LT2300033T - Kolageno peptido konjugatai ir jų panaudojimas - Google Patents

Kolageno peptido konjugatai ir jų panaudojimas

Info

Publication number
LT2300033T
LT2300033T LTEP09747654.3T LT09747654T LT2300033T LT 2300033 T LT2300033 T LT 2300033T LT 09747654 T LT09747654 T LT 09747654T LT 2300033 T LT2300033 T LT 2300033T
Authority
LT
Lithuania
Prior art keywords
collagen peptide
peptide conjugates
uses therefor
therefor
conjugates
Prior art date
Application number
LTEP09747654.3T
Other languages
English (en)
Inventor
Jean A. Chmielewski
Marcos M. Pires
David E. Przybyla
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of LT2300033T publication Critical patent/LT2300033T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6435—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
LTEP09747654.3T 2008-05-15 2009-05-15 Kolageno peptido konjugatai ir jų panaudojimas LT2300033T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5342008P 2008-05-15 2008-05-15
PCT/US2009/044093 WO2009140573A1 (en) 2008-05-15 2009-05-15 Collagen peptide conjugates and uses therefor

Publications (1)

Publication Number Publication Date
LT2300033T true LT2300033T (lt) 2017-01-25

Family

ID=41319069

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP09747654.3T LT2300033T (lt) 2008-05-15 2009-05-15 Kolageno peptido konjugatai ir jų panaudojimas

Country Status (6)

Country Link
US (1) US8575311B2 (lt)
EP (1) EP2300033B1 (lt)
AU (1) AU2009246203A1 (lt)
CA (1) CA2724352A1 (lt)
LT (1) LT2300033T (lt)
WO (1) WO2009140573A1 (lt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012027218A2 (en) 2010-08-27 2012-03-01 Corning Incorporated Peptide-modified surfaces for cell culture
KR101348096B1 (ko) 2012-03-29 2014-01-09 한국과학기술연구원 줄기세포의 연골 분화 유도 활성을 가지는 폴리펩타이드
US9550012B2 (en) 2013-08-05 2017-01-24 University Of Notre Dame Du Lac Tissue scaffolds having bone growth factors
US9526762B1 (en) 2013-08-09 2016-12-27 William Marsh Rice University Multidomain peptides for promoting angiogenesis
CN105316363B (zh) * 2014-07-31 2018-10-09 天津大学 一种用redv多肽修饰的双亲梳型基因载体及制备方法
CN105403708A (zh) * 2015-10-13 2016-03-16 中国科学院烟台海岸带研究所 一种筛选高生物吸收利用度的深海鱼皮胶原多肽的方法
WO2020041407A1 (en) * 2018-08-21 2020-02-27 The Johns Hopkins University Rubbery, compliant, and suturable collagen-based scaffolds for tissue engineering applications
CN111303249B (zh) * 2020-01-02 2020-12-18 兰州大学 一种特异性检测病变胶原蛋白的探针、制备方法及应用
WO2023060218A2 (en) * 2021-10-07 2023-04-13 3Helix, Inc. Biologically active collagen hybridizing peptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8283414B2 (en) * 2004-11-23 2012-10-09 The Johns Hopkins University Compositions comprising modified collagen and uses therefor

Also Published As

Publication number Publication date
US20110081324A1 (en) 2011-04-07
CA2724352A1 (en) 2009-11-19
EP2300033B1 (en) 2016-07-20
EP2300033A1 (en) 2011-03-30
WO2009140573A1 (en) 2009-11-19
AU2009246203A1 (en) 2009-11-19
US8575311B2 (en) 2013-11-05
EP2300033A4 (en) 2012-09-19

Similar Documents

Publication Publication Date Title
HK1250042A1 (zh) 溶酶體靶向肽及其應用
EP2170363A4 (en) TISSUE-SPECIFIC PEPTIDE CONJUGATES AND METHOD
ZA201104497B (en) Peptide therapeutic conjugates and uses thereof
ZA201109324B (en) Multimeric peptide conjugates and uses thereof
EP2288622A4 (en) FACTOR IX MODIFIED POLYPEPTIDES AND USES THEREOF
EP2142572A4 (en) TGFP CAP PEPTIDE AND APPLICATIONS THEREOF
EP2318429A4 (en) PROMININ-1 PEPTIDE FRAGMENTS AND ITS USE
LT2300033T (lt) Kolageno peptido konjugatai ir jų panaudojimas
EP2275440A4 (en) GROWTH FACTOR IMITING PEPTIDES AND THEIR USE
EP2315771A4 (en) GLYCOPEPTIDE CONSTRUCTS AND ITS USE
EP2513137A4 (en) PEPTIDES DERIVED FROM SAPOSINE-A AND USES THEREOF
GB0920981D0 (en) Peptides
IL195525A0 (en) Replikin peptides and uses thereof
ZA201100019B (en) Variant hhip1 protein and methods and uses thereof
EP2285827A4 (en) PEPTIDES AND ITS USE
IL216626A0 (en) Albumin-amyloid peptide conjugates and uses thereof
GB0818065D0 (en) Immunogenic peptides and uses thereof
HK1152717A1 (en) Angiogenic peptide
GB0823550D0 (en) Peptide tag and uses thereof
GB0920987D0 (en) Peptides
GB0617564D0 (en) Peptides and methods
EP2244725A4 (en) NOVEL PEPTIDES AND PROTEIN AND USE THEREOF
IL192800A0 (en) Fgf2-binding peptides and uses thereof
GB0817978D0 (en) Peptides
GB0800502D0 (en) Peptides and their uses