KR890012940A - 1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논, 이의 제조방법 및 치료적 용도 - Google Patents

1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논, 이의 제조방법 및 치료적 용도 Download PDF

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Publication number
KR890012940A
KR890012940A KR1019890001437A KR890001437A KR890012940A KR 890012940 A KR890012940 A KR 890012940A KR 1019890001437 A KR1019890001437 A KR 1019890001437A KR 890001437 A KR890001437 A KR 890001437A KR 890012940 A KR890012940 A KR 890012940A
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South Korea
Prior art keywords
aminophenyl
hexamethyleneiminopropanone
addition salts
acceptable addition
pharmaceutically acceptable
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KR1019890001437A
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English (en)
Inventor
라퐁 루이
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라보라뜨와르 엘.라퐁
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Publication of KR890012940A publication Critical patent/KR890012940A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음.

Description

1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논, 이의 제조방법 및 치료적 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논 및 약제학적으로 허용되는 이의 부가염중에서 선택된 화합물.
1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논 디하이드로클로라이드.
제1항 또는 2항에 따른 화합물의 유효량 및 치료학적으로 허용되는 부형제를 함유함을 특징으로 하는 치료적 조성물.
우울증 및 우울상태와 관련된 인간의 치료에 사용되는, CNS에 대한 항우울 작용을 갖는 의약적 생성물을 제조하기 위한, 1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논 및 약제학적으로 허용되는 이의 부가염 중에서 선택된 물질의 용도.
면역자극이 필요한 인간의 치료에 사용되는, 면역 자극성 의약적 생성물을 제조하기 위한, 1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논 및 약제학적으로 허용되는 이의 부가염 중에서 선택된 물질의 용도.
산 매질중에서 상응하는 4-아세틸아미노페닐 유도체를 가수분해시킴을 특징으로 하여, 1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논 및 이의 부가염을 제조하는 방법.
1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논 및 약제학적으로 허용되는 이의 부가염중에서 선택된 화합물을 우울증 및 우울상태의 치료를 필요로 하는 인간에게 투여함을 특징으로 하여, 우울증 및 우울상태를 치료하는 방법.
1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논 및 약제학적으로 허용되는 이의 부가염중에서 선택된 화합물을 면역학적 기능의 자극을 필요로 하는 인간에게 투여함을 특징으로 하여, 면역학적 기능을 자극하는 방법.
※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890001437A 1988-02-10 1989-02-09 1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논, 이의 제조방법 및 치료적 용도 KR890012940A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8801565A FR2626881B1 (fr) 1988-02-10 1988-02-10 1-(4-aminophenyl)-2-hexamethyleneiminopropanone, procede de preparation et utilisation en therapeutique
FR8801565 1988-02-10

Publications (1)

Publication Number Publication Date
KR890012940A true KR890012940A (ko) 1989-09-20

Family

ID=9363135

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890001437A KR890012940A (ko) 1988-02-10 1989-02-09 1-(4-아미노페닐)-2-헥사메틸렌이미노프로파논, 이의 제조방법 및 치료적 용도

Country Status (10)

Country Link
US (1) US4983599A (ko)
EP (1) EP0328460A3 (ko)
JP (1) JPH01316369A (ko)
KR (1) KR890012940A (ko)
CN (1) CN1035290A (ko)
DK (1) DK52989A (ko)
FR (1) FR2626881B1 (ko)
IL (1) IL89186A0 (ko)
NO (1) NO890519L (ko)
PT (1) PT89666A (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994008964A1 (en) * 1992-10-16 1994-04-28 Asahi Kasei Kogyo Kabushiki Kaisha N-phenethylazepine derivative and use thereof
FR2849029B1 (fr) 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2569184A1 (fr) * 1984-08-20 1986-02-21 Lafon Labor Derives de 1-(aminophenyl) therapeutique et leur procede de preparation

Also Published As

Publication number Publication date
FR2626881B1 (fr) 1990-07-27
FR2626881A1 (fr) 1989-08-11
PT89666A (pt) 1989-10-04
EP0328460A2 (fr) 1989-08-16
US4983599A (en) 1991-01-08
NO890519L (no) 1989-08-11
CN1035290A (zh) 1989-09-06
EP0328460A3 (fr) 1990-05-23
IL89186A0 (en) 1989-09-10
DK52989D0 (da) 1989-02-03
NO890519D0 (no) 1989-02-08
JPH01316369A (ja) 1989-12-21
DK52989A (da) 1989-08-11

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