KR970005290A - Method for stabilizing herbal medicines containing cold medicine components and stabilized solutions - Google Patents

Method for stabilizing herbal medicines containing cold medicine components and stabilized solutions Download PDF

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Publication number
KR970005290A
KR970005290A KR1019950019850A KR19950019850A KR970005290A KR 970005290 A KR970005290 A KR 970005290A KR 1019950019850 A KR1019950019850 A KR 1019950019850A KR 19950019850 A KR19950019850 A KR 19950019850A KR 970005290 A KR970005290 A KR 970005290A
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South Korea
Prior art keywords
poloxamer
gum
ingredients
herbal
herbal medicines
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KR1019950019850A
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Korean (ko)
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KR0183183B1 (en
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양태선
탁희천
김학형
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박해룡
고려제약 주식회사
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Priority to KR1019950019850A priority Critical patent/KR0183183B1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

본 발명은 감기약 성분중 생약성분과 양약성분을 가용화시켜서 액제를 제조함에 있어서, 생약성분 및 양약성분과 기타성분을 혼합하고 여기에 검류 및 폴록사머를 첨가하여 가용화시킨 조성물 및 그 가용화방법에 관한 것이며, 이렇게 제조된 조성물은 첨전이 생성되지 않을 뿐만아니라 장기간 안정하게 보존할 수 있다.The present invention relates to a composition and a solubilization method of a solubilizing herbal medicine and medicinal ingredients in the common cold medicine component, solubilizing the herbal and medicinal ingredients and other ingredients and adding solubilizing gums and poloxamer thereto. In addition, the composition thus prepared does not produce electric charge and can be stably stored for a long time.

Description

감기약 성분을 함유하는 한방액제의 안정화 방법 및 이 안정화된 액제Method for stabilizing herbal medicines containing cold medicine components and stabilized solutions

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (8)

감기약 성분중 생약성분 및 양약성분을 가용화시켜서 액제를 제조함에 있어서, 생약성분 및 양약성분 및 기타 유효성분을 혼합하고 여기에 Gum류 및 Poloxamer를 첨가하여 가용화 및 안정화시키는 방법.Method of solubilizing and stabilizing herbal medicines and medicinal ingredients by solubilizing herbal medicines and medicinal ingredients in cold medicine ingredients, adding herbal ingredients, medicinal ingredients and other active ingredients, and adding Gum and Poloxamer to them. 제1항에서, 생약성분으로 갈근탕, 소청룡탕, 향소산, 감초 및 길경에서 선택된 생약성분을 사용하는 방법.The method of claim 1, wherein the herbal ingredients selected from galguntang, Socheongryongtang, Hyangsosan, licorice and Gilkyung as a herbal ingredient. 제1항에서, 양약성분으로 클로로페닐아민 말리에이트, 페닐프로판올아민, 카페인, 라이소자임, 세미알칼리프로테아제, 아세트아미노펜, 덱스트로메트로판 및 구아이페네신에서 선택된 양약을 사용하는 방법.The method according to claim 1, wherein a medicament selected from chlorophenylamine maleate, phenylpropanolamine, caffeine, lysozyme, semi-alkaline protease, acetaminophen, dextrometophan and guapefensine is used as a medicinal ingredient. 제1항에서 Gum류로, 산탄검, 구아검, 아라비아검, 트라가칸트검에서 선택된 검류를 0.01-10%를 함유하고, Poloxamer로서 폴록사머 124, 폴록사머 188, 폴록사머 237, 폴록사머 338 및 폴록사머 407에서 선택된 폴록사머를 0.01-50%를 사용하는 방법.The gums of claim 1, which contain 0.01-10% of gum selected from xanthan gum, guar gum, gum arabic, and tragacanth gum, and as oxoxamer poloxamer 124, poloxamer 188, poloxamer 237, poloxamer 338 and Using 0.01-50% of the poloxamer selected from poloxamer 407. 감기약 성분중 생약성분 및 양약성분을 가용화시켜서 약제를 제조함에 있어서, 생약성분 및 양약성분 및 기타 유효성분을 혼합하고 여기에 Gum류 및 Poloxamer를 첨가하여 가용화 및 안정화시킨 액제.In the preparation of a medicament by solubilizing herbal medicines and medicinal ingredients in the cold medicine ingredients, herbal medicines and medicinal ingredients and other active ingredients are mixed and solubilized and stabilized by adding Gum and Poloxamer to it. 제5항에서, 생약성분으로 갈근탕, 소청룡탕, 향소산, 감초 및 길경에서 선택된 생약성분을 함유하는 액제.The liquid preparation according to claim 5, wherein the herbal ingredient contains a herbal ingredient selected from Galguntang, Socheongryongtang, Hyangsosan, Licorice, and Gilkyung. 제5항에서, 양약성분으로 클로로페닐아민말이에이트, 페닐프로판올아민, 카페인, 라이소자임, 세미알칼리프로테아제, 아세트아미노펜, 덱스트로메트로판 및 구아이페네신에서 선택된 양약을 함유하는 액제.6. A liquid formulation according to claim 5, wherein the medicament contains a medicament selected from chlorophenylamine malate, phenylpropanolamine, caffeine, lysozyme, semi-alkaline protease, acetaminophen, dextrometophan and guapenesine. 제5항에서, Gum류로 산탄검, 구아검, 아리비아검, 트라가칸트검에서 선택된 검류를 0.01-10%를 함유하고, Poloxamer로서 폴록사머 124, 폴록사머 188, 폴록사머 237, 폴록사머 338 및 폴록사머 407에서 선택된 폴록사머를 0.01-50%를 함유하는 액제.The method of claim 5, wherein Gum contains 0.01-10% of gum selected from xanthan gum, guar gum, aribian gum, and tragacanth gum, and Poloxamer 124, Poloxamer 188, Poloxamer 237, Poloxamer 338 as Poloxamer. And a liquid formulation containing 0.01-50% of the poloxamer selected from poloxamer 407. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019950019850A 1995-07-06 1995-07-06 Stabilizing method of emulsion type-kampo drug and the stabilized kampo drug KR0183183B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019950019850A KR0183183B1 (en) 1995-07-06 1995-07-06 Stabilizing method of emulsion type-kampo drug and the stabilized kampo drug

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950019850A KR0183183B1 (en) 1995-07-06 1995-07-06 Stabilizing method of emulsion type-kampo drug and the stabilized kampo drug

Publications (2)

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KR970005290A true KR970005290A (en) 1997-02-19
KR0183183B1 KR0183183B1 (en) 1999-05-01

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