KR920005646B1 - Skin care cosmetics - Google Patents

Abstract

The skin composition is composed of 0.01-30.0 wt.% lysophospholipid as an emulsifying agent, 0.01-15.0 wt.% phytosterol and 0.01-15.0 wt.% sphingolipid as a moisture-retaining agent. The lysophospholipid is obtained by treating phospholipid with phospholipase A (or D), and improves an emulsification property and stability of a hydrophillic oil/water emulsion. The cosmetic has an excellent stability and moisture-retaining property for skin.

Description

Skin cosmetics

The present invention relates to a skin cosmetic composition containing lysophospholipids, phytosterols and sphingolipids, in particular cosmetic compositions having excellent product stability, skin safety and skin moisturizing properties.

The stratum corneum of skin maintains its smoothness and suppleness by sebum and moisture, but the difference in skin texture is largely affected by the moisture content. At this time, when the moisture is insufficient, the skin surface becomes tinged or cracked. Therefore, moisturizers, such as 1,3-butylene glycol, propylene glycol, glycerin, PCH, sodium lactate, collagen, hyaluronic acid, sorbitol, polyethylene glycol, sodium pyridone carbohydrate, etc. This prevents drying of the stratum corneum.

In addition, emulsion products are required to have good stability so that the emulsion does not separate into the water phase and the oil phase until the consumer uses the commercially available product completely.

Generally, synthetic nonionic surfactants, synthetic cationic surfactants, synthetic anionic surfactants, synthetic cationic surfactants, and the like are used as methods for improving the stability of the emulsion. However, many consumers have anxiety about the use of such synthetic surfactants.

The reason is that the aqueous solution of synthetic surfactants affects the superficial bacteria (epidermis, acne (basic), interim bacteria (gram negative bacteria, E. coli, P. aeruginosa, etc.), Staphylococcus aureus) on the skin surface. This is because it inhibits the activity, and as a result, skin resistance is reduced, which is likely to cause irritation, and at the same time, the function of keratin is reduced.

In addition, emulsion compositions containing high-fat fatty acid soaps are often used, which are relatively stable, but because they are alkaline in nature, consumers tend to be reluctant due to concern about skin irritation.

In order to improve this problem, the present inventors have conducted extensive research on the skin stability and moisturizing properties of natural emulsifiers and natural moisturizers. It was noted that the compositions using sphingolipids as emulsifiers and moisturizers, respectively, showed good results for safety and moisturization. However, the composition using only lysophospholipid as an emulsifier alone has insufficient long-term emulsification stability, and it was found that the use of phytosterol, a kind of vegetable sterol, to improve the emulsification stability as follows.

First, raw material 1-2 of Table 1 was dissolved in 80 ° C. to obtain solution A. Separately, the raw material 3-4 is put into 5 and dissolved by heating to 80 ℃ to obtain a solution B. The solution A is added to the solution B to emulsify and left at room temperature to obtain the desired emulsion composition.

TABLE 1

After 2 hours, the stability of the emulsion was calculated by examining the degree of separation of the emulsified product of each prescription. The result is as follows.

From the above results, it was found that the emulsified product of Formulation 1 using lysophospholipids and phytosterols had superior product stability compared to that of Formulation 2 using only lysophospholipids alone, and based on this finding, the present invention was completed.

The present invention relates to a skin cosmetic composition containing lysophospholipids, phytosterols and sphingolipids.

The lysolipid used in the present invention may be any kind of lysolipid obtained by treating the phospholipid with a hydrolase, that is, phospholipase A or phospholipase di, as long as it does not adversely affect the invention. Regiophospholipids can be represented by the following general formula:

(Wherein R 'and R' 'are fatty acid acyl groups, X is choline ([HOCH2CH2N (CH3) 3] OH), ethanolamine, serine (C3H7NO3), inositol (C6H6 (OH) 6))

In other words, lysphospholipids are hydrolyzed ester bonds attached to the first or second position carbons of phospholipids to remove 1 molecule of fatty acid residues with hydrophobic properties. Since the balance changes, the emulsification and stability of the hydrophilic O / W emulsion are improved.

는 지방산아실기이다)(Meal,

Is a fatty acid acyl group)

The lysolipid used in the present invention is preferably extracted from soybeans and egg yolks. For example, commercial products such as risorecithin from Nippon Co., Ltd., Japan's Sun Chemical, San Lecithin A and San Lecithin S, etc. Can be used.

The sphingolipids used in the present invention may be used with any kind of sphingolipids as long as they do not adversely affect the present invention.

Sphingolipid is a generic term for complex lipids containing sphingosine as a common component, and may be represented by the following general formula.

(Wherein X represents sugar, phosphoric acid or base, in particular galactose, glucose, choline, ethanolamide, etc., and R represents alkyl having 16-24 carbon atoms.)

In other words, sphingolipids are those in which the terminal -OH of ceramide in which fatty acid is amide-bonded to sphingosine is combined with various substances.

The sphingolipid used in the present invention is preferably extracted from bovine brain, and for example, a commercial product such as BBS, manufactured by Japan Cupid, Glycosome from Pentafam, Switzerland, and the like can be used.

The phytosterols used in the present invention may be any kind of phytosterols as long as they do not adversely affect the present invention, and the category includes phytosterol derivatives in which ethylene oxide is added to phytosterols.

Phytosterol is the generic name for phytosterin in alcohols with cyclopentanohydrophenanthrene ring, which is a mixture of beta-sitosterol, campesterol and stigmasterol in a ratio of about 2: 1: 1. It is a mixture.

The phytosterol derivative to which ethylene oxide is added refers to the addition of 5, 10, 15, 20, 25, or 50 mol of ethylene oxide to phytosterol.

The phytosterols and phytosterol ethylene oxide derivatives used in the present invention are preferably extracted from soybean or wood, for example, phytosterols from Aiza Co., Ltd., beta-sitosterols from KAUKAS Co. The same commercially available product can be used.

Cosmetic compositions of the present invention containing lysophospholipids, phytosterols and sphingolipids may be suitably formulated with moisture, humectants, thickeners, oils, preservatives, pigments, alcohols, powders, fragrances and the like within the scope of not impairing the properties of these raw materials. Can be. In general, in the cosmetic composition of the present invention, the blending amount of the lysophospholipid, the phytosterol and the sphingolipid is 0.01 wt% -30.0 wt%, 0.01 wt% -15.0 wt%, and 0.01 wt% -15.0 wt%, respectively.

Cosmetic compositions of the present invention containing lysophospholipids, phytosterols and sphingolipids can be formulated into various forms of cosmetics such as lotions, creams and the like.

The skin cosmetic composition according to the present invention is described in more detail by the following examples, which do not limit the present invention.

Example 1

Lotion

The raw material of the lotion manufactured in the present Example is as Table 2 below.

First, raw material 1-9 was dissolved by heating to 80 ° C. to obtain solution A. Separately, raw material 10-14 was added to 17 and heated to 80 ° C. to obtain solution B. The solution A is emulsified by adding the solution B, and then the raw materials 15 and 16 are added and cooled to room temperature to obtain a desired lotion composition.

[Comparative Example 1-4]

Using a raw material described in Table 2 below to prepare a cosmetic composition that can be used as a lotion by the same method as in Example 1.

TABLE 2

(weight%)

Experimental Example 1

Fifty women aged 20-40 years were compared to compare the cosmetics according to the present invention, namely, lotions containing lysolipids and sphingolipids (Example 1), conventional lotions (Comparative Example 1), and Comparative Examples 2-4. The panel test was carried out for 28 days to evaluate the usability for moisture retention (moisture) by the sensory test. The results are shown in Table 3 below.

The evaluation method evaluated the average value of 50 people by the following grade which scored 5 points.

1: very bad

2: bad

3: is normal

4: good

5: very good

Sensory test review results for the feeling of moisture

TABLE 3

As can be seen from the above results, the lotion (Example 1) composed of the composition of the present invention is satisfactory in feeling of use, whereas the lotion of Comparative Examples 1-4 is inferior to the lotion of the present invention.

In addition, the side effects panel test was performed for the lotion previously recorded, and the results are shown in Table 4 below.

The evaluation method was the average value of 50 people according to the following five grades.

4: many side effects

3: many side effects

2: is normal

1: no side effects

0: no side effects

Side effects review results

TABLE 4

As can be seen from the above results, the lotion of the present invention (Example 1) had less side effects than the conventional lotion (Comparative Example 1), and Comparative Examples 2 to 4.

In addition, in order to compare the emulsification ability, the compositions of Example 1 and Comparative Examples 1-4 were left at temperatures of 5 ° C. and 50 ° C., respectively, to investigate their stability.

The evaluation method calculates the stability (%) of the emulsion by examining the degree of separation after the same time elapsed for each lotion. The results are shown in Table 5.

Emulsion stability at each temperature (after 1 month left)

TABLE 5

From the above results, it can be seen that the lotion of the present invention using lysophospholipid, phytosterol and sphingolipid is a cosmetic having excellent stability at 5 ° C. and 50 ° C., respectively, compared to the conventional lotion and Comparative Example 2-4.

Compared to the above results, it can be seen that the lotion of the present invention using lysophospholipid, phytosterol and sphingolipid is an excellent cosmetic in terms of use (moisture), skin stability and product stability compared to conventional lotions and Comparative Examples 2-4. .

Example 2

Manufacture of cream

The raw material of the cream prepared in this example is as described in Table 6.

First, Raw Material 1-12 was dissolved by heating to 80 ° C. to obtain Solution A. Separately, Raw Material 13-17 was added to 20 and dissolved by heating to 80 ° C. to obtain Solution B. The solution A is added to solution B to emulsify and then the raw materials 18 and 19 are added and cooled to room temperature to obtain a desired cream composition.

[Comparative Example 5-8]

Using a raw material described in Table 6 below to prepare a cosmetic composition that can be used as a cream by the same method as in Example 2.

TABLE 6

Example 2

In order to compare the cosmetics according to the present invention, that is, creams containing lysophospholipids, phytosterols and sphingolipids (Example 2), and creams of Comparative Creams (Comparative Example 5) and Comparative Examples 6 to 8, In the same manner, the sensory test, side effect test, and emulsion stability test were performed. The results are shown in Tables 6-8.

Results of performance test review on the feeling of use (moisture) of the cream

TABLE 6

Side effects review results

TABLE 7

Emulsion stability at each temperature (after 1 month left)

TABLE 8

From the above results, it can be seen that the cream of the present invention using lysophospholipids, phytosterols and sphingolipids (Example 2) is a cosmetic having excellent feeling of use (moisture), skin safety and product stability compared to the creams of Comparative Examples 5-8. Can be.

Claims (3)

A cosmetic composition comprising 0.01 to 30.0% by weight of lysolipids, 0.01 to 15.0% by weight of phytosterol, and 0.01 to 15.0% by weight of sphingolipids. The cosmetic composition according to claim 1, which is in the form of a lotion. The cosmetic composition according to claim 1, which is in a cream form.