KR960010017A - Extract active ingredients from phosphorus. Method of purification and herbal composition containing the extract - Google Patents

Extract active ingredients from phosphorus. Method of purification and herbal composition containing the extract Download PDF

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Publication number
KR960010017A
KR960010017A KR1019950026859A KR19950026859A KR960010017A KR 960010017 A KR960010017 A KR 960010017A KR 1019950026859 A KR1019950026859 A KR 1019950026859A KR 19950026859 A KR19950026859 A KR 19950026859A KR 960010017 A KR960010017 A KR 960010017A
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KR
South Korea
Prior art keywords
phosphorus
extract
active ingredient
inflammatory analgesic
purification
Prior art date
Application number
KR1019950026859A
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Korean (ko)
Other versions
KR0163813B1 (en
Inventor
한창균
박병욱
곽의종
강삼식
장현욱
손건호
김현표
Original Assignee
김준웅
주식회사 선경인더스트리
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Publication of KR960010017A publication Critical patent/KR960010017A/en
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Publication of KR0163813B1 publication Critical patent/KR0163813B1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

본 발명은 인동으로부터 유효활성 성분을 추출하는 방법과 그 추출물을 함유한 생약조성물에 관한 것으로서, 더욱 상세하게는 한약재로 사용되는 인동의 잎과 줄기의 혼합비율로 조절하고 그로부터 유효성분의 추출방법을 특정화하므로써 소염진통 활성이 우수한 유효성분을 효율적으로 추출·정제하는 방법과 그 추출·정제된 엑기스를 함유한 생약 조성물에 관한 것이다.The present invention relates to a method for extracting an active ingredient from phosphorus and a herbal composition containing the extract, and more particularly, to adjust the mixing ratio of the leaves and stems of the phosphorus used as a herbal medicine and to extract the active ingredient therefrom. The present invention relates to a method for efficiently extracting and purifying an effective ingredient having excellent anti-inflammatory analgesic activity and to a herbal composition containing the extracted and purified extract.

Description

인동으로부터 유효활성 성분을 추출·정제하는 방법과 그 추출물을 함유한 생약조성물Extraction and Purification of Active Active Ingredients from Phosphorus and Herbal Composition Containing the Extracts

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (8)

인동으로부터 유효활성 성분을 추출·정제함에 있어서, 인동의 꽃이 지고난 후 채취하여 건조하고 마쇄한 인동줄기와 인도의 개화기에 재취하여 건조하고 마쇄한 인동잎을 7:3 내지 5:5의 중량비로 혼합하여 물로 환류 추출한 후에 정제하는 것을 특징으로 하는 인동으로부터 유효활성 성분을 추출·정제하는 방법In extracting and purifying the active ingredient from the phosphorus, the weight of the dried and ground phosphorus leaves is collected after harvesting the flowers of the phosphorus and collected in the dried and ground phosphorus stem and the flowering stage of India. And extracting and purifying the active ingredient from the phosphorus, characterized in that the mixture is purified by reflux with water and purified after mixing. 제1항에 있어서, 상기 정제는 환류 추출한 후에 여과하고 그 여액에다 동량의 수포화 저급알콜을 첨가하여 층분리한 다음, 저급 알콜층을 감압·농축하여 분말 엑기스를 얻는 과정으로 시행함을 특징으로 하는 인동으로부터 유효활성 성분을 추출·정제하는 방법The method of claim 1, wherein the purification is performed by reflux extraction, filtration and layer separation by adding the same amount of saturated saturated alcohol to the filtrate, followed by depressurizing and concentrating the lower alcohol layer to obtain a powder extract. Extraction and Purification of Active Active Ingredients from Phosphorus 제2항에 있어서, 상기 수포화 저급알콜은 부틸알콜 또는 프로필알콜의 포화수용액인 것을 특징으로 하는 인동으로부터 유효활성 성분을 추출·정제하는 방법The method for extracting and purifying the active ingredient from phosphorus according to claim 2, wherein the saturated lower alcohol is a saturated aqueous solution of butyl alcohol or propyl alcohol. 인동으로부터의 추출한 유효생리 활성물질을 함유하는 생약조성물에 있어서, 로니세로사이드(Loniceroside) A가 0.5∼3.0중량%, 로니세로사이드 B가 0.5∼3.0중량%, 로니세린(Lonicerin)이 0.5∼2.0중량%, 로가닌(Loganin)이 2.0∼5.0중량% 함유되어 있는 것을 특징으로 하는 생약조성물In the herbal composition containing an effective physiologically active substance extracted from phosphorus, 0.5-3.0 wt% of Loniceroside A, 0.5-3.0 wt% of Lonieroside B, 0.5-2.0 wt% of Lonicerin Herb composition comprising 2.0% to 5.0% by weight of Loganin 상기 제4항의 생약조성물을 유효성분으로 하는 소염 진통제Anti-inflammatory analgesic using the herbal composition of claim 4 as an active ingredient 제5항에 있어서, 제형이 연고제인 것을 특징으로 하는 소염 진통제The anti-inflammatory analgesic according to claim 5, wherein the formulation is an ointment. 제5항에 있어서, 제형이 정제인 것을 특징으로 하는 소염 진통제The anti-inflammatory analgesic according to claim 5, wherein the formulation is a tablet. 제5항에 있어서, 제형이 주사제인 것을 특징으로 하는 소염 진통제The anti-inflammatory analgesic according to claim 5, wherein the formulation is an injection. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019950026859A 1994-09-29 1995-08-28 Process for extracting and purification method of pharmacologally effective components for capriofoliaceae and crude drug composition containing the extract KR0163813B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19940024803 1994-09-29
KR94-24803 1994-09-29

Publications (2)

Publication Number Publication Date
KR960010017A true KR960010017A (en) 1996-04-20
KR0163813B1 KR0163813B1 (en) 1998-12-01

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KR1019950026859A KR0163813B1 (en) 1994-09-29 1995-08-28 Process for extracting and purification method of pharmacologally effective components for capriofoliaceae and crude drug composition containing the extract

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100672036B1 (en) * 1999-01-22 2007-01-19 에스케이케미칼주식회사 Asthma Therapeutics using Lonicera japonica extracts
JP2006510592A (en) * 2002-09-11 2006-03-30 エスケー ケミカルズ カンパニー リミテッド Extraction and purification method of active component of honeysuckle (LonicerajaponicaThumb.) Stem, its use for anti-inflammatory analgesic
KR101158835B1 (en) * 2009-12-07 2012-06-27 강원대학교산학협력단 Anti-inflammatory pharmaceutical composition comprising the extracts from Broussonetia papyrifera and Lonicera japonica

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KR0163813B1 (en) 1998-12-01

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