KR890005068A - 에탄온 옥심 - Google Patents

에탄온 옥심 Download PDF

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Publication number
KR890005068A
KR890005068A KR1019880011433A KR880011433A KR890005068A KR 890005068 A KR890005068 A KR 890005068A KR 1019880011433 A KR1019880011433 A KR 1019880011433A KR 880011433 A KR880011433 A KR 880011433A KR 890005068 A KR890005068 A KR 890005068A
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KR
South Korea
Prior art keywords
group
carbon atoms
piperazino
alkyl
alkyl substituted
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KR1019880011433A
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English (en)
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KR960001206B1 (ko
Inventor
신이찌로 후지모리
사또시 야마자끼
마모루 스가노
마꼬또 가와무라
구니히로 니노미야
야끼히로 도베
이세이 니따
Original Assignee
원본미기재
미쓰비시 가세이 가부시끼가이샤
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Publication of KR890005068A publication Critical patent/KR890005068A/ko
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Publication of KR960001206B1 publication Critical patent/KR960001206B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/30—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with acyl radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/76—Dibenzothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

내용 없음

Description

에탄온 옥심
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 하기 일반식(I)의 에탄온 옥심 또는 약학적으로 허용되는 그의 산부가염 :
    상기식에서, R1은 시클로아킬기, 아릴기, 아르알킬기, 아릴옥시기, 아르알킬옥시기, 아릴티오기, 아릴술포닐기(이들기는 1 내지 3의 탄소원자를 갖는 알킬기, 1 내지 3의 탄소원자를 갖는 알콕시기 및 할로겐원자로부터 선택된 치환체에 의해 임으로 치환됨), 피페리니도기, 페네라지노기, 4-알킬치환 피페라지노기, 이미다졸기, 4-알킬치환 이미다졸이기 또는 치환된 아미노기이고, R2는 수소원자 또는 1 내지 3의 탄소원자를 갖는 알콕시기이고, 그리고 R3는 피페리디노기, 피페라지노기 또는 4-알킬 치환된 피페라지노기이고, 또는 R1및 R2는 서로 결합된 페닐기와 함께 페노티아진-2-일기, N-아세틸-페노티아진-2-일기, 티안트렌-2-일기, 디벤조티오펜-3-일기, 디벤조푸란-3-일기 또는 하기 일반식의 기
    이고, 상기식에서, R4는 수소원자 또는 1 내지 3의 탄소원자를 갖는 알킬기이다.
  2. 주성분으로 하기 일반식(I)의 에탄온 옥심 또는 약학적으로 허용되는 그의 산부가염을 포함하는 항궤양 작용을 갖는 의약 조성물 :
    상기식에서, R1은 시클로아킬기, 아릴기, 아르알킬기, 아릴옥시기, 아르알킬옥시기, 아릴티오기, 아릴술포닐기(이들 기는 1 내지 3의 탄소원자를 갖는 알킬기, 1 내지 3의 탄소원자를 갖는 알콕시기 및 할로겐원자로부터 선택된 치환체에 의해 임으로 치환됨), 피페리니도기, 피페라지노기, 4-알킬치환 피페라지노기, 아미다졸기, 4-알킬치환 이미다졸이기 또는 치환된 아미노기이고, R2는 수소원자 또는 1 내지 3의 탄소원자를 갖는 알콕시기이고, 그리고 R3는 피페리디노기, 피페라지노기 또는 4-알킬 치환된 피페라지노기이고, 또는 R1및 R2는 서로 결합된 페닐기와 함께 페노티아진-2-일기, N-아세틸-페노티아진-2-일기, 티안트렌-2-일기, 디벤조티오펜-3-일기, 디벤조푸란-3-일기 또는 하기 일반식의 기
    이고, 상기식에서, R4는 수소원자 또는 1 내지 3의 탄소원자를 갖는 알킬기이다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880011433A 1987-09-03 1988-09-03 에탄온 옥심 KR960001206B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP62220877A JPS6463574A (en) 1987-09-03 1987-09-03 Ethanone oximes
JP62-220877 1987-09-03
JP220877/87 1987-09-03

Publications (2)

Publication Number Publication Date
KR890005068A true KR890005068A (ko) 1989-05-11
KR960001206B1 KR960001206B1 (ko) 1996-01-24

Family

ID=16757937

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880011433A KR960001206B1 (ko) 1987-09-03 1988-09-03 에탄온 옥심

Country Status (8)

Country Link
US (2) US4933344A (ko)
EP (1) EP0306411B1 (ko)
JP (1) JPS6463574A (ko)
KR (1) KR960001206B1 (ko)
AT (1) ATE83233T1 (ko)
CA (1) CA1338711C (ko)
DE (1) DE3876546T2 (ko)
HU (1) HU201036B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994018172A1 (en) * 1993-02-01 1994-08-18 Yoshitomi Pharmaceutical Industries, Ltd. Imidazolylbenzene compound and use thereof as medicine
US5665756A (en) * 1994-08-03 1997-09-09 Hoechst Marion Roussel, Inc. Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders
JP2007197390A (ja) * 2006-01-27 2007-08-09 Fujifilm Corp オキシム誘導体、感光性組成物、パターン形成材料、感光性積層体、並びにパターン形成装置及びパターン形成方法
KR102423976B1 (ko) * 2014-08-01 2022-07-22 가부시키가이샤 아데카 신규 중합 개시제 및 상기 중합 개시제를 함유하는 라디칼 중합성 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639612A (en) * 1969-05-16 1972-02-01 Lilly Co Eli Chalcogen containing heterocyclics as an in vitro anti-viral agent
JPS5321023B2 (ko) * 1971-10-06 1978-06-30
FR2162312B1 (ko) * 1971-12-10 1975-02-07 Buzas Andre
US4352804A (en) * 1978-07-25 1982-10-05 Acf Chemiefarma Nv Oxime ethers, their preparation and pharmaceutical compositions containing them
DE3508398A1 (de) * 1985-03-08 1986-11-06 Hoechst Ag, 6230 Frankfurt Fungizide mittel auf der basis von 3-(hetero)-arylpropylaminen sowie neue (hetero)-aryl-propylamine und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ATE83233T1 (de) 1992-12-15
EP0306411A2 (en) 1989-03-08
US4977151A (en) 1990-12-11
DE3876546T2 (de) 1993-04-15
EP0306411B1 (en) 1992-12-09
CA1338711C (en) 1996-11-12
JPS6463574A (en) 1989-03-09
EP0306411A3 (en) 1990-05-30
HU201036B (en) 1990-09-28
HUT47535A (en) 1989-03-28
DE3876546D1 (de) 1993-01-21
KR960001206B1 (ko) 1996-01-24
JPH0465067B2 (ko) 1992-10-16
US4933344A (en) 1990-06-12

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