KR940014775A - 세팔로스포린 c를 생산하는 미생물 및 이를 이용한 세팔로스포린 c의 제조방법 - Google Patents

세팔로스포린 c를 생산하는 미생물 및 이를 이용한 세팔로스포린 c의 제조방법 Download PDF

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KR940014775A
KR940014775A KR1019920027568A KR920027568A KR940014775A KR 940014775 A KR940014775 A KR 940014775A KR 1019920027568 A KR1019920027568 A KR 1019920027568A KR 920027568 A KR920027568 A KR 920027568A KR 940014775 A KR940014775 A KR 940014775A
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cephalosporin
microorganisms
making
methods
same
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KR1019920027568A
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KR960004037B1 (ko
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길광훈
손영선
유명규
이근철
박종성
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김정순
제일제당 주식회사
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/745—Cephalosporium ; Acremonium
    • C12R2001/75—Cephalosporium acremonium ; Acremonium strictum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/925—Cephalosporium
    • Y10S435/926—Cephalosporium acremonium

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

본 발명은 세팔로스포리움 아크레모니움 KFCC 10679로부터 중금속이온인 염화수은에 대해서 내성을 가지며 고농도로 세팔로스포린C를 생산하는 돌연변이주 KFCC 10785을 획득하여 이성화액당, 혼합오일, 콘스팁리커, 땅콩분 등이 함유된 배지중에서 배양하여 배양물로부터 세팔로스포린C를 채취하는 것을 특징으로 한다.

Description

세팔로스포린 C를 생산하는 미생물 및 이를 이용한 세팔로스포린 C의 제조방법.
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 중금속이온인 염화수은 농도가 20ug/ml이상인 조건에서도 생육할 수 있는 세팔로스포린C를 생산하는 미생물 세팔로스포리움 아크레모니움 KFCC 10785.
  2. 제1항의 미생물을 이성화액당, 혼합오일, 땅콩분, 콘스팁리커 등이 함유된 배지중에서 배양하여 세팔로스포린C를 채취하는 것을 특징으로 하는 세팔로스포린C의 제조방법.
    ※참고사항:최초출원 내용에 의하여 공개하는 것임.
KR1019920027568A 1992-12-31 1992-12-31 세팔로스포린 c를 생산하는 미생물 및 이를 이용한 세팔로스포린 c의 제조방법 KR960004037B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019920027568A KR960004037B1 (ko) 1992-12-31 1992-12-31 세팔로스포린 c를 생산하는 미생물 및 이를 이용한 세팔로스포린 c의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019920027568A KR960004037B1 (ko) 1992-12-31 1992-12-31 세팔로스포린 c를 생산하는 미생물 및 이를 이용한 세팔로스포린 c의 제조방법

Publications (2)

Publication Number Publication Date
KR940014775A true KR940014775A (ko) 1994-07-19
KR960004037B1 KR960004037B1 (ko) 1996-03-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920027568A KR960004037B1 (ko) 1992-12-31 1992-12-31 세팔로스포린 c를 생산하는 미생물 및 이를 이용한 세팔로스포린 c의 제조방법

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KR960004037B1 (ko) 1996-03-25

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