KR890017228A - Arrhythmia Treatment - Google Patents

Arrhythmia Treatment Download PDF

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Publication number
KR890017228A
KR890017228A KR1019880006375A KR880006375A KR890017228A KR 890017228 A KR890017228 A KR 890017228A KR 1019880006375 A KR1019880006375 A KR 1019880006375A KR 880006375 A KR880006375 A KR 880006375A KR 890017228 A KR890017228 A KR 890017228A
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South Korea
Prior art keywords
compound
formula
salt
pharmaceutically acceptable
alkyl
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KR1019880006375A
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Korean (ko)
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KR910004674B1 (en
Inventor
에드워드 크로스 피터
에드먼드 에로우스미스 존
Original Assignee
알렌 제이.스피겔
화이자 인코포레이티드
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Priority to KR1019880006375A priority Critical patent/KR910004674B1/en
Publication of KR890017228A publication Critical patent/KR890017228A/en
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Publication of KR910004674B1 publication Critical patent/KR910004674B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/36—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음No content

Description

부정맥치료제Arrhythmia Treatment

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (11)

일반식 (A)의 화합물 또는 이의 염 :Compound of formula (A) or salt thereof: 상기식에서, 각각의 R은 동일하며, -NHSO2(C1-C4알킬), -NH2또는 -NO2이고 ; X는 산소 또는 직접 결합이며 ; Rl은 H, C1-C4알킬, C1-C4알콕시 또는 할로이고 ; n은 1 또는 2인데, 단, X가 산소일 경우, n은 2이 다.Wherein each R is the same and is -NHSO 2 (C 1 -C 4 alkyl), -NH 2 or -NO 2 ; X is oxygen or a direct bond; R 1 is H, C 1 -C 4 alkyl, C 1 -C 4 alkoxy or halo; n is 1 or 2, provided that when X is oxygen, n is 2. 일반식(Ⅰ)의 화합물 또는 이의 약제학적으로 허용되는 염.A compound of formula (I) or a pharmaceutically acceptable salt thereof. 상기식에서, R1은 수소, C1-C4알킬, Cl-C4알콕시 또는 할로이고 ; 각각의 R2는 동일하고, Cl-C4알킬이며 ; X는 산소 또는 직접 결합이고 ; n은 1 또는 2인데, 단, X가 산소일 경우, n은 2이다.Wherein R 1 is hydrogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy or halo; Each R 2 is the same and is C 1 -C 4 alkyl; X is oxygen or a direct bond; n is 1 or 2, provided that when X is oxygen, n is 2. 제 1 항에 있어서, R1이 수소이고, 각각의 R2가 메틸인 화합물.The compound of claim 1, wherein R 1 is hydrogen and each R 2 is methyl. 제 2 항에 있어서, 구조식 (IA)의 화합물.The compound of formula (IA) according to claim 2. 제 2 항 내지 제 4 항중 어느 하나에 따른 일반식(Ⅰ)의 화합물 또는 이의 약제학적으로 허용되는 염, 및 약제학적으로 허용되는 희석제 또는 담체를 함유하는 약제학적 조성물.A pharmaceutical composition comprising a compound of formula (I) according to any one of claims 2 to 4 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable diluent or carrier. 제 2 항 내지 제 4 항중 어느 하나에 있어서, 약제로서 사용하기 위한 일반식(Ⅰ)과 화합물 또는 이의 약제학적으로 허용되는 염.The compound of formula (I) and a compound or a pharmaceutically acceptable salt thereof according to any one of claims 2 to 4 for use as a medicament. 부적맥치료용 약제를 제조하기 위한 제 2 항 내지 제 4 항중 어느 하나에 따른 일반식(Ⅰ)의 화합물 또는 이의 약제학적으로 허용되는 염의 용도.Use of a compound of formula (I) according to any one of claims 2 to 4 or a pharmaceutically acceptable salt thereof for the preparation of a medicament for treating tachycardia. 제 1항에 있어서, 제 4항에 따른 화합물외의, 상기 특정 화합물중은 하나인 일반식(A)의 화합물 또는 이의 염.A compound of formula (A) according to claim 1 or a salt thereof, in addition to the compound according to claim 4, wherein said specific compound is one. 실제로 상기 예시되고, 제 1 항에 정의된 일반식(A)의 화합물 또는 이의 염을 제조하는 방법.A process for preparing a compound of formula (A) or a salt thereof, which is actually exemplified above and defined in claim 1. 제 1 항에 있어서, 제 9 항의 방법에 의해 제조된, 일반식(A)의 화합물 또는 이의 염.The compound of formula (A) or a salt thereof according to claim 1, prepared by the method of claim 9. 제 5 항에 있어서, 실제로 상기된 약제학적 조성물.The pharmaceutical composition according to claim 5, wherein said pharmaceutical composition is actually described above. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019880006375A 1988-05-30 1988-05-30 Antiarrhythmic agents KR910004674B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019880006375A KR910004674B1 (en) 1988-05-30 1988-05-30 Antiarrhythmic agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019880006375A KR910004674B1 (en) 1988-05-30 1988-05-30 Antiarrhythmic agents

Publications (2)

Publication Number Publication Date
KR890017228A true KR890017228A (en) 1989-12-15
KR910004674B1 KR910004674B1 (en) 1991-07-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880006375A KR910004674B1 (en) 1988-05-30 1988-05-30 Antiarrhythmic agents

Country Status (1)

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KR (1) KR910004674B1 (en)

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Publication number Publication date
KR910004674B1 (en) 1991-07-09

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