LT2020539A - Antikūnai fotoaktyvių baltymų manipuliavimui - Google Patents

Antikūnai fotoaktyvių baltymų manipuliavimui

Info

Publication number
LT2020539A
LT2020539A LT2020539A LT2020539A LT2020539A LT 2020539 A LT2020539 A LT 2020539A LT 2020539 A LT2020539 A LT 2020539A LT 2020539 A LT2020539 A LT 2020539A LT 2020539 A LT2020539 A LT 2020539A
Authority
LT
Lithuania
Prior art keywords
manipulation
proteins
antibodies
antibody
dmnb
Prior art date
Application number
LT2020539A
Other languages
English (en)
Other versions
LT6905B (lt
Inventor
Saulius KLIMAŠAUSKAS
Rasa RAKAUSKAITĖ
Giedrė URBANAVIČIŪTĖ
Rita LASICKIENĖ
Martynas SIMANAVIČIUS
Aurelija ŽVIRBLIENĖ
Original Assignee
Vilniaus Universitetas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vilniaus Universitetas filed Critical Vilniaus Universitetas
Priority to LT2020539A priority Critical patent/LT6905B/lt
Priority to EP21187460.7A priority patent/EP3943111A1/en
Publication of LT2020539A publication Critical patent/LT2020539A/lt
Publication of LT6905B publication Critical patent/LT6905B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Išradimas apibūdina didelio afiniškumo monokloninį antikūną 12B6, kuris specifiškai sąveikauja su fotolabilia DMNB grupe. Šis antikūnas tinka DMNB grupėms, esančioms baltymų (ir potencialiai kitų biomolekulių) sudėtyje, atpažinti. Antikūno ir unikalios DMNB grupės sąveika leidžia imunoprecipitacijos būdu manipuliuoti fotolabiliomis grupėmis žymėtais baltymais.
LT2020539A 2020-07-24 2020-07-24 Antikūnai fotoaktyvių baltymų manipuliavimui LT6905B (lt)

Priority Applications (2)

Application Number Priority Date Filing Date Title
LT2020539A LT6905B (lt) 2020-07-24 2020-07-24 Antikūnai fotoaktyvių baltymų manipuliavimui
EP21187460.7A EP3943111A1 (en) 2020-07-24 2021-07-23 Antibodies for photoactive protein manipulation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LT2020539A LT6905B (lt) 2020-07-24 2020-07-24 Antikūnai fotoaktyvių baltymų manipuliavimui

Publications (2)

Publication Number Publication Date
LT2020539A true LT2020539A (lt) 2022-01-25
LT6905B LT6905B (lt) 2022-04-25

Family

ID=77300731

Family Applications (1)

Application Number Title Priority Date Filing Date
LT2020539A LT6905B (lt) 2020-07-24 2020-07-24 Antikūnai fotoaktyvių baltymų manipuliavimui

Country Status (2)

Country Link
EP (1) EP3943111A1 (lt)
LT (1) LT6905B (lt)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT6159B (lt) * 2013-07-09 2015-05-25 Vilniaus Universitetas Seleno baltymų (selprot) gavimas

Also Published As

Publication number Publication date
EP3943111A1 (en) 2022-01-26
LT6905B (lt) 2022-04-25

Similar Documents

Publication Publication Date Title
CY1118709T1 (el) Αντιγονικα πεπτιδια του παραγοντα διεγερσης αποικιων των κοκκινοκυτταρων (gm-csf) και αντισωματα για ton gm-csf
PH12018501284A1 (en) Anti-tl1a/anti-tnf-alpha bispecific antigen binding proteins and uses thereof
US20210055304A1 (en) Method for the detection of a binding partner of a multispecific binder
CL2021000942A1 (es) Anticuerpos anti-npr1 y usos relacionados.
MX2019008221A (es) Anticuerpo anti-gpc3.
EA202090247A1 (ru) Антитела против cd166 и их применения
RU2633488C2 (ru) Способ определения свободного связывающего партнера мультиспецифичного связующего
ATE314653T1 (de) Immunoassay für c-reaktives protein
EA201070539A1 (ru) НОВЫЕ АНТИТЕЛА, СПЕЦИФИЧНЫЕ К β-АМИЛОИДНЫМ ПЕПТИДАМ, И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ДИАГНОСТИЧЕСКИХ ИЛИ ЛЕКАРСТВЕННЫХ СРЕДСТВ
EA202190237A1 (ru) Способы уменьшения мешающего влияния мишени лекарственного средства в иммунологическом анализе на антитела к лекарственному средству (ada)
MX2022011951A (es) Anticuerpos de la lectina 15 similar a la inmunoglobulina que se une a acido sialico (siglec15) y usos de los mismos.
MX2022016192A (es) Anticuerpos anti-nectina-4 condicionalmente activos.
CO2021014153A2 (es) Anticuerpo monoclonal que se une específicamente a gitr
LT2020539A (lt) Antikūnai fotoaktyvių baltymų manipuliavimui
RU2017114626A (ru) Антитело, связывающее линейный эпитоп человеческого р53, и его применение в диагностике
US11340234B2 (en) Method for the determination of anti-drug antibodies against an effector function suppressed human or humanized drug antibody
MX2022003465A (es) Anticuerpo monoclonal contra proteína de activación de fibroblasto canino de reacción cruzada con proteína de activación de fibroblasto (fap) de ratón y humana.
WO2023159187A3 (en) Anti-sars-cov2 spike (s) antibodies and uses thereof
MX2022003432A (es) Metodos y composiciones que comprenden un anticuerpo monoclonal antictla4 con proteinas de celulas hospederas reducidas y estabilidad del polisorbato-80 aumentada.
MX2021003407A (es) Cuantificacion de anticuerpos en muestras biologicas.
ATE230418T1 (de) Monoklonaler antikörper gegen das humane mx- protein mxa
MX2021007028A (es) Anticuerpo anti-il-17a y uso del mismo.
MX2022003191A (es) Terapias de combinacion con anticuerpos entpd2 y cd73.
WO2021217140A3 (en) Specificity enhancing reagents for covid-19 antibody testing
PH12019500151A1 (en) Immunofiltration method and immunofiltration device for serum fucose protein assay

Legal Events

Date Code Title Description
BB1A Patent application published

Effective date: 20220125

FG9A Patent granted

Effective date: 20220425