering aerosolized medication
PE20110383A1 (en) 2008-09-08 2011-07-15 Boehringer Ingelheim Int PYRAZOLOPYRIMIDINONES AS INHIBITORS OF PHOSPHODIESTERASE 9A (PDE9A)
US8109414B2 (en) * 2008-10-07 2012-02-07 Ing. Erich Pfeiffer Gmbh Discharge device
EP2196465A1 (en) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
UY32297A (en) 2008-12-22 2010-05-31 Almirall Sa MESILATE SALT OF 5- (2 - {[6- (2,2-DIFLUORO-2-PHENYLITOXI) HEXIL] AMINO} -1-HYDROXYETHYL) -8-HYDROXYCHINOLIN-2 (1H) -ONA AS A RECEIVER AGONIST B (BETA ) 2 ACRENERGIC
EP2201977A1 (en) * 2008-12-23 2010-06-30 Siegfried Generics International AG Metering device for creating a gas flow with an active agent
EP2221055A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function
EP2221297A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases
EP2226323A1 (en) 2009-02-27 2010-09-08 Almirall, S.A. New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives
EP2228368A1 (en) 2009-03-12 2010-09-15 Almirall, S.A. Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
EP2414363B1 (en) 2009-03-31 2014-01-08 Boehringer Ingelheim International GmbH 1-heterocyclyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one derivatives and their use as pde9a modulators
EP2322176A1 (en) 2009-11-11 2011-05-18 Almirall, S.A. New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives
EP2380890A1 (en) 2010-04-23 2011-10-26 Almirall, S.A. New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors
EP2386555A1 (en) 2010-05-13 2011-11-16 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities
EP2394998A1 (en) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
DK2603511T3 (en) 2010-08-12 2017-05-08 Boehringer Ingelheim Int 6-CYCLOALKYL-1, 5-DIHYDRO-PYRAZOLO- [3,4-D] PYRIMIDIN-4-ON DERIVATIVES AND THEIR USES AS PDE9A INHIBITORS
RU2561570C2 (en) * 2010-09-06 2015-08-27 Кьези Фармасьютичи С.П.А. Actuating mechanism of dosing inhaler and dosing inhaler
EP2441755A1 (en) 2010-09-30 2012-04-18 Almirall, S.A. Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
EP2463289A1 (en) 2010-11-26 2012-06-13 Almirall, S.A. Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors
US8809345B2 (en) 2011-02-15 2014-08-19 Boehringer Ingelheim International Gmbh 6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders
EP2489663A1 (en) 2011-02-16 2012-08-22 Almirall, S.A. Compounds as syk kinase inhibitors
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
EP2518071A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Imidazopyridine derivatives as PI3K inhibitors
EP2518070A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Pyrrolotriazinone derivatives as PI3K inhibitors
EP2527344A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases
EP2526945A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. New CRTH2 Antagonists
EP2548876A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists
EP2548863A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists.
EP2554544A1 (en) 2011-08-01 2013-02-06 Almirall, S.A. Pyridin-2(1h)-one derivatives as jak inhibitors
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2592078A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
EP2592077A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
EP2647627A1 (en) 2012-04-02 2013-10-09 Almirall, S.A. Salts of 5-[(1r)-2-({2-[4-(2,2-difluoro-2-phenylethoxy)phenyl] ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1h)-one.
EP2666465A1 (en) 2012-05-25 2013-11-27 Almirall, S.A. Novel dosage and formulation
EP2668941A1 (en) 2012-05-31 2013-12-04 Almirall, S.A. Novel dosage form and formulation of abediterol
US20150202392A1 (en) * 2012-07-20 2015-07-23 Sanofi Sa Metering element for an inhalation device and inhalation device comprising a metering element
WO2014060431A1 (en) 2012-10-16 2014-04-24 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
EP2738172A1 (en) 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
BR112015013628A2 (en) 2012-12-18 2017-07-11 Almirall Sa cyclohexyl and quinuclidinyl carbamate derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities
AR094797A1 (en) 2013-02-15 2015-08-26 Almirall Sa PIRROLOTRIAZINE DERIVATIVES AS PI3K INHIBITORS
AR095222A1 (en) * 2013-04-03 2015-09-30 Sanofi Sa MEASUREMENT ELEMENT FOR AN INHALATION AND ASSEMBLY DEVICE FOR AN INHALATION DEVICE INCLUDING A MEASUREMENT ELEMENT
EP2848615A1 (en) 2013-07-03 2015-03-18 Almirall, S.A. New pyrazole derivatives as CRAC channel modulators
WO2015091285A1 (en) 2013-12-19 2015-06-25 Almirall S.A. Dosage formulation comprising salmeterol and fluticasone propionate
US10610651B2 (en) * 2014-06-09 2020-04-07 Aerami Therapeutics, Inc. Self-puncturing liquid drug cartridges and associated dispenser
MA41938A (en) 2015-04-21 2018-02-28 Almirall Sa AMINO-SUBSTITUTED HETEROCYCLIC DERIVATIVES USED AS SODIUM CHANNEL INHIBITORS
WO2016202800A1 (en) 2015-06-16 2016-12-22 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
WO2017076990A1 (en) 2015-11-05 2017-05-11 Almirall, S.A. Addition salts of n-[4-(4-{[(1s)-1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-1h-indol-6-yl]sulfamide
TW201919682A (en) 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 Novel compounds activating the Nrf2 pathway
CN109172978B (en) * 2018-10-17 2024-07-02 河南省人民医院 Intelligent adjustable one-way exhaust device
EP3693044A1 (en) * 2019-02-07 2020-08-12 Koninklijke Philips N.V. Breath actuated inhalers
WO2020148633A1 (en) * 2019-01-14 2020-07-23 Philip Morris Products S.A. Dry powder inhaler
WO2024015888A1 (en) * 2022-07-14 2024-01-18 Boston Scientific Scimed, Inc. Valve assembly for a device for delivering agents

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US2829642A (en) * 1954-10-18 1958-04-08 Melfy Frank A De Nebulizer having means for eliminating failures
US2992645A (en) * 1958-05-06 1961-07-18 Benger Lab Ltd Disperser for powders
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
US3900138A (en) * 1972-08-07 1975-08-19 Minnesota Mining & Mfg Medicament dispenser
FR2224175B1 (en) * 1973-04-04 1978-04-14 Isf Spa
GB1479283A (en) * 1973-07-23 1977-07-13 Bespak Industries Ltd Inhaler for powdered medicament
US4014336A (en) * 1975-01-13 1977-03-29 Syntex Puerto Rico, Inc. Inhalation device
FR2299011A1 (en) * 1975-01-29 1976-08-27 Obert Jean Claude PART AEROSOL GENERATOR
SE411705B (en) * 1976-11-09 1980-02-04 Draco Ab DEVICE FOR GENERATION OF A SHIELD, ESSENTIAL FUEL-FREE AEROSOL
DE2726934A1 (en) * 1977-06-15 1979-01-04 Wokoeck Hans Dieter Automatic snuff mixer and dispenser - has motor driven vibrator and dispenser and pump operated ejector with indicator devices
US4274403A (en) * 1979-08-29 1981-06-23 Struve Roger L Inhaler
DE3040641A1 (en) * 1980-10-29 1982-05-27 C.H. Boehringer Sohn, 6507 Ingelheim Mouthpiece for aerosol inhalation - with flat and slider for actuation by inspiration
SE438261B (en) * 1981-07-08 1985-04-15 Draco Ab USE IN A DOSHALATOR OF A PERFORED MEMBRANE
FR2516387A1 (en) * 1981-11-16 1983-05-20 Fabre Sa Pierre Medical nasal inhaler for volatile constituents in microcapsules - which are in dose batches evenly spaced along flexible backing strip
US4570630A (en) * 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
FI69963C (en) * 1984-10-04 1986-09-12 Orion Yhtymae Oy DOSERINGSANORDNING
US4803978A (en) * 1985-08-09 1989-02-14 Johnson Iv John J Apparatus for actuating an inhaler
FR2598918B1 (en) * 1986-05-23 1988-08-05 Lille Ii Universite Droit Sant DEVICE FOR THE INSUFFLATION IN THE RESPIRATORY TRACT OF A RADIOOPAQUE POWDER IN THE FINELY DIVIDED STATE
GB8804069D0 (en) * 1988-02-22 1988-03-23 Britains Petite Ltd Dispensers for powdered medication
ATE104867T1 (en) * 1988-10-04 1994-05-15 Univ Johns Hopkins INHALATION DEVICE FOR AEROSOLS.
DK479189D0 (en) * 1989-01-06 1989-09-28 Hans Gernot Schenk INHALER
IT1230313B (en) * 1989-07-07 1991-10-18 Somova Spa INHALER FOR CAPSULES MEDICATIONS.

Also Published As

Publication number Publication date
CZ281264B6 (en) 1996-07-17
KR930702037A (en) 1993-09-08
ES2066463T3 (en) 1995-03-01
SK278886B6 (en) 1998-04-08
LV10398B (en) 1996-06-20
EE03092B1 (en) 1998-06-15
HUT66984A (en) 1995-01-30
HU213661B (en) 1997-09-29
DE4027391A1 (en) 1992-03-12
US5617845A (en) 1997-04-08
JPH06500242A (en) 1994-01-13
CA2090227C (en) 2004-11-30
NO930707L (en) 1993-02-26
FI930845A0 (en) 1993-02-25
FI105078B (en) 2000-06-15
PL166852B1 (en) 1995-06-30
IL99285A (en) 1995-12-31
EP0549605A1 (en) 1993-07-07
IE71162B1 (en) 1997-01-29
GR3015540T3 (en) 1995-06-30
AU654499B2 (en) 1994-11-10
CZ27893A3 (en) 1993-07-14
KR0179376B1 (en) 1999-04-01
ZA916741B (en) 1992-05-27
AU8339891A (en) 1992-03-30
HU9300558D0 (en) 1993-06-28
LT3125B (en) 1994-12-27
SK13193A3 (en) 1993-07-07
ATE116558T1 (en) 1995-01-15
NO304353B1 (en) 1998-12-07
DE59104168D1 (en) 1995-02-16
EP0549605B1 (en) 1995-01-04
IE913052A1 (en) 1992-03-11
JP2505339B2 (en) 1996-06-05
FI930845A (en) 1993-02-25
WO1992004068A1 (en) 1992-03-19
LV10398A (en) 1995-02-20
DK0549605T3 (en) 1995-03-13
RU2098144C1 (en) 1997-12-10
NZ239530A (en) 1994-12-22
NO930707D0 (en) 1993-02-26
CA2090227A1 (en) 1992-03-01

Similar Documents

Publication Publication Date Title
GR3015540T3 (en) Inhalator without propeller gas with foreign air stream.
CZ80395A3 (en) Pharmaceutical preparation
HU9301590D0 (en) Inhaler not using driving gas
KR0179378B1 (en) Powder inhaler
CA2090224A1 (en) Inhalation device without propellant gas
ES252912U (en) Inhalation device.
ES444241A1 (en) Inhalation device
DE69322789D1 (en) DRY POWDER INHALATOR
ES444239A1 (en) Inhalation device
FR2352556A1 (en) Nasal and oral powder inhaler for medicines etc. - uses cyclone chamber to entrain powder into air stream
NZ329747A (en) Method of respiratory delivery of insulin as a dry powder

Legal Events

Date Code Title Description
MK9A Expiry of a patent

Effective date: 20130209