LT6342B - Blood vessel inner wall ultrasound cleaning device - Google Patents

Abstract

The invention is related to medical devices and can be used for cleaning inner walls of blood vessels and suction. In order to increase internal blood vessel walls cleaning efficiency by expanding functional scope of blood vessel inner wall ultrasound cleaning device (1) (local dosage of drugs and removal of plaque by suction), ultrasound waveguide (2) of the device (1), having a spiral-shaped part (3) further comprises a spring (5) with an attached sphere (4', 4''), which form a closed space (9) together with windings (8) of the spiral-shaped part (3), wherein vacuum is created and nanoparticles are stored. The waveguide (2) is attached to the ultrasound vibrations generator (6) which induce deformations in the spiral-shaped part (3) of the waveguide (2) for generating stream of cavitation (7). Suction of plaque into the ultrasound cleaning device (1) is done in the closed space (9) between windings (8) of the spiral forming vacuum and inducing deformations in the waveguide (2) from counter direction running wave.

Description

Field of the Invention

The invention relates to the medical field and can be used for the medical cleaning of the inner walls of blood vessels and for the suction of plaque on the surface of the walls.

State of the art

Pat. LT5248 B discloses an ultrasonic catheter consisting of an ultrasonic source consisting of a high frequency oscillator with a piezo-transducer, a consistently connected mechanical vibration concentrator, a metal wire waveguide, wherein the free end of the metal wire waveguide is a helical material made of a single and high elastic material, such as stainless steel, nickel, titanium or their alloys.

In the given ultrasound catheter, the tip of the metal wire probe is loose, leading to potential spiral fracture at certain frequencies of the spiral, and the drug and contrast media supplied by the catheter increase the likelihood of overdose, complicating the process of invasive therapy and reducing reliability.

Pat. LT 5533 B discloses an ultrasonic micropump dispenser for supplying and dispensing fluids consisting of a cylindrical housing containing a conical helical element and a vibration excitation generator, e.g. the piezo-ceramic ring is mounted on the cylindrical body. The inside of the cylindrical body is filled with liquid.

In the specified device, the dosing-pumping fluid cannot be accurately routed through the catheter to a local therapy site in the blood vessel, since the entire catheter must be filled with dosing fluid and the source of oscillation is external, which results in low efficiency.

In European patent application no. 08478001.4 discloses the closest analogue: an ultrasonic device for internal vascular cleaning, consisting of a special-shaped waveguide with a free end wound in a helix. The waveguide is excited from a high-frequency oscillator.

The device referred to may accommodate the dosing liquid (drugs) at the end of the waveguide helix only in the form of a frozen capsule or a powder mixed with an adhesive ointment which, when excited by ultrasound generator oscillations, passes through the waveguide into The suction of the generated waste into the catheter is done through an external suction device.

The novel ultrasonic intraocular cleansing device of the present invention overcomes the drawbacks of the aforementioned devices and enhances the efficiency of vascular cleaning and expands the functional capabilities of the device (topical drug delivery and plaque suction).

Brief description of the drawings

The invention is explained in the figures:

FIG. 1. a cross-sectional view of the ultrasonic waveguide;

FIG. 2a is a representation of the ultrasonic waveguide in a curved position;

FIG. 2b shows an ultrasonic waveguide in a curved opposite position.

Brief Description of the Invention

The object of the invention, to increase the efficiency of vascular cleaning by expanding the functional capabilities of the ultrasound internal vascular cleaning device (topical drug dosage and plaque suction), is achieved by forming the ultrasonic waveguide of the vascular cleaning device with a variable cross sectional wire This forms a closed cavity into which drug delivery nanosystems, such as nanoparticles, nanospheres, nanocapsules and hydrogels, can be placed. Vacuuming of the resulting waste into the catheter is accomplished by creating a vacuum in the closed cavity between the helix turns and causing deformation of the traveling wave in the opposite direction in the waveguide.

DETAILED DESCRIPTION OF THE INVENTION The vascular cleaning device (1) shown in the figure comprises an ultrasonic waveguide (2) having a helical working part (3), which is bounded on both sides by a spring (5) connected by spheres (4 ', 4 "). drug delivery nanosystems (not shown), such as nanoparticles, nanospheres, nanocapsules, or hydrogels. Said waveguide (2) is connected to an ultrasonic oscillator (6).

Fig. 4a shows a vascular cleaning device comprising an ultrasonic waveguide (2) with a helical working part (3), bounded on both sides by spheres (4 ', 4 ") connected by a spring (5) and containing inside drug delivery nanosystems. (not shown in the drawing) such as nanoparticles, nanospheres, nanocapsules, and hydrogels. The waveguide (2) connected to the ultrasonic oscillator (6), in the helical working part (3), is induced by bending deformations causing the formation of cavitation flows (7).

The operation of an ultrasound internal vascular purifier (1) is described below.

The high-frequency mechanical oscillations from the ultrasonic generator (6) are transmitted to the waveguide (2) where they propagate along its entire length to the helical working part (3). The waveguide workpiece (3), thanks to its construction, allows a certain amount of drugs to be placed in it, in the form of nanoparticles (drug delivery nanosystems), which allows precise delivery of the drugs to the defined (lesion) site.

With the internal vascular cleanser (1) running, the mechanical work of the workpiece (3), the elevated temperature, and the hydrodynamic processes in the blood accelerate the distribution of nanoparticulate drugs in the working field (site of injury). The nanoparticles dispersed in the liquid are exposed to concentrated energy through the waveguide (2) and its helical working part (3) with spheres (4 ', 4'), i.e. cavitation processes are induced in the bloodstream. The cavitation process is distributed over the entire length of the workpiece (3) in the radial direction (7). During the cavitation process, microbubbles are formed in the fluid (i.e., blood), the burst of which micro-energy destroys the plaque on the inner walls of the vessel and destroys (removes) the blockage of the vessel. Upon excitation in the waveguide (2) and also in the working part (3), bending deformations in the opposite direction are performed by suctioning the generated waste into the catheter (not shown) through a closed cavity (9) between the spiral windings (8) and spheres (4 ', 4 "). ) vacuum.

Compared to its closest counterpart, this new ultrasound internal vascular cleanser with drug delivery nanosystems helps to reduce the cavitation threshold (the amount of energy to cause cavitation), shreds and dissolves blood vessel thrombus, promotes tissue regeneration, reduces the risk of drug overdose, and increases the reliability and effectiveness of vascular cleansing.

Claims (2)

1. An ultrasound internal vascular cleaning device (1), comprising a special shape of a waveguide (2), the free end of which is wound in a spiral, characterized in that the inner space (9) of the working part (3) of the waveguide (2) is additionally limited by two spheres (4 ', 4 ") connected by a spring (5) to form a closed cavity (9) bounded by windings (8) of said spiral-shaped working part (3) and said spheres (4', 4"). Ultrasonic intra-vascular cleaning device (1) according to claim 1, characterized in that a vacuum is created in the closed cavity (9) of the working part (3) of the waveguide (2) when the device (1) is operating.