Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이승동, 주식회사 선경인더스트리filedCritical이승동
Priority to KR1019890019974ApriorityCriticalpatent/KR910011785A/en
Publication of KR910011785ApublicationCriticalpatent/KR910011785A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Hydrogenated Pyridines
(AREA)
Abstract
내용 없음No content
Description
리페리딘유도체 염산염의 제조방법Preparation method of Liperidine derivative hydrochloride
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.
Claims (2)
다음일반식(Ⅱ)로 표시되는 피페리딘유도체로부터 다음일반식(I)로 표시되는 피페리딘유도체 염산염을 제조함에 있어서, 다음일반식(Ⅱ)의 화합물을 메탄올 용매중에서 SOCl2, POCl3, PCl3또는 PCl5와 반응시키는 것을 특징으로 하는 피페리딘유도체 염산염의 제조방법.In the next as from the piperidine derivative represented by the formula (Ⅱ) preparing a piperidine derivative hydrochloride represented by the following general formula (I), SOCl 2 the compound of the general formula (Ⅱ) in methanol solvent, POCl 3 , PCl 3 or PCl 5 and the method for producing piperidine derivative hydrochloride, characterized in that the reaction.상기식들중에서, R은 수소원자 또는 탄소수 1~6개의 알킬 기를 나타내고, Ar은 아릴기를 나타내며, X는 수소원자 또는 탄소수 1 내지 3개의 저급알킬기를 나타낸다.In the above formula, R represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, Ar represents an aryl group, and X represents a hydrogen atom or a lower alkyl group having 1 to 3 carbon atoms.제1항에 있어서, 상기 반응은 -10℃~70℃에서 1~4시간동안 반응시키는 것을 특징으로 하는 피페리딘유도체 염산염의 제조방법.The method of claim 1, wherein the reaction is performed at −10 ° C. to 70 ° C. for 1 to 4 hours.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019890019974A1989-12-281989-12-28
Process for preparing piperidine derivative hydrochloride
KR910011785A
(en)