KR910004179A - 아스피린 과립 및 빠른-개시 투여 형태 - Google Patents
아스피린 과립 및 빠른-개시 투여 형태 Download PDFInfo
- Publication number
- KR910004179A KR910004179A KR1019900010583A KR900010583A KR910004179A KR 910004179 A KR910004179 A KR 910004179A KR 1019900010583 A KR1019900010583 A KR 1019900010583A KR 900010583 A KR900010583 A KR 900010583A KR 910004179 A KR910004179 A KR 910004179A
- Authority
- KR
- South Korea
- Prior art keywords
- granules
- aspirin
- fast
- individual
- aspirin granules
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (9)
- 피복된 과립이 250㎛ 보다 작은 입자 사이즈를 갖도록 위 보호(gastroprotectant) 피복물로 피복된 개개 아스피린 과립.
- 제1항에 있어서, 약 75㎛-약 150㎛의 평균 입자 사이즈를 갖는 개개 아스피린 과립.
- 제1항에 있어서, 상기 위보호 피복물이 상기 과립의 약 10%-약 75중량%를 구성하는 개개 아스피린 과립.
- 제3항에 있어서, 위보호 피복물이 상기 과립의 약 30%-약 35중량%를 구성하는 개개 아스피린 과립.
- 제1항 내지 제4항 중 어느 한 항에 있어서, 위보호 피복물이 셀룰로우스 아세테이트 프탈레이트, 폴리(비닐 아세테이트 프탈레이트), 히드록시프로필메틸셀룰로우스 프탈레이트 또는 메타크릴산과 에틸 아크릴레이트의 공중합체인 개개 아스피린 과립.
- 제5항에 있어서, 상기 위보호 피복물이 약 250,000의 평균분자량을 갖는 메타크릴산과 에틸 아크릴레이트의 1 : 1 공중합체로 구성되는 개개 아스피린 과립.
- 제1항 내지 제4항 중 어느 한 항에 따르는 과립을 포함하는 빠른-개시 투여 형태.
- 제7항에 있어서, 50-650㎎의 아스피린을 함유하는 빠른-개시 투여 형태.
- 제8항에 있어서, 약325㎎의 아스피린을 함유하는 빠른-개시 투여 형태.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39468389A | 1989-08-16 | 1989-08-16 | |
US07/394,683 | 1989-08-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR910004179A true KR910004179A (ko) | 1991-03-28 |
Family
ID=23559993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019900010583A KR910004179A (ko) | 1989-08-16 | 1990-07-12 | 아스피린 과립 및 빠른-개시 투여 형태 |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0413120A3 (ko) |
JP (1) | JPH0386827A (ko) |
KR (1) | KR910004179A (ko) |
AU (1) | AU627335B2 (ko) |
CA (1) | CA2023303A1 (ko) |
FI (1) | FI902964A0 (ko) |
IE (1) | IE902554A1 (ko) |
IL (1) | IL94735A0 (ko) |
MX (1) | MX21165A (ko) |
NO (1) | NO903116L (ko) |
NZ (1) | NZ233975A (ko) |
PT (1) | PT94552A (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2704146B1 (fr) * | 1993-04-19 | 1995-07-13 | Cripdom | Microcapsules d'acide acétylsalicylique à libération contrôlée. |
US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
CN100553625C (zh) | 2002-04-09 | 2009-10-28 | 弗拉梅技术公司 | 活性成分微囊的口服混悬液 |
WO2003084517A2 (fr) | 2002-04-09 | 2003-10-16 | Flamel Technologies | Suspension orale de microcapsules d’amoxicilline |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3906086A (en) * | 1971-07-19 | 1975-09-16 | Richard G Powers | Timed-release aspirin |
DE3264867D1 (en) * | 1981-04-27 | 1985-08-29 | Haessle Ab | New pharmaceutical preparation |
GB2132887A (en) * | 1982-11-15 | 1984-07-18 | Procter & Gamble | Enteric-coated anti-inflammatory compositions |
US4853229A (en) * | 1987-10-26 | 1989-08-01 | Alza Corporation | Method for adminstering tiny pills |
-
1990
- 1990-06-07 NZ NZ233975A patent/NZ233975A/en unknown
- 1990-06-13 FI FI902964A patent/FI902964A0/fi not_active IP Right Cessation
- 1990-06-14 MX MX2116590A patent/MX21165A/es unknown
- 1990-06-14 IL IL94735A patent/IL94735A0/xx unknown
- 1990-06-29 PT PT94552A patent/PT94552A/pt not_active Application Discontinuation
- 1990-07-03 EP EP19900112686 patent/EP0413120A3/en not_active Withdrawn
- 1990-07-05 AU AU58736/90A patent/AU627335B2/en not_active Expired - Fee Related
- 1990-07-12 NO NO90903116A patent/NO903116L/no unknown
- 1990-07-12 KR KR1019900010583A patent/KR910004179A/ko not_active Application Discontinuation
- 1990-07-12 IE IE255490A patent/IE902554A1/en unknown
- 1990-07-13 JP JP2186999A patent/JPH0386827A/ja active Pending
- 1990-08-15 CA CA002023303A patent/CA2023303A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2023303A1 (en) | 1991-02-17 |
JPH0386827A (ja) | 1991-04-11 |
NZ233975A (en) | 1992-06-25 |
NO903116L (no) | 1991-02-18 |
AU5873690A (en) | 1991-02-21 |
IL94735A0 (en) | 1991-04-15 |
MX21165A (es) | 1993-09-01 |
EP0413120A2 (en) | 1991-02-20 |
PT94552A (pt) | 1991-04-18 |
AU627335B2 (en) | 1992-08-20 |
IE902554A1 (en) | 1991-02-27 |
FI902964A0 (fi) | 1990-06-13 |
EP0413120A3 (en) | 1992-02-26 |
NO903116D0 (no) | 1990-07-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |