KR970010881A - A composition for forming an ion selective membrane provided on an electrode of a chloride ion sensor and a method for forming an ion selective membrane using the same - Google Patents

A composition for forming an ion selective membrane provided on an electrode of a chloride ion sensor and a method for forming an ion selective membrane using the same Download PDF

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KR970010881A
KR970010881A KR1019950026775A KR19950026775A KR970010881A KR 970010881 A KR970010881 A KR 970010881A KR 1019950026775 A KR1019950026775 A KR 1019950026775A KR 19950026775 A KR19950026775 A KR 19950026775A KR 970010881 A KR970010881 A KR 970010881A
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ion
weight
chloride
selective membrane
composition
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KR1019950026775A
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KR0185781B1 (en
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차근식
남학현
차민종
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차근식
김동진
주식회사 카스
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/04—Polysiloxanes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/0016—Plasticisers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/16—Nitrogen-containing compounds
    • C08K5/17—Amines; Quaternary ammonium compounds
    • C08K5/19—Quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D183/00—Coating compositions based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon only; Coating compositions based on derivatives of such polymers
    • C09D183/04—Polysiloxanes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/333—Ion-selective electrodes or membranes
    • G01N27/3335—Ion-selective electrodes or membranes the membrane containing at least one organic component

Abstract

본 발명은 염화이온센서의 전극에 구비되는 염화이온 선택성 막을 형성하기 위한 조성물 및 이것을 사용하여 염화이온 선택성 막을 형성하는 방법에 관한 것이다. 본 발명의 조성물은 실리콘 러버, 이온 선택성 물질로서 테트라데실트리메틸암모늄 클로라이드 1∼20중량% 및 유용성 가소제 0∼40중량%로 이루어진다. 본 발명의 조성물을 사용하여 형성한 염화이온 선택성 막은 고체상 전극 표면에 형성되는 경우에는 고체상 전극 표면에 대한 접착력과 전기 화학적 성질이 우수하여 염화이온에 대한 감응성의 문제 및 짧은 수명의 문제를 해소하여 염화이온 센서의 소형화를 가능하게 한다. 또한 본 발명에 따른 조성물로 형성된 염화이온 선택성 막이 적용되는 재래식 전극 또는 고체상 전극은 이들을 구비한 염화이온 센서를 사용하여 생체물질 중 염화이온의 정량분석시 살리실레이트이온에 의한 방해작용을 받지 않을 뿐만 아니라 pH 5.5∼10.5 범위의 생체물질에서 수산화 이온에 의한 방해작용을 받지 않음으로써, 측정 신뢰도를 한층 더 향상시킬 수 있다는 효과가 있다.The present invention relates to a composition for forming a chloride ion selective membrane provided on an electrode of a chloride ion sensor and a method of forming a chloride ion selective membrane using the same. The composition of the present invention consists of silicone rubber, 1-20% by weight of tetradecyltrimethylammonium chloride as an ion-selective material and 0-40% by weight of an oil-soluble plasticizer. When the chloride ion selective membrane formed using the composition of the present invention is formed on the surface of the solid phase electrode, the chloride ion selective membrane has excellent adhesion and electrochemical properties to the surface of the solid phase electrode, thereby eliminating the problem of sensitivity to chloride ion and the problem of short life. Allows the miniaturization of the ion sensor. In addition, the conventional electrode or solid-state electrode to which the chloride ion selective membrane formed of the composition according to the present invention is applied does not have an interference effect by salicylate ion in the quantitative analysis of chloride ion in a biological material using a chloride ion sensor provided therewith. However, by not being disturbed by hydroxide ions in the biological material in the pH range of 5.5 to 10.5, there is an effect that the measurement reliability can be further improved.

Description

염화이온센서의 전극에 구비되는 이온 선택성 막을 형성하기 위한 조성물 및 이것을 사용하여 이온 선택성 막을 형성하는 방법A composition for forming an ion selective membrane provided on an electrode of a chloride ion sensor and a method for forming an ion selective membrane using the same

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

제1도는 재래식 이온 선택성 막 전극과 고체상 이온 선택성 막 전극의 단면도로, (가)는 재래식 이온 선택성 막 전극이고, (나)는 고체상 이온 선택성 막 전극이며,1 is a cross-sectional view of a conventional ion selective membrane electrode and a solid ion selective membrane electrode, (a) is a conventional ion selective membrane electrode, (b) is a solid ion selective membrane electrode,

제2도는 PVC-지지체, SR-지지체 염화이온 선택성 막을 재래식 전극에 장착하였을 때의 염화이온에 대한 감응특성의 그래프이고,2 is a graph of the sensitivity to chloride ions when the PVC-supported, SR-supported chloride ion selective membrane is mounted on a conventional electrode.

제3도는 PVC-지지체, SR-지지체 염화이온 선택성 막을 재래식 전극에 장착하였을 때의 살리실레이트이온에 대한 감응특성의 그래프이고,3 is a graph of the sensitivity to salicylate ion when a PVC-supported, SR-supported chloride ion selective membrane was mounted on a conventional electrode.

제4도는 가소제를 첨가한 SR-지지체 염화이온 선택성 막을 재래식 전극에 장착하였을 때의 감응특성을 그래프로서, (가)는 염화이온에 대한 감응성의 그래프이고, (나)는 살리실레이트이온에 대한 감응성의 그래프이며,4 is a graph showing the sensitivity of the SR-supporting chloride ion selective membrane with a plasticizer added to a conventional electrode, (A) is a graph of sensitivity to chloride ions, and (B) is a graph of salicylate ion. Is a graph of sensitivity,

제5도는 가소제를 첨가하지 않은 SR-지지체의 염화이온 선택성 막을 재래식 전극에 장착하였을 때의 감응특성을 그래프로서, (가)는 염화이온에 대한 감응성의 그래프이고, (나)는 살리실레이트이온에 대한 감응성의 그래프이며,FIG. 5 is a graph showing the sensitivity of a conventional SR-supported SR-supported membrane mounted on a conventional electrode, (A) is a graph of sensitivity to chloride ions, and (B) is a salicylate ion Is a graph of sensitivity to,

제6도는 가소제를 첨가한 SR-지지체 염화이온 선택성 막의 수산화이온에 대한 감응특성의 그래프이고,6 is a graph of the sensitivity of the SR-supporting chloride ion selective membrane with plasticizer to the hydroxide ion,

제7도는 가소제를 첨가한 SR-지지체 염화이온 선택성 막을 고체상 전극에 장착하여 유니버샬(Universal) pH7.4 완충용액에서의 감응특성의 그래프로서, (가)는 염화이온에 대한 감응성의 그래프이고, (나)는 살리실레이트이온에 대한 감응성의 그래프이다.FIG. 7 is a graph of the sensitivity of universal pH 7.4 buffer solution by attaching a plasticizer-added SR-supporting chloride ion selective membrane to a solid-state electrode, wherein (a) is a graph of sensitivity to chloride ion. B) is a graph of sensitivity to salicylate ion.

Claims (10)

실리콘 러버 89∼90중량% 및 이온 선택성 물질로서 테트라데실트리메틸암모늄 클로라이드 1∼20중량% 으로 이루어진 것을 특징으로 하는 염화이온센서의 재래식 전극 또는 고체상 전극에 적용되는 이온 선택성 막을 형성하기 위한 조성물.A composition for forming an ion selective membrane applied to a conventional electrode or a solid phase electrode of a chloride ion sensor, comprising 89 to 90% by weight of silicon rubber and 1 to 20% by weight of tetradecyltrimethylammonium chloride as an ion selective material. 실리콘 러버 40∼98중량%, 이온 선택성 물질로서 테트라데실트리메틸암모늄 클로라이드 1∼20중량% 및 유용성 가소제 1∼40중량%로 이루어진 것을 특징으로 하는 염화이온센서의 재래식 전극 또는 고체상 전극에 적용되는 이온 선택성 막을 형성하기 위한 조성물.Ion selectivity applied to conventional electrodes or solid-state electrodes of a chloride ion sensor, comprising 40 to 98% by weight of silicone rubber, 1 to 20% by weight of tetradecyltrimethylammonium chloride as an ion-selective material, and 1 to 40% by weight of an oil-soluble plasticizer. A composition for forming a film. 제2항에 있어서, 유용성 가소제는 비스(2-에틸헥실)아디페이트, 비스(2-에틸헥실)세바케이트, 2-니트로페닐 옥틸 에테르, 디에틸 숙신에이트, 디옥틸 말레이트 및 디운데실 프탈레이트로 이루어진 그룹에서 선택되는 것을 특징으로 하는 조성물.The oil-soluble plasticizer according to claim 2, wherein the oil-soluble plasticizer is bis (2-ethylhexyl) adipate, bis (2-ethylhexyl) sebacate, 2-nitrophenyl octyl ether, diethyl succinate, dioctyl malate and diundecyl phthalate Compositions selected from the group consisting of. 염화이온 센서의 고체상 전극 표면에 이온 선택성 막을 형성하기 위한 방법에 있어서, 실리콘 러버 80∼99중량% 및 이온 선택성 물질로서 테트라데실트리메틸암모늄 클로라이드 1∼20중량%로 이루어진 조성물을 유기용매에 녹여서 고체상 전극 표면에 코팅하는 공정을 포함하는 것을 특징으로 하는 방법.In the method for forming an ion-selective membrane on the surface of a solid-state electrode of a chloride ion sensor, a composition comprising 80 to 99% by weight of silicon rubber and 1 to 20% by weight of tetradecyltrimethylammonium chloride as an ion-selective material is dissolved in an organic solvent to And coating the surface. 염화이온 센서의 고체상 전극 표면에 이온 선택성 막을 형성하기 위한 방법에 있어서, 실리콘 러버 40∼98중량%, 이온 선택성 물질로서 테트라데실트리메틸암모늄 클로라이드 1∼20중량% 및 유용성 가소제 1∼40중량%로 이루어진 조성물을 유기용매에 녹여서 고체상 전극 표면에 코팅하는 공정을 포함하는 것을 특징으로 하는 방법.A method for forming an ion selective membrane on the surface of a solid-state electrode of a chloride ion sensor, comprising 40 to 98% by weight of silicon rubber, 1 to 20% by weight of tetradecyltrimethylammonium chloride as an ion selective material, and 1 to 40% by weight of an oil-soluble plasticizer. Dissolving the composition in an organic solvent to coat the surface of the solid electrode. 제5항에 있어서, 유용성 가소제는 비스(2-에틸헥실)아디페이트, 비스(2-에틸헥실)세바케이트, 2-니트로페닐 옥틸 에테르, 디에틸 숙신에이트, 디옥틸 말레이트 및 디운데실 프탈레이트로 이루어진 그룹에서 선택되는 것을 특징으로 하는 방법.6. The oil soluble plasticizer according to claim 5, wherein the oil-soluble plasticizer is bis (2-ethylhexyl) adipate, bis (2-ethylhexyl) sebacate, 2-nitrophenyl octyl ether, diethyl succinate, dioctyl malate and diundecyl phthalate. Method selected from the group consisting of. 염화이온 센서의 재래식 전극에 구비되는 이온 선택성 막을 제조하기 위한 방법에 있어서, 실리콘 러버 80∼99중량% 및 이온 선택성 물질로서 테트라데실트리메틸암모늄 클로라이드 1∼20중량%로 이루어진 조성물을 유기용매에 녹여서 용액을 형성하는 공정 및 상기의 용액을 유리판 또는 테프론 위의 유리링에 부어서 건조시킨 후 성형하는 공정을 포함하는 것을 특징으로 하는 방법.In the method for producing an ion-selective membrane provided in the conventional electrode of the chloride ion sensor, a composition comprising 80 to 99% by weight of silicon rubber and 1 to 20% by weight of tetradecyltrimethylammonium chloride as an ion-selective material is dissolved in an organic solvent Forming a solution by pouring the solution into a glass ring on a glass plate or Teflon, drying and molding. 염화이온 센서의 재래식 전극에 구비되는 이온 선택성 막을 제조하기 위한 방법에 있어서, 실리콘 러버 80∼99중량%, 이온 선택성 물질로서 테트라데실트리메틸암모늄 클로라이드 1∼20중량% 및 유용성 가소제 1∼40중량%로 이루어진 조성물을 유기용매에 녹여서 용액을 형성하는 공정 및 상기의 용액을 유리판 또는 테프론 위의 유리링에 부어서 건조시킨 후 성형하는 공정을 포함하는 것을 특징으로 하는 방법.In the method for producing an ion-selective membrane provided in the conventional electrode of the chloride ion sensor, 80 to 99% by weight of silicon rubber, 1 to 20% by weight of tetradecyltrimethylammonium chloride as the ion-selective material, and 1 to 40% by weight of the oil-soluble plasticizer. Forming a solution by dissolving the composition in an organic solvent; and drying the solution by pouring the solution onto a glass plate or a glass ring on Teflon, followed by molding. 제8항에 있어서, 유용성 가소제는 비스(2-에틸헥실)아디페이트, 비스(2-에틸헥실)세바케이트, 2-니트로페닐 옥틸 에테르, 디에틸 숙신에이트, 디옥틸 말레이트 및 디운데실 프탈레이트로 이루어진 그룹에서 선택되는 것을 특징으로 하는 방법.The oil-soluble plasticizer according to claim 8, wherein the oil-soluble plasticizer is bis (2-ethylhexyl) adipate, bis (2-ethylhexyl) sebacate, 2-nitrophenyl octyl ether, diethyl succinate, dioctyl malate and diundecyl phthalate Method selected from the group consisting of. 생체 시료를 완충 용액으로 희석하여 상기 생체 시료를 pH 5.5∼10.5로 고정시키는 공정 및 상기의 고정된 pH값을 지나는 생체 시료를 제1항 또는 제2항에 따른 조성물로 형성된 염화이온 선택성 막을 구비하는 염화이온 센서를 사용하여 정량 분석하는 공정을 포함하는 것을 특징으로 하는 수산화이온에 의한 방해작용을 받지 않는 생체 시료중의 염화이온의 정량 분석방법.Diluting the biological sample with a buffer solution to fix the biological sample to pH 5.5 to 10.5, and the biological sample passing through the fixed pH value, wherein the biological sample has a chloride ion selective membrane formed of the composition according to claim 1. A method for quantitative analysis of chloride ions in a biological sample which is not disturbed by hydroxide ions, characterized in that it comprises a step of quantitative analysis using a chloride ion sensor. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019950026775A 1995-08-26 1995-08-26 Composition for chlorine ion sensor and membrane therefrom KR0185781B1 (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101217734B1 (en) * 2010-07-26 2013-01-03 경북대학교 산학협력단 Manufacturing method of amperometric ion-selective microelectrode, amperometric ion-selective microelectrode made by the same, and electrochemical measuring method of ion concentration using the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101217734B1 (en) * 2010-07-26 2013-01-03 경북대학교 산학협력단 Manufacturing method of amperometric ion-selective microelectrode, amperometric ion-selective microelectrode made by the same, and electrochemical measuring method of ion concentration using the same

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