KR970701784A - 뇌-유도 향신경성 인자(BDNF)를 암호화하는 재조합 아데노비루스(Recombinant Adenoviruses Coding for Brain-Derived Neurotrophic Factor(BDNF)) - Google Patents

뇌-유도 향신경성 인자(BDNF)를 암호화하는 재조합 아데노비루스(Recombinant Adenoviruses Coding for Brain-Derived Neurotrophic Factor(BDNF)) Download PDF

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Publication number
KR970701784A
KR970701784A KR1019960705207A KR19960705207A KR970701784A KR 970701784 A KR970701784 A KR 970701784A KR 1019960705207 A KR1019960705207 A KR 1019960705207A KR 19960705207 A KR19960705207 A KR 19960705207A KR 970701784 A KR970701784 A KR 970701784A
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South Korea
Prior art keywords
adenovirus
bdnf
defective recombinant
dna sequence
adenovirus according
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KR1019960705207A
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English (en)
Korean (ko)
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파스칼 바르뇌
드레르 피아
로앙 프라디에
엠마뉴엘 비그네
미셀 페리코데
Original Assignee
필리쁘 베케르
롱프랑 로라 소시에테 아노님
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Publication of KR970701784A publication Critical patent/KR970701784A/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Psychology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019960705207A 1994-03-18 1995-03-02 뇌-유도 향신경성 인자(BDNF)를 암호화하는 재조합 아데노비루스(Recombinant Adenoviruses Coding for Brain-Derived Neurotrophic Factor(BDNF)) KR970701784A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR94/03191 1994-03-18
FR9403191A FR2717496B1 (fr) 1994-03-18 1994-03-18 Virus recombinants, préparation et utilisation en thérapie génique.
PCT/FR1995/000250 WO1995025804A1 (fr) 1994-03-18 1995-03-02 Adenovirus recombinants codant pour le facteur neurotrophique derive du cerveau (bdnf)

Publications (1)

Publication Number Publication Date
KR970701784A true KR970701784A (ko) 1997-04-12

Family

ID=9461190

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960705207A KR970701784A (ko) 1994-03-18 1995-03-02 뇌-유도 향신경성 인자(BDNF)를 암호화하는 재조합 아데노비루스(Recombinant Adenoviruses Coding for Brain-Derived Neurotrophic Factor(BDNF))

Country Status (12)

Country Link
EP (1) EP0750676A1 (es)
JP (1) JPH09510358A (es)
KR (1) KR970701784A (es)
AU (1) AU703793B2 (es)
CA (1) CA2184200A1 (es)
FI (1) FI963674A (es)
FR (1) FR2717496B1 (es)
IL (1) IL112992A0 (es)
MX (1) MX9603490A (es)
NO (1) NO963559L (es)
WO (1) WO1995025804A1 (es)
ZA (1) ZA952244B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830857A (en) * 1995-07-14 1998-11-03 Amgen Inc. Method of treating epilepsy
FR2753379B1 (fr) * 1996-09-13 1998-10-30 Rhone Poulenc Rorer Sa Methode de traitement de la sclerose laterale amyotrophique
CA2408255A1 (en) * 2000-05-05 2001-11-15 Marie T. Filbin Methods for stimulating nervous system regeneration and repair by regulating arginase 1 and polyamine synthesis
EP3755380A4 (en) * 2018-02-20 2021-12-08 Carmel-Haifa University Economic Corporation Ltd. COMPOSITIONS AND PROCEDURES FOR THE ADMINISTRATION AND EXPRESSION OF SMALL PEPTIDES INHIBITORS AND THEIR USE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2113083A1 (en) * 1991-07-10 1993-01-21 Vivien Wong Methods of treatment of motor neuron diseases using members of the bdnf/nt-3/ngf family of molecules
AU3129793A (en) * 1991-11-08 1993-06-07 General Hospital Corporation, The Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration
FR2688514A1 (fr) * 1992-03-16 1993-09-17 Centre Nat Rech Scient Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
AU4995193A (en) * 1992-08-04 1994-03-03 Regeneron Pharmaceuticals, Inc. Method of enhancing differentiation and survival of neuronal precursor cells
EP0669987B1 (en) * 1992-09-25 2008-08-13 Aventis Pharma S.A. Adenovirus vectors for the transfer of foreign genes into cells of the central nervous system, particularly in brain
FR2704234B1 (fr) * 1993-04-22 1995-07-21 Centre Nat Rech Scient Virus recombinants, preparation et utilisation en therapie genique.

Also Published As

Publication number Publication date
AU703793B2 (en) 1999-04-01
MX9603490A (es) 1997-03-29
EP0750676A1 (fr) 1997-01-02
ZA952244B (en) 1996-01-16
JPH09510358A (ja) 1997-10-21
FR2717496B1 (fr) 1996-04-12
FI963674A0 (fi) 1996-09-17
IL112992A0 (en) 1995-06-29
WO1995025804A1 (fr) 1995-09-28
AU1896295A (en) 1995-10-09
NO963559L (no) 1996-08-26
CA2184200A1 (fr) 1995-09-28
FR2717496A1 (fr) 1995-09-22
FI963674A (fi) 1996-09-17

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