KR880002856A - Method for preparing diamino pyrimidine derivative - Google Patents

Method for preparing diamino pyrimidine derivative Download PDF

Info

Publication number
KR880002856A
KR880002856A KR1019860007046A KR860007046A KR880002856A KR 880002856 A KR880002856 A KR 880002856A KR 1019860007046 A KR1019860007046 A KR 1019860007046A KR 860007046 A KR860007046 A KR 860007046A KR 880002856 A KR880002856 A KR 880002856A
Authority
KR
South Korea
Prior art keywords
formula
compound
preparing
group
pyrimidine derivative
Prior art date
Application number
KR1019860007046A
Other languages
Korean (ko)
Other versions
KR890001403B1 (en
Inventor
정상헌
최재홍
Original Assignee
허신구
주식회사 럭키
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 허신구, 주식회사 럭키 filed Critical 허신구
Priority to KR1019860007046A priority Critical patent/KR890001403B1/en
Publication of KR880002856A publication Critical patent/KR880002856A/en
Application granted granted Critical
Publication of KR890001403B1 publication Critical patent/KR890001403B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음No content

Description

디아미노 피리미딘 유도체의 제조방법Method for preparing diamino pyrimidine derivative

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (4)

일반식(Ⅱ)의 화합물을 유기용매중에서 일반식(Ⅶ)의 화합물과 반응시켜 일반식(Ⅷ)의 반응성 포스페이트 유도체를 제조하고, 이를 산화시켜 일반식(Ⅸ)의 화합물을 제조한 다음 피페리딘과 치환 반응시킴을 특징으로 하는 일반식(Ⅰ)의 화합물 제조방법.A compound of formula (II) is reacted with a compound of formula (IV) in an organic solvent to prepare a reactive phosphate derivative of formula (IV), followed by oxidation to prepare a compound of formula (IV), and then piperi A process for preparing a compound of formula (I), characterized in that the substitution reaction with dean. 상기식에서 R2는 C1-4의 알콕시기, 치환 가능한 이릴기 또는 아릴옥시기를 나타내며, X염소, 브롬 및 아지도기를 나타낸다.In the formula, R 2 represents a C 1-4 alkoxy group, a substituted aryl group or an aryloxy group, and represents X chlorine, bromine and azido groups. 제1항에 있어서, 유기용매가 N,N-디메틸포롬아미드, N,N-디메틸아세트아미드, 디클로로메탄, 아세톤, 테트라하이드로푸란임을 특징으로 하는 일반식(Ⅰ)의 화합물 제조방법.The method for preparing a compound of formula (I) according to claim 1, wherein the organic solvent is N, N-dimethylformromamide, N, N-dimethylacetamide, dichloromethane, acetone, tetrahydrofuran. 제1항에 있어서, 일반식(Ⅶ)의 화합물을 일반식(Ⅱ)의 화합물을 기준으로 1.0-1.5당량 사용함을 특징으로 하는 일반식(Ⅰ)의 화합물 제조방법.The method for preparing a compound of formula (I) according to claim 1, wherein the compound of formula (VII) is used in an amount of 1.0 to 1.5 equivalents based on the compound of formula (II). 제1항에 있어서, 산화제는 다음 일반식(Ⅹ)의 화합물임을 특징으로 하는 일반식(Ⅰ)의 화합물 제조방법.The method for preparing a compound of formula (I) according to claim 1, wherein the oxidizing agent is a compound of the following general formula (VII). 상기식에서, R3, R4, R5는 동일하거나 상이한 것으로 수소, 염소, 브롬, 알킬기, 알콕시기, 니트로기를 나타낸다.In the above formula, R 3 , R 4 , R 5 are the same or different and represent hydrogen, chlorine, bromine, alkyl group, alkoxy group, nitro group. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019860007046A 1986-08-25 1986-08-25 Process for preparing diamino pyrimidine derivatives KR890001403B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019860007046A KR890001403B1 (en) 1986-08-25 1986-08-25 Process for preparing diamino pyrimidine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019860007046A KR890001403B1 (en) 1986-08-25 1986-08-25 Process for preparing diamino pyrimidine derivatives

Publications (2)

Publication Number Publication Date
KR880002856A true KR880002856A (en) 1988-05-11
KR890001403B1 KR890001403B1 (en) 1989-05-02

Family

ID=19251914

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860007046A KR890001403B1 (en) 1986-08-25 1986-08-25 Process for preparing diamino pyrimidine derivatives

Country Status (1)

Country Link
KR (1) KR890001403B1 (en)

Also Published As

Publication number Publication date
KR890001403B1 (en) 1989-05-02

Similar Documents

Publication Publication Date Title
KR830010104A (en) Method for preparing an arylphenyl ether derivative
KR840006994A (en) Tris (piperidylaminotriazilamino) compound and preparation method of acid addition salt thereof
KR840006482A (en) Method for preparing [3,4-b] pyridine derivative with dihydropyrazolo
KR880701234A (en) Novel biphenyl derivatives and methods for their preparation and uses
KR880002856A (en) Method for preparing diamino pyrimidine derivative
KR850002460A (en) Process for preparing carbamate compound
KR870007881A (en) Process for preparing novel alkylenediamine derivatives
ATE61577T1 (en) FLUORINATED VITAMIN D3 DERIVATIVES AND PROCESS FOR THEIR PRODUCTION.
KR840006234A (en) Manufacturing method of 1,3-dithiane
KR840005723A (en) Manufacturing method of thiazole derivative
KR850007256A (en) Method for preparing tricyclic imidazole derivatives
KR830004322A (en) Anti-allergic and anti-ulcer agents 1-oxo-1H-thiazolo [3,2-a] pyrimidine-2-carboxamide and its intermediates
KR830009111A (en) Method for producing peniclanic acid esters
KR870011103A (en) Manufacturing method of cyclic rain lea
KR830010073A (en) Method for preparing 1,4-dihydropyridine derivative
KR840000479A (en) Method for preparing herbicidal compound derived from phenoxybenzoic acid
KR850004090A (en) Method for preparing 2-chloro-3-trifluoro methylbenzaldehyde
KR860000295A (en) Method for preparing oxycam derivative
KR830010096A (en) Method for preparing xylene derivatives
KR830007639A (en) Process for preparing lactam compound
KR860004024A (en) Indole manufacturing method
KR870010014A (en) Method for producing sulfonylurea
KR870003055A (en) Insecticidal compounds
KR860001832A (en) Method for preparing alpha-L-aspartyl-L-phenylalanine alkyl ester
KR880001672A (en) Method for preparing cefem derivatives

Legal Events

Date Code Title Description
A201 Request for examination
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 19970411

Year of fee payment: 9

LAPS Lapse due to unpaid annual fee