KR930023726A - 독립적으로 구동되는 복수개의 큐벳 지지링을 지니는 분석기 인큐베이터 - Google Patents

독립적으로 구동되는 복수개의 큐벳 지지링을 지니는 분석기 인큐베이터 Download PDF

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KR930023726A
KR930023726A KR1019930008916A KR930008916A KR930023726A KR 930023726 A KR930023726 A KR 930023726A KR 1019930008916 A KR1019930008916 A KR 1019930008916A KR 930008916 A KR930008916 A KR 930008916A KR 930023726 A KR930023726 A KR 930023726A
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South Korea
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rings
cuvette
addition
incubator
liquid reagent
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KR1019930008916A
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KR100226294B1 (ko
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프란시스 자쿠보위츠 레이몬드
자콥스 포르테 조하네스
엘리스 로빈슨 제임스
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알프레드 피. 로렌조
이스트만 코닥 컴퍼니
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Priority claimed from US07/887,990 external-priority patent/US5244633A/en
Priority claimed from US08/034,040 external-priority patent/US5360597A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346Heating or cooling arrangements
    • G01N2035/00356Holding samples at elevated temperature (incubation)
    • G01N2035/00376Conductive heating, e.g. heated plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements
    • G01N2035/00524Mixing by agitating sample carrier
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0439Rotary sample carriers, i.e. carousels
    • G01N2035/0444Rotary sample carriers, i.e. carousels for cuvettes or reaction vessels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0439Rotary sample carriers, i.e. carousels
    • G01N2035/0453Multiple carousels working in parallel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0439Rotary sample carriers, i.e. carousels
    • G01N2035/0458Multiple concentric rows of wells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/046General conveyor features
    • G01N2035/0462Buffers [FIFO] or stacks [LIFO] for holding carriers between operations
    • G01N2035/0463Buffers [FIFO] or stacks [LIFO] for holding carriers between operations in incubators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0474Details of actuating means for conveyors or pipettes
    • G01N2035/0482Transmission
    • G01N2035/0486Gearing, cams
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/809Incubators or racks or holders for culture plates or containers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/113332Automated chemical analysis with conveyance of sample along a test line in a container or rack
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/113332Automated chemical analysis with conveyance of sample along a test line in a container or rack
    • Y10T436/114165Automated chemical analysis with conveyance of sample along a test line in a container or rack with step of insertion or removal from test line
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/16Phosphorus containing

Abstract

본 발명은 인큐베이터(50), 및 처리 스테이션들 사이에서 액체 포함 큐벳(C)을 각각 보지 및 이동시키는 2개의 독립적으로 구동되는 인큐베이터링(52,54;52A,54A)를 사용하는 배양방법에 관한 것이다. 적어도 하나의 시약 첨가 스테이션은 2개의 링들 각각에 인접하게 영구적으로 배치된다. 그 결과 모든 시약 첨가 스테이션들을 사용함으로써 단지 하나의 링을 사용할 때보다 처리성이 향상되는 장점을 지닌다.

Description

독립적으로 구동되는 복수개의 큐벳 지지링을 지니는 분석기 인큐베이터
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 인큐베이터를 합체한 분석기의 개략적 평면도, 제2도는 인큐베이터 자체 및 그 인큐베이터에 연관된 처리 스테이션의 개략도, 제3도는 덮개가 제거된 제2도의 인큐베이터의 평면도.

Claims (1)

  1. 분석물을 검출하기 위한 분석기의 인큐베이터로서 고정 가이드 트랙; 한정된 위치들에 보지된 반응 큐벳들을 상기 인큐베이터의 처리 스테이션 사이에서 운반하기 위해 상기 트랙상에 배치된 복수개의 지지링으로서, 상기 위치들은 상기 링들내에서 상기 반을 큐벳을 수용 및 보지하는 크기로된 개구부들을 포함하는 지지링; 상기 스테이션들 사이에서 각각의 상기 지지링들을 독립적으로 회전시키는 수단; 이송위치에서 상기 큐벳을 하나의 지지링으로부터 다른 지지링까지 이동시키거나 인큐베이터내의 적절한 스테이지에서 상기 링들을 벗겨내며, 상기 링들 중 적어도 하나의 링에서 각각의 상기 큐벳 보지 개구부로부터 상기 링상의 하역위치(dump position)까지 연장되는 통로 노치(notch)를 포함하는 이동수단으로써 상기 노치와 상기 고정 가이드 트랙은 큐벳이 상기 하역 위치에 하역되도록 구성되는 이동 수단; 샘플의 첨가, 제1액체 시약 첨가, 제2액체 시약 첨가, 큐벳 세척, 임의의 제3액체 시약 첨가, 시약 큐벳으로부터 방출된 광의 검출기능을 위한 분리적 수단들을 제공하기 위해 상기 링들에 인접한 처리 스테이션들로써 적어도 상기 제1액체 반응 첨가 스테이션은 상기 링들 중 적어도 하나의 링에 인접하게 영구적으로 배치되며, 적어도 상기 제2액체 시약 첨가 스테이션은 상기 링들 중 적어도 다른 링에 인접하게 영구적으로 배치되는 처리 스테이션; 및 상기 양(兩)링들 모두에 인접 배치된 온도 조절 수단;을 포함하므로써 배양 기능들이 하나 이상의 지지링상으로 분리 및 분포되어 시간당 검출된
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930008916A 1992-05-22 1993-05-22 독립적으로 구동되는 복수개의 큐벳지지링을 지니는 분석기 인큐베이터 KR100226294B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92-887,990 1992-05-22
US07/887,990 US5244633A (en) 1992-05-22 1992-05-22 Analyzer incubator with plural independently driven rings supporting cuvettes
US08/034,040 US5360597A (en) 1993-03-22 1993-03-22 Ribbed mechanism for mixing sample by vibration

Publications (2)

Publication Number Publication Date
KR930023726A true KR930023726A (ko) 1993-12-21
KR100226294B1 KR100226294B1 (ko) 1999-10-15

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KR1019930008917A KR930023727A (ko) 1992-05-22 1993-05-22 진동운동으로 샘플을 혼합하는 리브보강(ribbed) 혼합장치
KR1019930008916A KR100226294B1 (ko) 1992-05-22 1993-05-22 독립적으로 구동되는 복수개의 큐벳지지링을 지니는 분석기 인큐베이터

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KR1019930008917A KR930023727A (ko) 1992-05-22 1993-05-22 진동운동으로 샘플을 혼합하는 리브보강(ribbed) 혼합장치

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EP (1) EP0571034A1 (ko)
JP (1) JPH0634641A (ko)
KR (2) KR930023727A (ko)
FI (1) FI932329A (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09145719A (ja) * 1995-11-21 1997-06-06 Tosoh Corp 自動分析装置用反応装置
JP3559879B2 (ja) * 1995-12-13 2004-09-02 東ソー株式会社 自動分析装置用の反応装置
KR100452403B1 (ko) * 2002-11-19 2004-10-12 한국과학기술연구원 세포배양용 복합 생물반응기
US8043562B2 (en) * 2003-12-08 2011-10-25 Ortho-Clinical Diagnostics, Inc. Analyzer having removable holders or a centrifuge
CN116794337A (zh) 2013-03-15 2023-09-22 雅培制药有限公司 具有竖直布置的圆盘传送带的自动化诊断分析仪及相关方法
EP3875963A4 (en) * 2018-10-30 2022-06-29 Shenzhen Increcare Biotech Co. Ltd Mixing method, mixing device and immunoassay analyzer
EP3875962A4 (en) * 2018-10-30 2022-06-29 Shenzhen Increcare Biotech Co. Ltd Blending method, blending apparatus, and immunoassay analyzer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3497320A (en) * 1966-12-15 1970-02-24 Xerox Corp Automated chemical analyzer
US3623844A (en) * 1969-07-17 1971-11-30 American Optical Corp Incubator and process turntable for chemical analysis apparatus for micro samples
GB1353014A (en) * 1970-03-03 1974-05-15 Hayward Foundation Analysis method apparatus and system
US5104807A (en) * 1988-02-19 1992-04-14 Hitachi, Ltd. Analyzing apparatus in which liquid can be stirred and analyzing method thereof
US5183638A (en) * 1989-12-04 1993-02-02 Kabushiki Kaisha Nittec Automatic immunity analysis apparatus with magnetic particle separation

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EP0571034A1 (en) 1993-11-24
KR100226294B1 (ko) 1999-10-15
FI932329A0 (fi) 1993-05-21
JPH0634641A (ja) 1994-02-10
FI932329A (fi) 1993-11-23
KR930023727A (ko) 1993-12-21

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