KR940701257A - 류우머티 치료약 - Google Patents
류우머티 치료약Info
- Publication number
- KR940701257A KR940701257A KR1019930704110A KR930704110A KR940701257A KR 940701257 A KR940701257 A KR 940701257A KR 1019930704110 A KR1019930704110 A KR 1019930704110A KR 930704110 A KR930704110 A KR 930704110A KR 940701257 A KR940701257 A KR 940701257A
- Authority
- KR
- South Korea
- Prior art keywords
- fluorouracil
- produces
- rheumatism
- murty
- ryu
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
부작용이 적고, 높은 안전성을 갖는 동시에 치료효과가 뛰어난 새로운 류우머티 치료약인 5-플루오로 우라실 또는 체내에서 5-플루오로 우라실을 생성하는 5-플루오로 우라실의 N-치환체를 약효성분으로서 함유하는 류우머티 치료약이 기재되어 있다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (2)
- 5-플루오로 우라실 또는 체내에서 5-플루오로 우라실을 생성하는 5-플루오로 우라실의 N-치환체를 약효성분으로서 함유하는 류우머티 치료약.
- 제1항에 있어서, 우라실을 함유하는 류우머티 치료약.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4139705A JPH05310573A (ja) | 1992-05-01 | 1992-05-01 | リウマチ治療薬 |
| JP92-139705 | 1992-05-01 | ||
| PCT/JP1993/000587 WO1993021922A1 (en) | 1992-05-01 | 1993-04-30 | Antirheumatic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR940701257A true KR940701257A (ko) | 1994-05-28 |
Family
ID=15251503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019930704110A KR940701257A (ko) | 1992-05-01 | 1993-04-30 | 류우머티 치료약 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5530003A (ko) |
| EP (1) | EP0597130A4 (ko) |
| JP (1) | JPH05310573A (ko) |
| KR (1) | KR940701257A (ko) |
| CN (1) | CN1083357A (ko) |
| AU (1) | AU4271893A (ko) |
| CA (1) | CA2112665A1 (ko) |
| WO (1) | WO1993021922A1 (ko) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716981A (en) * | 1993-07-19 | 1998-02-10 | Angiogenesis Technologies, Inc. | Anti-angiogenic compositions and methods of use |
| US20030203976A1 (en) | 1993-07-19 | 2003-10-30 | William L. Hunter | Anti-angiogenic compositions and methods of use |
| US5719132A (en) * | 1996-06-27 | 1998-02-17 | Bristol-Myers Squibb Company | Compositions and methods of treating HIV with d4T, 5-fluorouracil/tegafur, and uracil |
| WO2005042002A2 (en) * | 2003-10-30 | 2005-05-12 | Entelos, Inc. | Treatment of rhematoid arthritis with flip antagonists |
| KR100870104B1 (ko) * | 2005-11-28 | 2008-11-26 | 주식회사 머젠스 | 안구건조증 치료 및 예방용 조성물 |
| CA2681222C (en) * | 2007-03-19 | 2016-07-26 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The University Of Oregon | Mannich base n-oxide drugs |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5683420A (en) * | 1979-12-11 | 1981-07-08 | Taiho Yakuhin Kogyo Kk | Antineoplasmic composition |
| SU1178455A1 (ru) * | 1982-08-06 | 1985-09-15 | Белорусский Научно-Исследовательский Институт Неврологии,Нейрохирургии И Физиотерапии | Способ лечени больных ревматоидным артритом |
| ATE141506T1 (de) * | 1990-09-07 | 1996-09-15 | Taiho Pharmaceutical Co Ltd | Antineoplastisch wirkender und den antineoplastischen effekt verstärkender wirkstoff |
-
1992
- 1992-05-01 JP JP4139705A patent/JPH05310573A/ja active Pending
-
1993
- 1993-04-30 US US08/170,220 patent/US5530003A/en not_active Expired - Fee Related
- 1993-04-30 CA CA002112665A patent/CA2112665A1/en not_active Abandoned
- 1993-04-30 EP EP19930911966 patent/EP0597130A4/en not_active Withdrawn
- 1993-04-30 AU AU42718/93A patent/AU4271893A/en not_active Abandoned
- 1993-04-30 WO PCT/JP1993/000587 patent/WO1993021922A1/ja not_active Application Discontinuation
- 1993-04-30 KR KR1019930704110A patent/KR940701257A/ko not_active Application Discontinuation
- 1993-05-01 CN CN93106127A patent/CN1083357A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2112665A1 (en) | 1993-11-11 |
| US5530003A (en) | 1996-06-25 |
| WO1993021922A1 (en) | 1993-11-11 |
| EP0597130A1 (en) | 1994-05-18 |
| CN1083357A (zh) | 1994-03-09 |
| AU4271893A (en) | 1993-11-29 |
| JPH05310573A (ja) | 1993-11-22 |
| EP0597130A4 (en) | 1994-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |