LT6087B - Device and method for ultrasonic transmission to biological tissues - Google Patents

Abstract

Invention related with medical technicians, specifically for devices with complex therapeutic @effect to biological tissues or fragmented structures. The device for ultrasonic transmission to biological tissues, consisting of acoustic radiation source located on the rods, which are tightly connected to the rod position locker and bulk under it fixed with contact bars. Contact bars resting along the body and the acoustic source control block. Control block has the toroidal shape of the ring -shaped cuff which is mounted on the outer nozzle is connected via a tube to the water supply pump and the outer side of the toroidal cuff axis perpendicular to attach at least two acoustic sources. Acoustic sources of external connected to a programmable ultrasonic generator and the internal toroidal cuff portion is in contact with the human skin surface to suppress the interior of the fluid with pressure. Method of ultrasonic transition to tissues biological of human using effect of ultrasonic on the human angiography performed.

Description

BACKGROUND OF THE INVENTION The present invention relates to medical technology, particularly devices having complex therapeutic effects on biological tissues or their fragmentary structures under the influence of temperature, magnetic field, oscillations, which may be used to correct some systemic vascular pathologies or pathological conditions: fresh and old thrombus lysis, thromboembolic destruction of atherosclerotic derivatives of various origins and structures, and recanalization of blood vessels, increasing the local penetration of medicinal drugs into tissues in order to maximize therapeutic effect and prevent side effects (toxic) of drugs.

There is a known mode of human ultrasound exposure (see RU Patent No. 2110247, A 61 H 23/02), but it is not possible to apply ultrasound to a specifically selected site of the human body to increase the effectiveness of the ultrasound by destroying and at the same time and structure atherosclerotic derivatives in all layers of the vascular wall proliferated by lipidocalcifications: intimate, media, adventitial, while restoring the elasticity of the vascular wall.

There is a known mode of human exposure to ultrasound using contact mechanical elements which act directly on certain human tissues (see DE patent application 2713438, A 61 H 23/02 and DE patent application 3719331, A 61 H 23/02 ), however, it does not provide effective lysis of fresh and old thrombi, destruction of thromboembolic and atherosclerotic lesions of various origins and structures to achieve rapid, safe and effective vascular recanalization, as well as the desired (controlled) increase in local drug penetration into selected tissues until an effective therapeutic concentration is obtained, thus avoiding systemic toxic effects.

There is also known a method of acoustic therapy (see RU patent 2145206, A 61 H 23/02, 10.02.2000), the action of which on the human body is based on its presence in a liquid, e.g. in a bath in which acoustic oscillations are excited through the liquid as a vector in the frequency range of 1000-6000 Hz. The disadvantage of the method described is that the effect obtained by using it is systemic, i.e. j the whole organism, which is often unsafe and optimal, is not able to be exposed to a specific site of the human body.

There is a known device (see U.S. Patent No. 4,779,615, A 61 H 23/00), which is based on direct human contact with only the surface of the human body, i.e. skin. In this case, it is not possible to influence the internal structures and organs of the human body, i.e. the very limited therapeutic potential of this technique. Moreover, this method is totally inappropriate for the realization of our goals and technical solution, i.e. efficiently perform lysis of fresh and old thrombi, destruction of thromboembolic and atherosclerotic derivatives of various origins and structures to achieve rapid, safe and effective vascular recanalization, as well as to enhance the desired (controlled) local penetration of drug therapies to obtain effective therapeutic concentrations , thus avoiding systemic toxic effects. The latter may be adopted as a prototype.

The object of the present invention is to increase the efficiency of vascular cleansing by ultrasound exposure to specifically selected areas of human tissue, in particular case vascular wall structures.

SUMMARY OF THE INVENTION The object of the present invention is achieved by transmitting ultrasound to biological tissues by providing an apparatus consisting of an acoustic radiation source located on rods which are firmly connected to a rod positioner and a bar mounted thereon with contact rods resting on the human body. consisting of at least two opposed acoustic sources fixed on the upper part of a toroidal cuff made of a material with good acoustic properties (for example, latex) and connected via a connecting tube to a water pump to apply pressure within the cuff , not exceeding 50% of the upper limit of the patient's blood pressure value, and the inner part of the cuff contacts the surface of the human body (e.g., the skin of the human arm) throughout the perimeter and the ointment with good acoustic properties (e.g. ecologically produced gels used for echoscopy).

The device employs the following method of ultrasound delivery to the human internal organs: using autopsy fragments of human pathologically altered blood vessels (Langendorf's technique), thrombolytic drug is injected into the thrombus occluded or significantly sclerosed (> 80-90%), and 18-100 kHz voltage and thus optimizes the thrombolytic effect of the drug. In the second stage, similarly to the first stage, only pathologically altered areas of human peripheral blood vessels are detected in vivo, drug thrombolytic agent is injected into them, and a voltage of 18-100 kHz is applied from a programmable ultrasound generator and trimerization is performed.

BRIEF DESCRIPTION OF THE DRAWINGS The invention is explained in the figure, which shows an overall view of the construction of a device for ultrasound transfer to biological tissues.

Device for transmitting ultrasound to biological tissues, consisting of a toroidal annular cuff 1 with an outer nozzle 3 mounted via a tube 4 to a water supply pump 5. Acoustic sources 6 with ultrasound mounted perpendicular to the axis of the toroidal cuff the emitting surfaces 7 are located inside the toroidal cuff 1 and the acoustic sources 6 are connected externally to the programmable ultrasonic generator 8.

The device for transmitting ultrasound to biological tissues operates as follows:

Human vascular angiography (one way to diagnose vascular and circulatory conditions) identifies vascular sites requiring ultrasound trobolysis. Thereafter, special medications are applied to these thrombolized blood vessels and a toroidal cuff 1 is applied to the surface of the skin by applying an ointment, which is supplied with a fluid pump through a nozzle 3 on the inner side of the toroidal cuff 2 via a tube 4 does not exceed 50% of the patient's upper blood pressure to allow sufficient contact between the skin surface and the inside of the toroidal cuff. The acoustic sources 6 placed opposite each other from a programmable ultrasonic generator 8 with a voltage of 18-100kHz and the surfaces of internal acoustic sources 7 inside the toroidal cuff begin to emit ultrasonic waves which, through the fluid, transmit to the affected blood vessels of the required organ mediates active determinate thrombolysis and thus removes thromboembolism and thrombolysis products.

Compared to the prototype, the new set of structural elements, thanks to the created acoustic-ultrasonic process, makes it easier and more effective to remove thromboembolism formed in the inner walls of the blood vessels in combination with the administered drugs.

Claims (5)

1. An apparatus for transmitting ultrasound to biological tissues, consisting of an acoustic radiation source located on rods which are firmly connected to a rod positioner and a bar mounted below it, with contact rods resting on the human body and an acoustic source control unit, characterized in that a ring-shaped cuff with an external nozzle connected via a tube with a water supply pump and at least two acoustic sources mounted externally to the programmable ultrasonic generator on the outside of the toroidal cuff perpendicular to the axis of the toroidal cuff, and the inner part of the toroidal cuff contacts by applying a fluid under pressure to the surface. Device for transmitting ultrasound to biological tissues according to claim 1, characterized in that the ultrasound emitting surfaces of the acoustic radiation sources are filled with a fluid inside the toroidal cuff. Device for transmitting ultrasound to biological tissues according to claim 1, characterized in that the inner part of the fluid filled toroidal cuff has a segmental shape in cross-section. Device for transmitting ultrasound to biological tissues according to claims 1-3, characterized in that acoustic sources are supplied with a variable voltage of 18-100kHz from a programmable ultrasonic generator according to a given algorithm. 5. The method of transmitting ultrasound to human biological tissues by means of ultrasound, which involves performing human angiography, identifying the areas of human organs where lysis of blood vessels is required, or vascular wall therapy by ultrasound, and then injecting special drugs into the damaged blood vessels and applying a toroidal cuff to the surface of the skin, lubricating it, which, through a nozzle on the inner side of the toroidal cuff, supplies a fluid pump at a pressure not exceeding 50% of the patient's upper blood pressure to provide sufficient contact between the skin surface and the inner part of the toroidal cuff, and then excite ultrasonic acoustic vibrations by an algorithm that allows the maximum acoustic pressure to be maintained in a determined area of the human organ or tissue.