LT2014060A - TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ - Google Patents

TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ

Info

Publication number
LT2014060A
LT2014060A LT2014060A LT2014060A LT2014060A LT 2014060 A LT2014060 A LT 2014060A LT 2014060 A LT2014060 A LT 2014060A LT 2014060 A LT2014060 A LT 2014060A LT 2014060 A LT2014060 A LT 2014060A
Authority
LT
Lithuania
Prior art keywords
glucans
beta
cancer cells
immune system
therapeutic composition
Prior art date
Application number
LT2014060A
Other languages
English (en)
Other versions
LT6145B (lt
Inventor
Saulius GRIGIŠKIS
Artur JAVMEN
Mykolas Mauricas
Vilma Čipinytė
Darius Kacanauskas
Fortunatas Grygas
Julius Vaitoška
Original Assignee
Uab "Biocentras"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab "Biocentras" filed Critical Uab "Biocentras"
Priority to LT2014060A priority Critical patent/LT6145B/lt
Priority to EP14733708.3A priority patent/EP3140413A1/en
Priority to US14/435,227 priority patent/US20160184343A1/en
Priority to PCT/IB2014/061654 priority patent/WO2015159134A1/en
Publication of LT2014060A publication Critical patent/LT2014060A/lt
Publication of LT6145B publication Critical patent/LT6145B/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K13/00—Sugars not otherwise provided for in this class

Abstract

Šis išradimas priskiriamas farmacinių biotechnologijų sričiai. Jame aprašomas organizmo imunostimuliavimas, vėžinių ląstelių ardymo procesų inicijavimas bei metastazių susidarymo prevencija, panaudojant skiritingos molekulinės masės vandenyje tirpių beta-gliukanų kompozicijas. Šiame išradime taip pat aprašytas beta-gliukanų mišiniams gauti panaudojamas specifinis biokatalizatorius, produkuojamas Streptomyces rutgersensis 88.
LT2014060A 2014-04-14 2014-04-14 TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ LT6145B (lt)

Priority Applications (4)

Application Number Priority Date Filing Date Title
LT2014060A LT6145B (lt) 2014-04-14 2014-04-14 TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ
EP14733708.3A EP3140413A1 (en) 2014-04-14 2014-05-23 Therapeutical beta-glucan composition, modulating human immune system and initiating the breakdown of cancerous cells
US14/435,227 US20160184343A1 (en) 2014-04-14 2014-05-23 Therapeutical beta-glucan composition, modulating human immune system and initiating the breakdown of cancerous cells
PCT/IB2014/061654 WO2015159134A1 (en) 2014-04-14 2014-05-23 THERAPEUTICAL β-GLUCAN COMPOSITION, MODULATING HUMAN IMMUNE SYSTEM AND INITIATING THE BREAKDOWN OF CANCEROUS CELLS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LT2014060A LT6145B (lt) 2014-04-14 2014-04-14 TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ

Publications (2)

Publication Number Publication Date
LT2014060A true LT2014060A (lt) 2015-02-25
LT6145B LT6145B (lt) 2015-04-27

Family

ID=51022922

Family Applications (1)

Application Number Title Priority Date Filing Date
LT2014060A LT6145B (lt) 2014-04-14 2014-04-14 TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ

Country Status (4)

Country Link
US (1) US20160184343A1 (lt)
EP (1) EP3140413A1 (lt)
LT (1) LT6145B (lt)
WO (1) WO2015159134A1 (lt)

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810646A (en) 1984-11-28 1989-03-07 Massachusetts Institute Of Technology Glucan compositions and process for preparation thereof
US5622939A (en) 1992-08-21 1997-04-22 Alpha-Beta Technology, Inc. Glucan preparation
WO1992013896A1 (en) 1991-02-01 1992-08-20 Bioglucans, L.P. Soluble glucans
AUPN166195A0 (en) 1995-03-13 1995-04-06 Norvet Research Pty Limited Process for glucan extraction
AUPN398295A0 (en) 1995-07-05 1995-07-27 Carlton And United Breweries Limited Chemical compounds and processes for their production
AU6261999A (en) 1998-09-25 2000-04-17 Collaborative Group, Ltd., The Very high molecular weight beta-glucans
NZ521894A (en) 2001-02-15 2006-08-31 Adeka Corp Products containing beta-glucan
US6660722B2 (en) 2001-11-30 2003-12-09 Laboratoires Goemar S.A. Therapeutical treatments
EP1536820B2 (en) 2002-09-04 2013-10-23 Biopolymer Engineering, Inc. Cancer therapy using whole glucan particles and antibodies
US7018986B2 (en) * 2002-09-20 2006-03-28 Immudyne Use of beta glucans for the treatment of osteoporosis and other diseases of bone resorption
KR100457270B1 (ko) 2003-03-18 2004-11-16 주식회사 엔바이오테크놀러지 효모변이주 아이에스투 유래 수용성 글루칸 올리고머를함유하는 면역활성용 또는 암질환 예방 및 치료용 조성물,및 이의 제조방법
US7070778B2 (en) 2003-10-30 2006-07-04 Laboratoire Goemar Sa Therapeutical combination against cancer
KR20040052608A (ko) 2004-04-14 2004-06-23 주식회사 글루칸 베타-글루칸을 유효성분으로 함유하는 골다공증 예방 및치료용 조성물
US20070059310A1 (en) 2005-05-03 2007-03-15 Karel Steven J Therapeutic combination compositions and methods of using same
US8323644B2 (en) 2006-01-17 2012-12-04 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
GB0611600D0 (en) 2006-06-13 2006-07-19 Itm Fuel Cells Ltd Improvements to membranes
CA2655414C (en) 2006-06-15 2019-04-23 Biopolymer Engineering, Inc. Dba Biothera, Inc. Glucan preparations
US20080167268A1 (en) 2006-09-01 2008-07-10 Jun Yan Particulate beta-glucan compositions for regulating dendritic cells
FR2910322B1 (fr) 2006-12-22 2009-10-30 Mer Soc Par Actions Simplifiee Utilisation d'oligo-b-(1,3)-glucanes modifies pour le traite traitement de maladies du systeme immunitaire, oligo-b-(1,3) glucane-(1,3)-mannose, oligo-b-(1,3)-glucane-(1,3)-mannitol et leurs derives, ...
WO2008130719A1 (en) 2007-04-24 2008-10-30 University Of Louisville Therapeutic beta-glucan combinations
CN101772518A (zh) 2007-06-13 2010-07-07 艾伯塔大学校董事会 高粘度β-葡聚糖产物及制备方法
US20090098619A1 (en) 2007-10-16 2009-04-16 Shiu Nan Chen Method of producing liquid and powered mushroom beta-glucan
GB0809808D0 (en) 2008-05-29 2008-07-09 Med Eq As Composition
GB201020190D0 (en) 2010-11-29 2011-01-12 Biotec Pharmacon Asa Glucans

Also Published As

Publication number Publication date
WO2015159134A1 (en) 2015-10-22
EP3140413A1 (en) 2017-03-15
LT6145B (lt) 2015-04-27
US20160184343A1 (en) 2016-06-30

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Legal Events

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BB1A Patent application published

Effective date: 20150225

FG9A Patent granted

Effective date: 20150427