KR960022428A - The new production method of the cinnamic acid derivative - Google Patents

The new production method of the cinnamic acid derivative Download PDF

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Publication number
KR960022428A
KR960022428A KR1019940034167A KR19940034167A KR960022428A KR 960022428 A KR960022428 A KR 960022428A KR 1019940034167 A KR1019940034167 A KR 1019940034167A KR 19940034167 A KR19940034167 A KR 19940034167A KR 960022428 A KR960022428 A KR 960022428A
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KR
South Korea
Prior art keywords
cinnamic acid
formula
acid derivative
production method
compound
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KR1019940034167A
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Korean (ko)
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KR100212490B1 (en
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김윤철
채헌승
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이웅열
주식회사 코오롱
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Priority to KR1019940034167A priority Critical patent/KR100212490B1/en
Publication of KR960022428A publication Critical patent/KR960022428A/en
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Publication of KR100212490B1 publication Critical patent/KR100212490B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/10—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide
    • C07C51/12—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide on an oxygen-containing group in organic compounds, e.g. alcohols

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

본 발명은 다음 구조식 (Ⅱ)의 화합물을 NaOCH3촉매하에서 다음 구조식 (Ⅲ)의 화합물과 축합반응시켜서 신남산메틸에스테르 유도체를 얻고, 이를 가수분해하여 다음 구조식 (Ⅰ)의 신남산 유도체를 제조하는 방법에 관한 것이다.The present invention condensation reaction of a compound of formula (II) with a compound of formula (III) under a NaOCH 3 catalyst to obtain a cinnamic acid methyl ester derivative, which is hydrolyzed to prepare a cinnamic acid derivative of the following formula (I) It is about a method.

식 중, R은 수소원자 또는 매톡시기를 나타낸다.In the formula, R represents a hydrogen atom or a methoxy group.

본 발명에 의해 제공되는 새로운 신남산 유도체의 제조방법은 출발물질이 저렴하며, 반응성이 우수하고 정제공정이 간단한 새로운 경제적인 제조방법이다.The method for preparing a new cinnamic acid derivative provided by the present invention is a new economical production method with low starting materials, excellent reactivity and simple purification process.

Description

신남산 유도체의 새로운 제조방법The new production method of the cinnamic acid derivative

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (2)

하기 구조식 (Ⅱ) 화합물을, 촉매로서 NaOCH3를 일반식 (Ⅱ) 화합물 대기 반응 몰비로 0.5∼5당량 사용하여 하기 구조식(Ⅲ)의 화합물과 반응시키고, 이를 가수분해 하여 하기 일반식(Ⅰ)의 신남산 유도체를 제조하는 방법.NaOCH 3 is reacted with a compound of the following formula (III) by using 0.5 to 5 equivalents of NaOCH 3 as a catalyst in an atmospheric molar ratio of the general formula (II) compound as a catalyst. Method for preparing cinnamic acid derivatives. 식 중, R은 수소원자 또는 매톡시기를 의미한다.In the formula, R means a hydrogen atom or a methoxy group. 제1항에서, 반응시 온도가 20∼60℃, 가수분해시 온도가 50∼100℃임을 특징으로 하는 방법.The method of claim 1, wherein the temperature during the reaction is 20 to 60 ℃, the temperature during the hydrolysis is 50 to 100 ℃. ※ 참고사항:최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019940034167A 1994-12-14 1994-12-14 Method of producing cinnamic acid KR100212490B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019940034167A KR100212490B1 (en) 1994-12-14 1994-12-14 Method of producing cinnamic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019940034167A KR100212490B1 (en) 1994-12-14 1994-12-14 Method of producing cinnamic acid

Publications (2)

Publication Number Publication Date
KR960022428A true KR960022428A (en) 1996-07-18
KR100212490B1 KR100212490B1 (en) 1999-08-02

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ID=19401456

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940034167A KR100212490B1 (en) 1994-12-14 1994-12-14 Method of producing cinnamic acid

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KR (1) KR100212490B1 (en)

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Publication number Publication date
KR100212490B1 (en) 1999-08-02

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