KR970020112A - Method for preparing extract of C. oleracea and antioxidant, free radical scavenging, antimutagenic and anti-aging eye disease preventive agent - Google Patents

Method for preparing extract of C. oleracea and antioxidant, free radical scavenging, antimutagenic and anti-aging eye disease preventive agent Download PDF

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Publication number
KR970020112A
KR970020112A KR1019950036567A KR19950036567A KR970020112A KR 970020112 A KR970020112 A KR 970020112A KR 1019950036567 A KR1019950036567 A KR 1019950036567A KR 19950036567 A KR19950036567 A KR 19950036567A KR 970020112 A KR970020112 A KR 970020112A
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extract
free radical
radical scavenging
antioxidant
eye
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KR1019950036567A
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Korean (ko)
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KR0168721B1 (en
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허문영
최재수
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허문영
최재수
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/302—Foods, ingredients or supplements having a functional effect on health having a modulating effect on age
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

결명자(Cassiae semen)은 초결명자(Cassia obtusifolia L.), 또는 결명(Cassia tora L.)의 종자로서 한방에서 건위, 정장, 이뇨 및 완화제로 쓰이고 동의보감에서는 청간명목(淸肝明目)이라 하여 결명자를 끓인 물로 달여마시면 간에 좋고 나아가 눈을 밝게 한다고 알려져왔다.Cassiae semen (Cassiae semen) is a seed of the superdestructor (Cassia obtusifolia L.), or Cassia tora L. is used as a sanitary, formal, diuretic, and laxative in oriental medicine, and in the sense of consent, it is called as a blue-eyed name (淸 肝 明目). When boiled with boiled water, the liver is known to brighten the eyes.

본 발명은 결명자를 단지 물로 끓여 추출하여 음용했을 때에는 활성성분인 노르-루브로푸사린이 전혀 들어 있지않음을 발견하고, 결명자의 주요성분인 노르-루브로푸사린의 함량이 높은 추출물을 얻기 위하여 결명자 분말을 30∼100%의 에탄올수용액으로 추출하여 고농도의 노르-루브로푸사린을 함유하는 결명자추출물을 제조하는 방법을 제공하는 것이다.The present invention finds that the active ingredient of no-lubrofusarin is not contained at all when the boiled extract extracted only by boiling with water, and to obtain an extract with a high content of noro-brobrofusarin, which is the main ingredient of the defector. It is to provide a method for producing a deficiency extract containing a high concentration of nor- lubrofusarin by extracting 30% to 100% ethanol aqueous solution.

또한, 본 발명은 옛부터 눈에 좋다로 알려져있는 결명자에 대하여 우수한 활성을 갖고 있는 추출물을 제조하고, 이들 추출물과 추출물중 함유된 활성성분의 항산화활성, 프리라디칼소거작용 및 항돌연변이효과를 확인하여 눈의 노화방지 및 안질환예방에 관한 용도를 제공하는 것이다.In addition, the present invention to prepare extracts having excellent activity against the deficiency known as good for the eye from the old, and to check the antioxidant activity, free radical scavenging action and antimutagenic effect of these extracts and the active ingredients contained in the extract It is to provide a use for the prevention of eye aging and eye diseases.

Description

결명자 추출물의 제조방법과 이들로된 항산화, 프리라디칼소거, 항돌연변이제 및 안(眼)노화방지 안질환예방제Method for preparing the extract of C. oleracea and its antioxidant, free radical elimination, antimutagenic and anti-aging eye disease prevention agents

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (3)

결명자를 분말로 한후 이를 30 내지 100% 에탄올 수용액으로 추출함을 특징으로 하는 노르-루브로푸사린을 함유하는 결명자 추출물의 제조방법.Method for preparing a defect extract containing nolu-brobrofusarin characterized in that after extracting the defect with a powder of 30 to 100% ethanol. 결명자 분말을 30 내지 100% 에탄올 수용액으로 추출하여 얻은 결명자 추출물을 주성분으로 함을 특징으로 하고 여기에 이성화당, 부형제 및 기타 약학적으로 허용되는 첨가물이 첨가될 수 있는 항산화, 프리라디칼 소거작용 및 항돌연변이제.It is characterized in that the extract is extracted from the 30% to 100% ethanol aqueous solution, as a main component, to which antioxidant, free radical scavenging and anti-oxidation, to which isosaccharides, excipients and other pharmaceutically acceptable additives can be added. Mutant. 결명자 분말을 30 내지 100% 에탄올 수용액으로 추출하여 얻은 결명자가 추출물을 주성분으로 함을 특징으로 하고 여기에 이성화당, 형제 및 기타 약학적으로 허용되는 첨가물이 첨가될 수 있는 눈의 노화방지 및 안(眼)질환예방제.Anti-aging and ocular treatment of the eye, which is obtained by extracting the deficiency powder with an aqueous 30-100% ethanol solution, as the main component, and to which isosaccharides, siblings and other pharmaceutically acceptable additives can be added. Iii) disease prevention. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019950036567A 1995-10-23 1995-10-23 Process for preparing the extracts of cassiae semen, and pharmaceutical compositions containing them useful for antioxidant, free radical scavenger, antimutagent and opthalimic disease preventing agent KR0168721B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019950036567A KR0168721B1 (en) 1995-10-23 1995-10-23 Process for preparing the extracts of cassiae semen, and pharmaceutical compositions containing them useful for antioxidant, free radical scavenger, antimutagent and opthalimic disease preventing agent

Applications Claiming Priority (1)

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KR1019950036567A KR0168721B1 (en) 1995-10-23 1995-10-23 Process for preparing the extracts of cassiae semen, and pharmaceutical compositions containing them useful for antioxidant, free radical scavenger, antimutagent and opthalimic disease preventing agent

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KR970020112A true KR970020112A (en) 1997-05-28
KR0168721B1 KR0168721B1 (en) 1999-01-15

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100478136B1 (en) * 2001-10-24 2005-03-21 주식회사 내츄로바이오텍 Extracts derived from plant that have anti-oxidation activity

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100406158B1 (en) * 2001-03-06 2003-11-15 조진원 The human body a poisonous toxic substance eliminate waste matter from the system natural product a manufacturing process
KR100444124B1 (en) * 2001-08-16 2004-08-09 이회선 Composition for inhibiting mycotoxin production
KR100765436B1 (en) * 2005-10-25 2007-10-09 경북대학교 산학협력단 Methods for increasing aurantio-obtusin content in Cassiae Semen, and the method for extraction of aurantio-obtusin having increased contents
KR100730302B1 (en) * 2005-11-24 2007-06-19 (주)이노팜 Composition comprising the extract of Cassiae Semen for treating or preventing cognitive dysfunction

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100478136B1 (en) * 2001-10-24 2005-03-21 주식회사 내츄로바이오텍 Extracts derived from plant that have anti-oxidation activity

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