KR900002652B1 - 모노클로날 항체의 열안정화법 및 이로부터 제조된 조성물 - Google Patents

모노클로날 항체의 열안정화법 및 이로부터 제조된 조성물 Download PDF

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Publication number
KR900002652B1
KR900002652B1 KR1019850005717A KR850005717A KR900002652B1 KR 900002652 B1 KR900002652 B1 KR 900002652B1 KR 1019850005717 A KR1019850005717 A KR 1019850005717A KR 850005717 A KR850005717 A KR 850005717A KR 900002652 B1 KR900002652 B1 KR 900002652B1
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KR
South Korea
Prior art keywords
ovalbumin
composition
monoclonal antibody
hydrolyzed
theophylline
Prior art date
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Expired
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KR1019850005717A
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English (en)
Korean (ko)
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KR860001594A (ko
Inventor
에이취.도지 로버트
제이.아버스 란달
Original Assignee
애보트 래버러토리스
죠셉 엠.버니크
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Application filed by 애보트 래버러토리스, 죠셉 엠.버니크 filed Critical 애보트 래버러토리스
Publication of KR860001594A publication Critical patent/KR860001594A/ko
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Publication of KR900002652B1 publication Critical patent/KR900002652B1/ko
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/826—Additives, e.g. buffers, diluents, preservatives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1019850005717A 1984-08-09 1985-08-08 모노클로날 항체의 열안정화법 및 이로부터 제조된 조성물 Expired KR900002652B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US639,156 1984-08-09
US06/639,156 US4650772A (en) 1984-08-09 1984-08-09 Monoclonal antibody stabilization
US639.156 1984-08-09

Publications (2)

Publication Number Publication Date
KR860001594A KR860001594A (ko) 1986-03-20
KR900002652B1 true KR900002652B1 (ko) 1990-04-21

Family

ID=24562959

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850005717A Expired KR900002652B1 (ko) 1984-08-09 1985-08-08 모노클로날 항체의 열안정화법 및 이로부터 제조된 조성물

Country Status (15)

Country Link
US (1) US4650772A (https=)
EP (1) EP0170983B1 (https=)
JP (1) JPH0699325B2 (https=)
KR (1) KR900002652B1 (https=)
AT (1) ATE57021T1 (https=)
AU (1) AU592952B2 (https=)
CA (1) CA1238284A (https=)
DE (1) DE3579868D1 (https=)
DK (1) DK333185A (https=)
ES (1) ES8702790A1 (https=)
GR (1) GR851926B (https=)
IE (1) IE58626B1 (https=)
IL (1) IL75762A (https=)
NZ (1) NZ212694A (https=)
ZA (1) ZA855248B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ217844A (en) * 1985-10-11 1989-10-27 Sumitomo Pharma A sustained release pharmaceutical composition containing silicone elastomer and an albumin
DE3877015T2 (de) * 1987-02-20 1993-05-06 Akzo Nv Antikoerper enthaltende stabilisierte waesserige zusammensetzung.
US5237054A (en) * 1987-02-20 1993-08-17 Akzo Pharma Stabilized aqueous composition containing antibodies
DE3825429C2 (de) * 1988-07-27 1994-02-10 Biotest Pharma Gmbh Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt
JP2627681B2 (ja) * 1990-07-18 1997-07-09 同仁医薬化工株式会社 マイコプラズマ・ニューモニエ診断用試薬
WO1992001808A1 (fr) * 1990-07-18 1992-02-06 Dojin Iyaku-Kako Co., Ltd. Reactif permettant de diagnostiquer mycoplasma pneumoniae
JPH0565233A (ja) * 1991-03-08 1993-03-19 Mitsui Toatsu Chem Inc モノクローナル抗体含有凍結乾燥製剤
JP2553445B2 (ja) * 1992-12-17 1996-11-13 同仁医薬化工株式会社 抗体の安定化方法
EP0852951A1 (de) 1996-11-19 1998-07-15 Roche Diagnostics GmbH Stabile lyophilisierte pharmazeutische Zubereitungen von mono- oder polyklonalen Antikörpern
AU2006247039B2 (en) * 2005-05-19 2011-03-03 Amgen Inc. Compositions and methods for increasing the stability of antibodies
WO2011093745A1 (en) * 2010-01-26 2011-08-04 Obschestvo S Ogranichennoi Otvetstvennostyu "Nauchno- Proizvodstvennaya Firma "Materia Medika Kholding" Method of determination of autoantibody level by means of enzyme immunoassay

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5816471B2 (ja) * 1977-11-29 1983-03-31 持田製薬株式会社 免疫化学的測定試薬の安定化剤
US4444880A (en) * 1982-07-27 1984-04-24 Syva Company Periodate removal of ascorbate interference in dipsticks for immunoassays
US4439421A (en) * 1982-08-30 1984-03-27 Baxter Travenol Laboratories, Inc. Stabilized gamma globulin concentrate
US4482483A (en) * 1983-04-06 1984-11-13 Armour Pharmceutical Company Composition of intravenous immune globulin

Also Published As

Publication number Publication date
ATE57021T1 (de) 1990-10-15
EP0170983A3 (en) 1988-01-27
KR860001594A (ko) 1986-03-20
CA1238284A (en) 1988-06-21
ES545975A0 (es) 1987-01-16
JPS6176423A (ja) 1986-04-18
US4650772A (en) 1987-03-17
IL75762A (en) 1989-10-31
GR851926B (https=) 1985-12-09
ZA855248B (en) 1986-02-26
IE58626B1 (en) 1993-10-20
DE3579868D1 (de) 1990-10-31
ES8702790A1 (es) 1987-01-16
EP0170983A2 (en) 1986-02-12
NZ212694A (en) 1988-05-30
EP0170983B1 (en) 1990-09-26
AU592952B2 (en) 1990-02-01
DK333185D0 (da) 1985-07-22
JPH0699325B2 (ja) 1994-12-07
IL75762A0 (en) 1985-11-29
DK333185A (da) 1986-02-10
AU4536985A (en) 1986-02-13
IE851964L (en) 1986-02-09

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KR900002652B1 (ko) 모노클로날 항체의 열안정화법 및 이로부터 제조된 조성물
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